Chloroquine News and Research

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Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

A recent study demonstrated that the phytochemical curcumin is a potent therapeutic prospect against the SARS-CoV-2 Omicron variant

29 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

Scientists discuss the pathogenic characteristics of SARS-CoV-2 and available therapeutic interventions for treating COVID-19.

3 Apr 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Researchers evaluated the survival benefit conferred by PLEX in patients with severe COVID-19 and cytokine-storm syndrome.

14 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Most DMARDs not linked with the risk of Parkinson's disease in people with rheumatoid arthritis

The autoimmune disorder rheumatoid arthritis has been associated with a lower risk of Parkinson's disease (PD) in previous studies, with antirheumatic drugs as one possible explanatio

24 Jan 2022

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the efficacy of hydroxychloroquine and chloroquine in the treatment of patients hospitalized with COVID-19.

17 Jan 2022

Small molecule identified as a SARS-CoV-2 inhibitor

A new study published in iScience reports the results of a screening strategy to identify small molecules that target viral entry to block infection with this virus.

6 Jan 2022

Traditional medicinal plant alleviates malaria symptoms in mice

The active plant ingredient anemonin could provide a new approach in the treatment of malaria. It was identified by researchers from Ethiopia and Germany in a buttercup that is traditionally used in some African countries as a medicinal plant to treat malaria.

20 Dec 2021

Hospitals refused to give patients ivermectin. Lockdowns and political pressure followed.

One Montana hospital went into lockdown and called police after a woman threatened violence because her relative was denied her request to be treated with ivermectin.

2 Dec 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Scientists develop new approach to combat treatment-resistant melanoma

Researchers from the Centenary Institute have developed a new approach to fighting melanomas that fail to respond – or are resistant – to standard treatments. The deadliest form of skin cancer, melanoma is responsible for more than 1,700 deaths each year in Australia.

30 Oct 2021

Chloroquine News and Research

Study finds curcumin is a potential therapeutic agent against the Omicron variant of SARS-CoV-2

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

An in-depth analysis of pathogenesis of SARS-CoV-2 and therapeutic options for COVID-19

The importance of the endosomal pathway for SARS-CoV-2 entry

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

How have human organoids been used in research to study SARS-CoV-2?

Most DMARDs not linked with the risk of Parkinson's disease in people with rheumatoid arthritis

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Small molecule identified as a SARS-CoV-2 inhibitor

Traditional medicinal plant alleviates malaria symptoms in mice

Hospitals refused to give patients ivermectin. Lockdowns and political pressure followed.

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Scientists develop new approach to combat treatment-resistant melanoma

Malaria: An Interview with the World Health Organization

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A survey on computational methods in discovering protein inhibitors of SARS-CoV-2

Potential covalent SARS-CoV-2 spike protein inhibitors

Study highlights the usefulness of organoids for basic research into coronaviruses

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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