Chronic Pain News and Research

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Single mutation in a human sodium channel gene can trigger pain in people with primary erythromelalgia

Yale School of Medicine researchers report the first demonstration that a single mutation in a human sodium channel gene can trigger pain in people with an inherited pain syndrome known as primary erythromelalgia, according to a study published this month in the journal Brain.

13 Jul 2005

Neurological complication may result from rapid withdrawal from pregabalin

A report in the July Annals of Neurology describes a serious adverse event experienced by a participant in a clinical trial that may raise a new caution about the use of antiepileptic drugs for conditions other than epilepsy.

6 Jul 2005

Helping children deal with chronic pain

One in fifty children and adolescents live with severely debilitating and recurrent pain but there is an "embarrassing" lack of data on the best ways to treat them, according to researchers.

6 Jul 2005

Drug abusers are increasingly turning to a slow-release form of drug fentanyl

Drug abusers are increasingly turning to a slow-release form of a powerful painkiller for a quick and dangerous high, University of Florida researchers warn. The trend is raising alarm as the number of people dying from an overdose of the drug fentanyl, an opioid 100 times more potent than morphine, rises.

6 Jul 2005

Canada first country to approve cannabis based painkiller

Canada has become the first country to approve a cannabis based painkiller for multiple sclerosis (MS) patients.

21 Jun 2005

Study sheds light on endometriosis pain

Women with endometriosis often have several types of chronic pain conditions because their abnormal growths develop a nerve supply that communicates with the brain, new research suggests.

10 Jun 2005

Combining morphine with small doses of methadone could increase the effectiveness of morphine for the treatment of chronic pain

Although morphine is well known as a highly effective analgesic, its clinical utility is severely limited by the development of drug tolerance, the requirement for increasing doses to maintain analgesic effect, and the development of physical dependence.

6 Jun 2005

U.S. Supreme Court overules states and makes marijuana for medicinal use illegal

A U.S. Supreme Court has decreed that the Federal Government has the power to prevent sick patients from smoking home-grown marijuana that a doctor recommended to relieve chronic pain. The 6 to 3 ruling by a divided court is a major setback for the medical use of marijuana.

6 Jun 2005

Common over-the-counter cough medication dextromethorphan may help people with fibromyalgia

About 10 million Americans, most of them women suffer from fibromyalgia, an incurable illness that causes stiffness, fatigue, muscle aches and sleep disturbances.

29 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, UCSF medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

23 May 2005

Exercise programme is as beneficial as spinal surgery in treating lower back pain

The largest ever clinical trial of surgery versus exercise treatments for chronic low back pain has found that patients may obtain as much benefit from an intense physical exercise programme as from spinal surgery.

22 May 2005

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Dextromethorphan, an over-the-counter medication that silences coughs, may help fibromyalgia patients quiet over-reacting nerves that amplify ordinary touches into agony.

20 May 2005

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, University of California, San Francisco (UCSF) medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

20 May 2005

Coping with pain quite a struggle for half of the U.S.A.

At least 50 precent of the U.S. population are struggling to cope either with the aggravation of intermittent pain or with the misery of chronic pain which is difficult to treat. This results in less work, crankier moods and fewer activities, combined with a wide-ranging search for pain relief.

11 May 2005

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Does clinical depression bring about chronic pain? Or does pain lead to depression? Because these two conditions frequently co-exist--30 to 54 percent of patients with major depressive disorder also suffer persistent physical pain--there has been much speculation about whether one causes the other or whether a common underlying factor provokes both. Results of studies into the precise nature of this relationship, however, have been inconsistent.

5 May 2005

Schistosomiasis has a greater effect than previosly thought

Schistosomiasis, an infection caused by a parasitic worm, affects more than 200 million worldwide, most of them in Africa and many health workers believe the disabling effects of schistosomiasis have never been adequately quantified.

1 May 2005

Bextra withdrawn from market, strong warnings on popular painkillers

The U.S. Food and Drug Administration (FDA) has issued warnings that most popular painkillers can hurt the heart, stomach and skin, and they have told pharmaceutical giant Pfizer to withdraw Bextra a top selling painkiller.

10 Apr 2005

Three out of every four adults over age 50 use some kind of alternative medicine

This study found that 71 percent of older adults used some form of alternative medicine in 2000. A study done in 2002, found a lower rate -- about 62 percent – among all adults.

10 Apr 2005

Pfizer withdraws Bextra from market

Despite an expert panel stating last month that the three COX-2 drugs Vioxx, Bextra and Celebrex were safe enough to be marketed, the U.S. Food and Drug Administration (FDA) has this week told drug manufacturer Pfizer to remove the drug Bextra from the market and a statement by Pfizer confirms that the European Union regulators have done the same.

7 Apr 2005

Study shows connection of varicose veins to chronic pelvic pain

Research presented today at the Society of Interventional Radiology's 30th Annual Scientific Meeting found that 16 percent of women with varicose veins in their legs simultaneously had ovarian varicose veins -- a common but often under-diagnosed cause of chronic pelvic pain.

4 Apr 2005

Chronic Pain News and Research

Single mutation in a human sodium channel gene can trigger pain in people with primary erythromelalgia

Neurological complication may result from rapid withdrawal from pregabalin

Helping children deal with chronic pain

Drug abusers are increasingly turning to a slow-release form of drug fentanyl

Canada first country to approve cannabis based painkiller

Study sheds light on endometriosis pain

Combining morphine with small doses of methadone could increase the effectiveness of morphine for the treatment of chronic pain

U.S. Supreme Court overules states and makes marijuana for medicinal use illegal

Common over-the-counter cough medication dextromethorphan may help people with fibromyalgia

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Exercise programme is as beneficial as spinal surgery in treating lower back pain

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Coping with pain quite a struggle for half of the U.S.A.

Does clinical depression bring about chronic pain? Or does pain lead to depression?

Schistosomiasis has a greater effect than previosly thought

Bextra withdrawn from market, strong warnings on popular painkillers

Three out of every four adults over age 50 use some kind of alternative medicine

Pfizer withdraws Bextra from market

Study shows connection of varicose veins to chronic pelvic pain

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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