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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

RV262 Phase I study launched to evaluate DNA prime/MVA vector boost vaccine regimen for HIV

A Phase I study, called RV262, recently began to evaluate a combination DNA prime/MVA vector boost vaccine regimen that was developed to protect against diverse subtypes of HIV-1 prevalent in North America, Europe, Africa and South America.

29 Sep 2010

GenMark’s eSensor technology selected for Warfarin clinical study

GenMark Diagnostics, Inc., a provider of automated, multiplex molecular diagnostic testing systems, announced today that their eSensor Warfarin Sensitivity Test has been selected for use in a new pivotal Warfarin clinical study the WARFARIN Trial.

28 Sep 2010

Tel Aviv researchers develop innovative software to analyze and manipulate diseased cells

About ten years ago, the discovery of microRNAs ― tiny cellular molecules that regulate our genetic code ― unlocked a world of scientific possibilities, including a deeper understanding of human disease. One new analytical technology is "deep sequencing," which gives scientists the ability to discover invaluable information about human diseases at a genetic level.

28 Sep 2010

Japanese Patent Office issues patent for ZIOPHARM Oncology's darinaparsin

ZIOPHARM Oncology, Inc. today announced that the Japanese Patent Office has issued a patent, Patent No. 4,571,408, with claims covering pharmaceutical compositions, including oral formulations, of various organic arsenic compounds, including darinaparsin (Zinapar or ZIO-101), and the use of these compositions and the organic arsenic compounds for the treatment of cancer, including as part of a combination therapy.

28 Sep 2010

Women & Infants Hospital receives $2.1M NIH grant to continue work under COBRE for Perinatal Biology

Women & Infants Hospital has recently received a $2.1 million grant from the National Institutes of Health to continue work under the Center of Biomedical Research Excellence for Perinatal Biology. Of the 108 COBREs across the country, Women & Infants is the only one specifically focused on developmental research.

28 Sep 2010

Onconova Therapeutics to present Ex-RAD radioprotectant data at RRS Annual Meeting

Onconova Therapeutics, Inc. is presenting new data in five posters and an oral presentation this week summarizing several studies with the company's radioprotectant Ex-RAD- at the 56th Annual Meeting of the Radiation Research Society (RRS), September 25-29 in Maui, Hawaii.

28 Sep 2010

Scientists identify gene associated with common migraines

An international study led by scientists at Universit- de Montr-al and University of Oxford, has identified a gene associated with common migraines. Their findings show that a mutation in the KCNK18 gene inhibits the function of a protein called TRESK. TRESK normally plays a key role in nerve cell communication. Published today in Nature Medicine, this study may have implications for people who suffer from recurrent headaches, which include more than six million Canadians.

28 Sep 2010

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

Genetic ancestry has no discernible influence on how African American patients with asthma respond to medication, according to a Henry Ford Hospital study.

28 Sep 2010

OpGen completes Series B equity financing

OpGen, Inc., a commercial phase genomics company, today announced the successful completion of a $17 million Series B equity financing.

28 Sep 2010

Michael J. Fox Foundation launches PPMI clinical study to identify Parkinson's disease biomarkers

The Michael J. Fox Foundation has launched the Parkinson's Progression Markers Initiative (PPMI), the first ever large scale clinical study exclusively focused on identifying and validating Parkinson's disease biomarkers.

28 Sep 2010

Genomics obtains worldwide rights to The Garvan Institute of Medical Research's methylation DNA biomarkers

Clinical Genomics Pty. Ltd (Sydney, Australia) and The Garvan Institute of Medical Research (Sydney, Australia) today announced that they have entered into a license agreement in relation to novel biomarkers discovered by scientists at the Garvan Institute. Under the terms of the agreement, Clinical Genomics obtains worldwide exclusive rights to the Garvan's proprietary cancer associated methylation DNA biomarkers for the diagnosis and or treatment of colorectal cancer.

28 Sep 2010

JAMA issue unveils genetic signature of brain cancer

A pair of studies in the July 15 issue of the Journal of the American Medical Association (JAMA) spell out how much closer science has come to unraveling the genetic signature of brain cancer, according to a researcher at the University of Alabama at Birmingham (UAB).

27 Sep 2010

Progenika receives CE Mark approval to market LPLchip in Europe

Progenika Biopharma S.A., a pioneer in the field of personalized medicine, announced today that it has obtained the CE Mark allowing the sale in Europe of its LPLchip(R), the first DNA chip to detect mutations in the lipoprotein lipase (LPL) gene.

27 Sep 2010

Researchers synthesize molecule to block abnormal protein in cancer cells

In the quest to arrest the growth and spread of tumors, there have been many attempts to get cancer genes to ignore their internal instruction manual. In a new study, a team led by Dana-Farber Cancer Institute scientists has created the first molecule able to prevent cancer genes from "hearing" those instructions, stifling the cancer process at its root.

27 Sep 2010

Researchers find stress-activating factors can control genes

Stress has become one of the major disease states in the developed world. Researchers from Dr.Klaus Hansen's group at BRIC, University of Copenhagen, have just shown that external factors can stress our cells through the control of our genes. "We found that stress-activating factors can control our genes by turning on certain genes that were supposed to be silenced.

27 Sep 2010

Hologic receives FDA voting for 3-D digital mammography system

Hologic, Inc., a leading developer, manufacturer and supplier of premium diagnostics products, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, announced that the Radiological Devices Panel (Panel) of the U.S. Food and Drug Administration (FDA) today unanimously voted that Hologic's Pre-Market Approval (PMA) demonstrated both the effectiveness and safety of the Company's Selenia Dimensions three-dimensional (3-D) digital mammography tomosynthesis system, "Selenia Dimensions 3-D."

From Hologic, Inc. 27 Sep 2010

Cellectis bioresearch launches e-store to improve access to meganuclease technology

Cellectis bioresearch, the specialist in genome customization and subsidiary of Cellectis is pleased to announce the launch of its e-store, with approximately one hundred ready-to-use products available for sale online via a new functional and intuitive website.

27 Sep 2010

Gene alteration impacts brain tumor development: Study

The interaction between a network of altered genes appears to play an important role in the development and progression of brain tumors, according to a study in the July 15 issue of JAMA.

27 Sep 2010

Genta commences new tesetaxel Phase 2 clinical trial in advanced bladder cancer

Genta Incorporated today announced that the Company has initiated a new Phase 2 clinical trial of tesetaxel in patients with advanced bladder cancer. Tesetaxel is the leading oral taxane in clinical development. The new trial will be conducted at Memorial Sloan-Kettering Cancer Center, New York, NY, the Kimmel Cancer Center at Jefferson University, Philadelphia, PA, and at least one site in the EU.

24 Sep 2010

Microfluidic Systems ranked #3035 on Inc. 5000

Microfluidic Systems, a privately-held company, announced today that they received an award from Inc. Magazine. The Fourth Annual Exclusive List of America's Fastest-Growing Private Companies—the Inc. 5000 ranked Microfluidic Systems number 3035 with a growth rate of 68%. The list represents the most comprehensive look at the most important segment of the economy—America's independent-minded entrepreneurs.

24 Sep 2010

DNA News and Research

Further Reading

RV262 Phase I study launched to evaluate DNA prime/MVA vector boost vaccine regimen for HIV

GenMark’s eSensor technology selected for Warfarin clinical study

Tel Aviv researchers develop innovative software to analyze and manipulate diseased cells

Japanese Patent Office issues patent for ZIOPHARM Oncology's darinaparsin

Women & Infants Hospital receives $2.1M NIH grant to continue work under COBRE for Perinatal Biology

Onconova Therapeutics to present Ex-RAD radioprotectant data at RRS Annual Meeting

Scientists identify gene associated with common migraines

Study: Genetic ancestry has no influence on how African-Americans with asthma respond to medication

OpGen completes Series B equity financing

Michael J. Fox Foundation launches PPMI clinical study to identify Parkinson's disease biomarkers

Genomics obtains worldwide rights to The Garvan Institute of Medical Research's methylation DNA biomarkers

JAMA issue unveils genetic signature of brain cancer

Progenika receives CE Mark approval to market LPLchip in Europe

Researchers synthesize molecule to block abnormal protein in cancer cells

Researchers find stress-activating factors can control genes

Hologic receives FDA voting for 3-D digital mammography system

Cellectis bioresearch launches e-store to improve access to meganuclease technology

Gene alteration impacts brain tumor development: Study

Genta commences new tesetaxel Phase 2 clinical trial in advanced bladder cancer

Microfluidic Systems ranked #3035 on Inc. 5000

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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