Clinical Trial News and Research

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Innovative cancer treatment approach yields promising results in pediatric patients

Researchers have developed a functional precision medicine approach that targets cancer by combining genetic testing with a new way to test individual drugs on tumor samples.

12 Apr 2024

Low dose esketamine injection after childbirth reduces postpartum depression

A single low dose injection of esketamine given immediately after childbirth reduces major depressive episodes in individuals with depressive symptoms during pregnancy (prenatal depression), finds a clinical trial published by The BMJ today.

12 Apr 2024

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

A noninvasive brain stimulation treatment improved depression and anxiety symptoms among older adults in a new University of Florida-led study.

12 Apr 2024

New natural supplement shows promise in preventing postpartum blues

A new study published in the Lancet discovery science journal eClinicalMedicine has confirmed that a novel natural supplement-;invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH)-;prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth.

10 Apr 2024

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Three early-phase clinical studies presented by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2024 show promising initial data for patients with lymphoma, gastric or gastroesophageal junction cancers, and specific molecularly selected tumors.

10 Apr 2024

Deciphering cancer plasticity:Insights from MSK research

About 90% of deaths from cancer are a result of metastasis -; that is, from cancer's ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain.

10 Apr 2024

Home-administered nasal spray could be safely used to treat recurrent rapid heart rhythms

A clinical trial led by Weill Cornell Medicine investigators showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms.

9 Apr 2024

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Adding a personalized anti-tumor vaccine to standard immunotherapy is safe and about twice as likely to shrink cancer as standard immunotherapy alone for patients with hepatocellular carcinoma, the most common type of liver cancer, according to a clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and its Convergence Institute.

8 Apr 2024

Immersive VR may be a useful non-medication strategy to improve cancer pain

A 10-minute virtual reality (VR) session significantly lessened pain in hospitalized patients with cancer in a recent clinical trial published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Even a day later, participants experienced sustained benefits.

8 Apr 2024

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

A new technology using ultralow temperature cryoablation (ULTC) has eliminated clinical ventricular tachycardia (VT) in 94% of patients. The late-breaking science is presented at EHRA 2024, a scientific congress of the European Society of Cardiology (ESC).

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

When the FDA recently convened a committee of advisers to assess a cardiac device made by Abbott, the agency didn't disclose that most of them had received payments from the company or conducted research it had funded — information readily available in a federal database.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Behavioral economics strategies boost daily walking by 10% in high-risk cardiovascular patients

Strategies such as earning points or small amounts of money encouraged people at high risk for heart disease or stroke to increase their daily walking by about 10% and sustain the increase for a year, according to research being presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Hot climates worsen chronic kidney disease outcomes

Chronic kidney disease patients living in the hottest countries experienced an additional 8% drop in kidney function each year compared to those living in temperate climates, finds a new study from researchers at UCL and the London School of Hygiene & Tropical Medicine (LSHTM).

5 Apr 2024

Structured 'seizure action plan' can help patients with epilepsy to safely manage emergencies

A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status.

5 Apr 2024

PeriCord bioimplants show promise in heart regeneration studies

The promising results obtained in a clinical trial with a pioneering advanced therapy drug named PeriCord, which aims to repair the heart of patients who have suffered a heart attack, confirm the feasibility of new therapies based on the application of stem cells and tissue engineering to promote the regeneration of damaged tissues.

5 Apr 2024

Mayo Clinic research shows health benefits of active workstations

A recent Mayo Clinic study suggests that active workstations incorporating a walking pad, bike, stepper and/or standing desk are successful strategies for reducing sedentary time and improving mental cognition at work without reducing job performance.

4 Apr 2024

BMI influences efficacy of nerve-stimulation treatment for sleep apnea, study finds

A nerve-stimulation treatment for obstructive sleep apnea that originally was approved only for people with body mass indexes (BMIs) in the healthy range recently was extended to patients with BMIs up to 40, a weight range generally described as severely obese.

4 Apr 2024

UCL and Oxford lead major dementia diagnosis trials

Thousands of people in the UK are to take part in countrywide trials to identify accurate and quick blood tests that can diagnose dementia, led by research teams at UCL and Dementias Platform UK, based at the University of Oxford.

4 Apr 2024

Clinical Trial News and Research

Innovative cancer treatment approach yields promising results in pediatric patients

Low dose esketamine injection after childbirth reduces postpartum depression

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

New natural supplement shows promise in preventing postpartum blues

Three early-phase clinical studies show promising initial data for patients with lymphoma, gastric cancers

Deciphering cancer plasticity:Insights from MSK research

Home-administered nasal spray could be safely used to treat recurrent rapid heart rhythms

Personalized anti-tumor vaccine enhances immunotherapy for liver cancer

Immersive VR may be a useful non-medication strategy to improve cancer pain

New cryoablation technique eliminates ventricular tachycardia in 94% of patients

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Behavioral economics strategies boost daily walking by 10% in high-risk cardiovascular patients

Hot climates worsen chronic kidney disease outcomes

Structured 'seizure action plan' can help patients with epilepsy to safely manage emergencies

PeriCord bioimplants show promise in heart regeneration studies

Mayo Clinic research shows health benefits of active workstations

BMI influences efficacy of nerve-stimulation treatment for sleep apnea, study finds

UCL and Oxford lead major dementia diagnosis trials

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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