Chromosome 4 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 4, one copy inherited from each parent, form one of the pairs. Chromosome 4 spans more than 191 million DNA building blocks (base pairs) and represents more than 6 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 4 likely contains between 1,300 and 1,600 genes.

Genes on chromosome 4 are among the estimated 20,000 to 25,000 total genes in the human genome.
USF study: HHV-6 causes permanent infection by inserting its DNA into human chromosomes

USF study: HHV-6 causes permanent infection by inserting its DNA into human chromosomes

ITCH gene causes multisystem autoimmune disorder

ITCH gene causes multisystem autoimmune disorder

RDS launches international outreach program on cognitive impairment in Down syndrome patients

RDS launches international outreach program on cognitive impairment in Down syndrome patients

Scientists identify  EoE-associated region in human chromosome

Scientists identify EoE-associated region in human chromosome

Pediatrics researchers identify major gene location responsible for EoE

Pediatrics researchers identify major gene location responsible for EoE

ARIAD Pharmaceuticals' investigational pan-BCR-ABL inhibitor receives FDA and EMA orphan drug designation

ARIAD Pharmaceuticals' investigational pan-BCR-ABL inhibitor receives FDA and EMA orphan drug designation

Determining personal risk for genetic disorders essential

Determining personal risk for genetic disorders essential

Researchers find gene regulator that plays key role in DS-AMKL

Researchers find gene regulator that plays key role in DS-AMKL

For people who carry common gene variants, smoking increases risk of aneurysm

For people who carry common gene variants, smoking increases risk of aneurysm

MLL cancer cells rely on normal protein to proliferate

MLL cancer cells rely on normal protein to proliferate

Ferring Pharmaceuticals, GSN sign agreement to test Parental Support technology

Ferring Pharmaceuticals, GSN sign agreement to test Parental Support technology

QR Pharma awarded patent covering use of Posiphen and analogs in treatment of DS

QR Pharma awarded patent covering use of Posiphen and analogs in treatment of DS

ES cells-functions: Condensins promote mitotic progression and maintain interphase chromatin compaction

ES cells-functions: Condensins promote mitotic progression and maintain interphase chromatin compaction

New genetic data may help predict risk for end-stage kidney disease

New genetic data may help predict risk for end-stage kidney disease

DNA interval in unexplored region of human genome increases risk for coronary artery disease

DNA interval in unexplored region of human genome increases risk for coronary artery disease

Researchers use new technology to reveal different genetic patterns of neuroblastoma

Researchers use new technology to reveal different genetic patterns of neuroblastoma

New gene locus influencing risk for atrial fibrillation identified

New gene locus influencing risk for atrial fibrillation identified

Researchers identify common gene variant associated with atrial fibrillation

Researchers identify common gene variant associated with atrial fibrillation

Children born through assisted reproduction at greater risk of obesity and type 2 diabetes related defects

Children born through assisted reproduction at greater risk of obesity and type 2 diabetes related defects

Scientists develop new mathematical model to understand CML better

Scientists develop new mathematical model to understand CML better

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