Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 6, one copy inherited from each parent, form one of the pairs. Chromosome 6 spans about 171 million base pairs (the building blocks of DNA) and represents between 5.5 percent and 6 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 6 likely contains between 1,100 and 1,600 genes.
Genes on chromosome 6 are among the estimated 20,000 to 25,000 total genes in the human genome.
A team of scientists led by Peer Bork, Ph.D., Senior Bioinformatics Scientist at the European Molecular Biology Laboratory, report today in the journal Genome Research that they have identified a new primate-specific gene family that spans about 10% of human chromosome 2.
Alan List, M.D., leader of the Hematologic Malignancies Program at the H. Lee Moffitt Cancer Center & Research Institute, recently conducted a phase I/II trial of the experimental drug Revlimid showing promise as an innovative way to treat patients with myelodysplastic syndrome (MDS), a form of pre-leukemia.
Twice as many boys as girls are referred to medical specialists for evaluation of short stature or poor growth, according to a new study.
A gene that's normally silenced after contributing to brain development was found to be expressed in cells from medulloblastoma, the most common form of pediatric brain malignancy in children, scientists report in an article published in the February 1 issue of the journal Cancer Research.
In the first-ever study combing the entire human genome for genetic determinants of male sexual orientation, a University of Illinois at Chicago researcher has identified several areas that appear to influence whether a man is heterosexual or gay.
In genetic mapping of a large family with several members affected by a type of heart failure called dilated cardiomyopathy (DCM), the Mayo Clinic team found a defect in a gene on chromosome 3 called SCN5A.
National health records have shown that African-Americans are more prone to high blood pressure than Caucasians, but pinning down the roots of that difference has proven elusive. Now, researchers at the Stanford University School of Medicine have narrowed down the search for genes that contribute to this difference in disease risk.
Scientists have reported in the journal Genome Research that they have successfully cloned and characterized a previously intractable DNA sequence: a 554-kilobase-pair genomic segment near the centromere of the human Y chromosome. This sequence contains eight putatively active genes that could be implicated in sex-associated height differences and gonadal tumor development.
Malaria is one of the world's major killers. More than 500 million people live in epidemic regions and some 2 million - mostly children - die each year. And each year, drug resistance increases in the malarial parasite, Plasmodium falciparum, and the search for new treatments becomes more desperate.
Corticosteroids can be beneficial in the treatment of Duchenne muscular dystrophy and can be offered as a treatment option, according to the American Academy of Neurology and the Child Neurology Society in a new practice guideline published in the January 11 issue of Neurology, the scientific journal of the American Academy of Neurology.
A new family of genes called Novel Structure Proteins (NSP) discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University’s College of Science and Technology could have the potential for predicting the possibility of tumor growth in a patient.
Two specific areas in chromosome 7 and chromosome 16 have been associated with photosensitivity, an epilepsy-related trait, by a team of European scientists in the January issue of Human Molecular Genetics.
A woman's risk of ovarian cancer rises significantly if she carries either of two previously unexamined variations in the gene that codes for the progesterone receptor, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California.
In a study that could benefit medical and food-safety research, scientists have used comparative genomics tools to find clues about why some strains of the bacterium Campylobacter – which each year cause more than 400 million cases of gastrointestinal disease – are more virulent than others.
By impaling individual chromosomes with glass needles one thousandth the diameter of a human hair, a Duke University graduate student has tested their "stickiness" to one another during cell division. Her uncanny surgical skills have added a piece to the large and intricate puzzle of how one cell divides into two -- a process fundamental to all organisms.
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).
Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.
Sometime between the age of 6 and 18 months, after a period of seemingly normal development, girls affected with Rett Syndrome lose interest in play; they gradually become withdrawn and anxious, develop autistic-like behaviors, and acquire specific symptoms like repetitive teeth-grinding and hand-wringing.
Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.
Two Hershey, Pa., researchers were part of a team that has uncovered what may be an important genetic risk factor for amyotrophic lateral sclerosis (ALS).
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