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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

DNA methylation: A key player in gene expression variation and disease manifestation

Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks.

27 Nov 2023

RNA-based therapy shows promise for treating leukemia in animal models

Each year, about 13,000 people in Deutschland are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer.

27 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Novel method can detect contaminants in T-cell cultures within 24 hours

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE) and Massachusetts Institute of Technology (MIT), have developed a novel method capable of identifying contaminants in T-cell cultures within 24 hours.

27 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

New CRISPR approach shows promise for treating glioblastoma

The gene-editing technology CRISPR shows early promise as a therapeutic strategy for the aggressive and difficult-to-treat brain cancer known as primary glioblastoma, according to findings of a new study from Gladstone Institutes.

27 Nov 2023

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.

27 Nov 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Breakthrough decoding of the Y chromosome revolutionizes digestive disease research

A major breakthrough in human genetics has been achieved with the complete decoding of the human Y chromosome, opening up new avenues for research into digestive diseases.

23 Nov 2023

Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Non-invasive genetic test for fetal DNA sequencing developed

A team of investigators from Massachusetts General Hospital (MGH), Brigham and Women's Hospital (BWH), and the Broad Institute of MIT and Harvard have developed a non-invasive genetic test that can screen the blood of pregnant individuals to survey all genes for fetal DNA sequence variants.

22 Nov 2023

New insights into genetic risk factors for early breast cancer in women of Kazakh ethnicity

A new research paper was published in Oncotarget's Volume 14 on October 4, 2023, entitled, "Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity."

22 Nov 2023

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Using oncolytic viruses (OVs) in combination with nanomaterials as a novel approach to cancer treatment.

22 Nov 2023

Yourgene Health becomes a PacBio compatible partner: Enabling PacBio customers to optimize size selection for long-read sequencing libraries

Yourgene Health (part of the Novacyt group of companies) today announced a collaboration to optimize size selection for long-read sequencing workflows.

From Yourgene Health 22 Nov 2023

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz.

21 Nov 2023

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

The study investigates the role of epigenetic changes in GLP1R gene polymorphisms on metabolically healthy obesity (MHO), revealing that apart from genetic variations, DNA methylation significantly influences the occurrence of MHO.

20 Nov 2023

AI tools show promise in personalized cancer treatment, but lag behind human experts

Treating cancer is becoming increasingly complex, but also offers more and more possibilities. After all, the better a tumor's biology and genetic features are understood, the more treatment approaches there are.

20 Nov 2023

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Pioneering epigenome editing company Tune Therapeutics has announced it is working on a new and potentially curative approach to treating chronic HBV infection.

20 Nov 2023

Study finds high levels of enteric pathogens in children from Alabama's rural areas, highlights sanitation issues

The study reveals a significant presence of enteric pathogens in children from Alabama's Black Belt region, linking well water consumption to increased pathogen detection and underscoring the need for improved sanitation infrastructure.

19 Nov 2023

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

A combined $1.35 million from the Dr. Ralph and Marian Falk Medical Research Trust was awarded to two researchers from the Case Western Reserve University School of Medicine to advance their work on finding more effective treatments-;and better options-;for two debilitating diseases.

17 Nov 2023

DNA News and Research

Further Reading

DNA methylation: A key player in gene expression variation and disease manifestation

RNA-based therapy shows promise for treating leukemia in animal models

Genetic mutation in OXR1 gene linked to brain development issues

Novel method can detect contaminants in T-cell cultures within 24 hours

Synthetic biologists develop versatile platform for targeted drug delivery

New CRISPR approach shows promise for treating glioblastoma

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Breakthrough decoding of the Y chromosome revolutionizes digestive disease research

Exploring the impact of soy isoflavones in prostate cancer therapy

Non-invasive genetic test for fetal DNA sequencing developed

New insights into genetic risk factors for early breast cancer in women of Kazakh ethnicity

Combined application of therapeutic viruses and nanomaterials to revolutionize cancer therapy

Yourgene Health becomes a PacBio compatible partner: Enabling PacBio customers to optimize size selection for long-read sequencing libraries

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

New study links DNA methylation in GLP1R gene to obesity without metabolic disorders

AI tools show promise in personalized cancer treatment, but lag behind human experts

Tune Therapeutics unveils potentially curative approach to treating chronic HBV infection

Study finds high levels of enteric pathogens in children from Alabama's rural areas, highlights sanitation issues

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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