DNA Replication News and Research

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DNA replication, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the reproduction of the complementary strand. Hence, following DNA replication, two identical DNA molecules have been produced from a single double-stranded DNA molecule. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.
Artificial mammalian origin of replication

Artificial mammalian origin of replication

New insights into how genetic mutations arise

New insights into how genetic mutations arise

Bouncing helicases possibly play a preventative role in keeping the genome intact

Bouncing helicases possibly play a preventative role in keeping the genome intact

First time a protein serving as a template for DNA synthesis seen

First time a protein serving as a template for DNA synthesis seen

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

New knowledge into the molecular mechanisms involved in tumor growth

New knowledge into the molecular mechanisms involved in tumor growth

Researchers have pinpointed specific gene and protein over-production in metastatic melanoma

Researchers have pinpointed specific gene and protein over-production in metastatic melanoma

Technique called phylogenetic footprinting reveals new gene regulation system

Technique called phylogenetic footprinting reveals new gene regulation system

Lorus Therapeutics receives patent allowance to protect novel anticancer drug

Lorus Therapeutics receives patent allowance to protect novel anticancer drug

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

Research shows how a virus uses the gene silencing machinery for its own infectious purposes

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

Scientists have uncovered the structure of a network of proteins that help regulate the life cycle of cells

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Hereditary colorectal cancer risk lowered in those without certain gene defect

Hereditary colorectal cancer risk lowered in those without certain gene defect

Method shows how precisely gene expression signals are copied in DNA replication

Method shows how precisely gene expression signals are copied in DNA replication

Researchers show why mutations in a certain few genes, such as the p53 tumor suppressor gene, are found in different cancers

Researchers show why mutations in a certain few genes, such as the p53 tumor suppressor gene, are found in different cancers

DNA weak links may provide clues to cancer biology

DNA weak links may provide clues to cancer biology

Importance of Fbw7 as an emerging tumor suppressor

Importance of Fbw7 as an emerging tumor suppressor

Novel genetic test helps detect mutations that may be missed by conventional DNA test

Novel genetic test helps detect mutations that may be missed by conventional DNA test

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

Patent issued for generating genetically evolved mammalian cells through the regulation of mismatch repair

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA