Chemokine News and Research

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Chemokines are a family of small cytokines, or proteins secreted by cells. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape.

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Researchers evaluated the impact of CMV seropositivity on humoral and cellular immune responses generated after double and/or triple mRNA vaccination against SARS-CoV-2 among the elderly.

31 May 2022

Direct comparison of immune memory responses to four COVID-19 vaccines

Researchers evaluated host immune responses to four COVID-19 vaccines representing three different vaccine technology platforms, focusing on immune memory responses.

30 May 2022

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

A recent study posted to the bioRxiv* preprint server illustrated that specific chemokine antibodies aid in recognizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent individuals with a desirable disease course.

26 May 2022

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Patients with non-alcoholic fatty liver disease (NAFLD) are at higher risk of cardiovascular disease, because NAFLD prompts the over-production of a class of proteins that cause inflammation and damage to their blood vessels.

25 May 2022

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

A new study investigated whether a specific population of local Bmem cells in the proximal LNs produce secondary GC responses that are different from those at distal sites and if the location in humoral immunity is relevant only to nonlymphoid tissues.

23 May 2022

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Researchers determine whether mutations in the Omicron NTD influence its potential to stimulate myeloid cells and enhance inflammatory cytokine release.

22 May 2022

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In a recent study posted to the journal Nature, researchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities.

20 May 2022

In-depth characterization of the BA.2 versus BA.1 variant

In a recent study published in the journal Nature, researchers evaluated the pathogenicity and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 variant in hamsters and mice.

19 May 2022

RGS2 protein expression may explain reduced sense of smell in COVID

Researchers tested the hypothesis that anosmia in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected individuals elevates the expression of the odorant receptor, a regulator of G protein signaling 2 (RGS2) in humans.

18 May 2022

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

In a new study, researchers evaluated the BNT162b2 coronavirus disease 2019 mRNA vaccine (antigen)-specific immune response among myeloid dysplastic syndrome and chronic lymphocytic leukemia patients.

18 May 2022

An atlas of human immune cells across tissues

In a recent article published in the Science journal, researchers demonstrated tissue-specific immune cell characteristics in humans by performing cross-tissue immune cell evaluation.

16 May 2022

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Researchers compared the immunogenicity of or and reactogenicity to the BNT162b2 vaccine in Japanese adults and elders.

16 May 2022

Study reveals serum proteomic signatures of long COVID patients

In a recent study posted to the bioRxiv*preprint server, researchers evaluated the serum proteomic signatures of long coronavirus disease (COVID) patients.

13 May 2022

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A new study explored key vaccine features which could help induce and preserve humoral immunity against SARS-CoV-2 infection.

11 May 2022

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

In this study, the authors have specifically studied the interactions of epithelial cells, a subset of cytokines and macrophages.

10 May 2022

Chemokine News and Research

Further Reading

The effect of CMV serostatus on humoral and cellular measures of vaccine responses after 2 and 3 doses of SARS-CoV-2 mRNA vaccines in older adults

Direct comparison of immune memory responses to four COVID-19 vaccines

After SARS-CoV-2 infection, anti-chemokine antibodies correlate with better outcomes

NTU scientists discover why NAFLD patients are at higher risk of cardiovascular disease

Study suggests that recall of B cell memory may depend on relative locations of prime and boost immunization

Olverembatinib a potent inhibitor of Omicron NTD-mediated cytokine release

Natural immunity weak and short-lived in unvaccinated after Omicron infection

In-depth characterization of the BA.2 versus BA.1 variant

RGS2 protein expression may explain reduced sense of smell in COVID

Triple BNT162b2 vaccination found to establish long-term T lymphocyte immunity among MDS and CLL patients

An atlas of human immune cells across tissues

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Study reveals serum proteomic signatures of long COVID patients

Vaccine features that could induce durable humoral immune responses against SARS-CoV-2

A hybrid, multiscale, individual-based model to study the within-host spread of SARS-CoV-2 and the subsequent innate immune response

Scientists explore immunopathology of COVID-19

miRNAs associated with varying clinical presentations of SARS-CoV-2

Safety and immunogenicity of three-dose vaccination with the Pfizer/BioNtech SARS-CoV-2 mRNA vaccine

Artificial circular RNAs found to bypass cellular antiviral responses

Review aims to deepen the understanding of the role of natural killer cells in COVID-19

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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