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Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs.

20 Mar 2024

Watch: Many Americans are unaware of HIV prevention medication

Céline Gounder, KFF Health News' editor-at-large for public health, explained on "CBS Mornings" why many at-risk Americans do not know about medication to prevent HIV infection through sexual contact or do not have access to it.

20 Mar 2024

Metformin boosts appetite-suppressing metabolite, new study finds

Metformin treatment boosts levels of Lac-Phe, an appetite-suppressing metabolite, potentially offering new insights into its mechanism and opening doors for obesity treatments.

19 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

Aston University and Catalent develop faster medicine formulation process

A partnership between Aston University and contract medicine manufacturer Catalent has led to a faster process to identify the best ingredients for optimal medicine formulations, and has been rated as outstanding by Innovate UK.

19 Mar 2024

Understanding schizophrenia through genetics and neural pathways

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person's risk of the disease.

19 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Knitting is beneficial for people with mental health problems, study shows

A study from the University of Gothenburg shows that knitting is beneficial for people living with mental health issues.

19 Mar 2024

Advanced laser imaging illuminates molecular interactions driving lung cancer growth

Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.

19 Mar 2024

Amid mental health staffing crunch, Medi-Cal patients help one another

Three people gathered in a classroom on a recent rainy afternoon listened intently as Derrick Cordero urged them to turn their negative feelings around.

19 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Punitive prenatal drug laws lead to negative health outcomes

Contrary to some claims, laws that criminalize or otherwise punish drug use during pregnancy are more likely to worsen rather than improve health outcomes, according to a paper by researchers at Columbia University Mailman School of Public Health.

18 Mar 2024

Lab-synthesized heparin to transform drug manufacturing

Heparin, the world's most widely used blood thinner, is used during procedures ranging from kidney dialysis to open heart surgery.

18 Mar 2024

Unlocking weight loss through exercise mimicry with metformin

An "anti-hunger" molecule produced after vigorous exercise is responsible for the moderate weight loss caused by the diabetes medication metformin, according to a new study in mice and humans.

18 Mar 2024

Mouse models shed light on the effects of metformin use during pregnancy on offspring

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently.

18 Mar 2024

Implantable temperature sensor detects inflammatory flareups in patients with Crohn's disease

A team of Northwestern University scientists has developed the first wireless, implantable temperature sensor to detect inflammatory flareups in patients with Crohn's disease.

18 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Rare condition post-orgasmic illness syndrome explored in depth

Comprehensive review synthesizes current knowledge on post-orgasmic illness syndrome (POIS), a rare condition marked by a range of symptoms following ejaculation, highlighting the need for further research to understand its causes and develop effective treatments.

17 Mar 2024

BU study reveals key to combating high-risk neuroblastoma

The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers.

15 Mar 2024