Chromosome Y News and Research

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The Y chromosome is one of the two sex chromosomes in humans (the other is the X chromosome). The sex chromosomes form one of the 23 pairs of human chromosomes in each cell. The Y chromosome spans about 58 million base pairs (the building blocks of DNA) and represents almost 2 percent of the total DNA in cells.

Each person normally has one pair of sex chromosomes in each cell. The Y chromosome is present in males, who have one X and one Y chromosome, while females have two X chromosomes.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. The Y chromosome likely contains between 70 and 200 genes. Because only males have the Y chromosome, the genes on this chromosome tend to be involved in male sex determination and development. Sex is determined by the SRY gene, which is responsible for the development of a fetus into a male. Other genes on the Y chromosome are important for male fertility.

Many genes are unique to the X or Y chromosome, but genes in an area known as the pseudoautosomal region are present on both chromosomes. As a result, men and women each have two functional copies of these genes. Many genes in the pseudoautosomal region are essential for normal development.

Genes on the Y chromosome are among the estimated 20,000 to 25,000 total genes in the human genome.
Scientists have discovered a genetic cause of cleft lip and palate in mice

Scientists have discovered a genetic cause of cleft lip and palate in mice

Transplanted bone-marrow cells could regenerate nerve cells in the brain

Transplanted bone-marrow cells could regenerate nerve cells in the brain

Lou Gehrig’s disease gene discovered

Lou Gehrig’s disease gene discovered

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

Clinical trial of enzyme replacement therapy for the treatment of Gaucher disease

New techniques to search the yeast genome for genes that help keep copied chromosomes together

New techniques to search the yeast genome for genes that help keep copied chromosomes together

New method that will revolutionize the search for genes

New method that will revolutionize the search for genes

New information on genetic shuffling before egg or sperm formation rewrites genetic theory

New information on genetic shuffling before egg or sperm formation rewrites genetic theory

Extensive gene traffic, the process of genes leaving and arriving on the chromosome

Extensive gene traffic, the process of genes leaving and arriving on the chromosome

Scientists discover gene for Parkinson's disease

Scientists discover gene for Parkinson's disease

Genetic mutation raises interesting questions about the evolution of the Y chromosome

Genetic mutation raises interesting questions about the evolution of the Y chromosome

Autism gene discovered

Autism gene discovered

Surprises found In gene variation associated with schizophrenia

Surprises found In gene variation associated with schizophrenia

Researchers isolate gene responsible for Chron's disease

Researchers isolate gene responsible for Chron's disease

Completion of the sequencing of human chromosome 19

Completion of the sequencing of human chromosome 19

Launch of The Oxford Genetics Knowledge Park by Matt Ridley

Launch of The Oxford Genetics Knowledge Park by Matt Ridley

How rat's genetic blueprint stacks up against those of mice and humans

How rat's genetic blueprint stacks up against those of mice and humans

Gene-rich human Chromosome 19 sequence completed

Gene-rich human Chromosome 19 sequence completed

Discovery of new gene sheds light on human brain development

Discovery of new gene sheds light on human brain development

Scientists identify blood development gene which may aid the fight against cancer and leukemia

Scientists identify blood development gene which may aid the fight against cancer and leukemia

Gene Responsible for The Most Common Form of Diabetes

Gene Responsible for The Most Common Form of Diabetes