Cytokine News and Research

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Miniaturized device offers new way to gain insight into cell processes and communication

Like humans, cells of the same species each have a distinct "personality." When confronted with an external stimulus like a virus, they each secrete a different quantity of molecules and communicate with each other to a varying degree.

28 May 2018

CU research sheds light on liver disease caused by intravenous nutrition

Research by physician-scientists at the University of Colorado Anschutz Medical Campus offers hope for improved quality of life for people who rely on intravenous nutrition due to intestinal damage.

24 May 2018

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

23 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

New CRISPR/Cas9 system targets regulatory genes of AIDS virus

By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, a Japanese research group has succeeded in blocking the production of HIV-1 by infected cells.

18 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

New vaccine strategy increases number of tumor-specific cancer-killing T cells

New research published in Cancer Immunology Research by Drs. Esteban Celis and Hussein Sultan of the Georgia Cancer Center at Augusta University could serve as the stepping-stone in constructing vaccines with a greater likelihood of finding and attacking tumors in the human body.

2 May 2018

Common therapy options for psoriasis can help reduce coronary plaque, study shows

Late-breaking clinical science shows common therapy options for psoriasis (PSO)-a chronic inflammatory skin disease-can help reduce coronary plaque. The authors found that not only do the treatments reduce the volume of the plaque, but also the plaque becomes less inflammatory over time harboring fewer characteristics prone to rupture and cause a heart attack.

26 Apr 2018

AYOXXA introduces new LUNARIS Mouse 12-Plex Th17 Kit for quantitative analysis of Th17 cell biology

AYOXXA Biosystems GmbH, an international biotechnology company, focused on the development of innovative multiplex protein analysis technologies enabling translational research in basic and clinical research, today announced the expansion of its catalogue of immunoassays for multiplex protein analysis with the introduction of LUNARIS™ Mouse 12-Plex Th17 Kit for the quantitative analysis of soluble mouse T helper 17 (Th17) cell-related markers.

20 Apr 2018

Novel disease model for ALS and MS can be used to develop new immunotherapies

Researchers at Karolinska Institutet in Sweden have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. The model is described in a publication in the scientific journal Nature Immunology.

16 Apr 2018

Patient's mucus may help predict type of chronic sinusitis

By April, nearly one-third of the U.S. is already experiencing high pollen levels while the weather and temperatures continue to fluctuate, aggravating sinus symptoms. A patient's mucus may predict the type of his or her chronic sinusitis, which could help doctors determine whether surgery or medical treatments can produce the best outcomes, according to a recently published Vanderbilt study.

9 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).

30 Mar 2018

Research offers new understanding about cause of Parkinson's disease

Until very recently, Parkinson's had been thought a disease that starts in the brain, destroying motion centers and resulting in tremors and loss of movement.

21 Mar 2018

American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

Researchers unravel how gingival mesenchymal stem cells accelerate wound healing

Ever notice how a cut inside the mouth heals much faster than a cut to the skin? Gum tissue repairs itself roughly twice as fast as skin and with reduced scar formation. One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give rise to a variety of cell types.

15 Mar 2018

New suggests different approach to eczema treatment

Eczema affects about 17 percent of children in developed countries and is often the gateway to food allergy and asthma, initiating an "atopic march" toward broader allergic sensitization.

6 Mar 2018

Duke researchers show how to retrain immune system of peanut-allergy mice

Treating food allergies might be a simple matter of teaching the immune system a new trick, researchers at Duke Health have found.

21 Feb 2018

Bioactive compound limits collateral damage in the kidneys after heart attack

A heart attack triggers an acute inflammatory response at the damaged portion of the heart's left ventricle. If this acute inflammation lingers, it can lead to stretching of the ventricle and heart failure. The inflammation can claim another victim -- the kidneys.