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Ocera Therapeutics presents data on prevalence of neurocognitive impairment in cirrhotic patients

Ocera Therapeutics, Inc. presented an analysis of the prevalence of neurocognitive impairment in ambulatory cirrhotic patients. The data came from the screening period of the ASTUTE Study, an ongoing Phase 2b study evaluating the safety and efficacy of AST-120 (spherical carbon adsorbent) in the treatment of mild hepatic encephalopathy (MHE). The poster was presented yesterday at the annual meeting of the European Association for the Study of Liver (EASL) in Vienna, Austria. Efficacy and safety data from the ASTUTE study are expected in the summer of 2010.

17 Apr 2010

MiRNA-21 interferes with Herceptin therapy, says study

Overexpression of a specific type of microRNA can derail treatment by disabling an important molecular brake on breast cancer cell proliferation, according to evidence presented by researchers from The University of Texas M. D. Anderson Cancer Center at the American Association for Cancer Research 101st Annual Meeting 2010.

17 Apr 2010

Federal cancer research is 'at a breaking point,' IOM study finds

Bloomberg: "The government's cancer research network is 'approaching a state of crisis' as waste and inefficiency cause 40 percent of late-stage trials it funds to be abandoned before completion, according to a report released yesterday. The government-funded National Cancer Institute's clinical trials group isn't able to effectively study the benefits of new and current treatments, according to the analysis by the Institute of Medicine.

17 Apr 2010

Endra Life Sciences launches Nexus 128 preclinical photoacoustic CT scanner

Endra Life Sciences today announced the launch of the Nexus 128, a preclinical photoacoustic computed tomography (CT) scanner for small animal imaging. The system is used for simple, fast, non-invasive quantification of tumor vasculature and other physiological parameters for preclinical research.

16 Apr 2010

Research reveals TRPV3 protein as potential new drug target for cancer and skin disorders

New findings about a temperature sensor in the skin could lead to novel approaches to controlling excess hair growth and treating skin cancers.

16 Apr 2010

Cancer Research UK announces launch of new team to co-ordinate children's cancer trials

Birmingham will be at the forefront of developments in childhood cancer research thanks to the launch of a new team which will co-ordinate groundbreaking clinical trials across the UK.

16 Apr 2010

International study evaluates new class of drugs for treating primary biliary cirrhosis

Results of a study presented today at the at the International Liver CongressTM 2010 reveals the effects of a new drug for the treatment of primary biliary cirrhosis, and shows further evaluation is necessary.

16 Apr 2010

Serametrix announces commercial launch of serum test for measuring serum antibodies

Serametrix has announced the commercial launch of a serum test for measuring serum antibodies to the important tumor antigen NY-ESO-1. The test will be offered as a service to drug companies and clinicians for correlative studies, monitoring and potentially predicting patient responses to cancer treatments.

16 Apr 2010

Survey investigates procurement procedures, expenditures and consumption of medical devices

Centralised purchasing of medical devices does not reduce prices and medical devices are often undervalued as analyses focus only on the short-term financial and economic perspectives.

16 Apr 2010

Investment report on Idenix Pharmaceuticals

StockPreacher.com announces an investment report featuring Idenix Pharmaceuticals Inc.. The report includes financial, comparative and investment analyses, and industry information you need to know to make an educated investment decision.

16 Apr 2010

Pharmacyclics to present on Btk and HDAC programs at AACR 2010

Pharmacyclics, Inc. today announced multiple presentations covering its Btk and HDAC programs at the American Association for Cancer Research 2010 Annual Meeting being held April 17-21 in Washington, DC.

16 Apr 2010

Preclinical results of Avila Therapeutics' AVL-181 and AVL-192 presented at EASL Annual Meeting

Avila Therapeutics™, Inc., a biotechnology company developing targeted covalent drugs that treat diseases through protein silencing, presented results of preclinical studies on two of its Hepatitis C Virus protease inhibitors, AVL-181 and AVL-192. These inhibitors, due to their unique mechanism of action with superior selectivity and potency, have potential as best-in-class, pan-genotype HCV therapeutics.

16 Apr 2010

Number of organizations to join in a briefing on health care reform

On May 10, a number of organizations will join in a briefing on health care reform to talk about what would really allow health care to become more affordable and more responsive to the individual rights and choices of Americans.

16 Apr 2010

New study may help devise better treatment strategies for cancer and heart disease

Research led by T. Cooper Woods, PhD, Assistant Professor of Pharmacology and Experimental Therapeutics at LSU Health Sciences Center New Orleans, and Director of the Molecular Cardiology Research Laboratory at Ochsner Clinic Foundation, has identified the mechanism of how a drug commonly used on stents to prevent reclosure of coronary arteries, regulates cell movement which is critical to wound healing and the progression of diseases like cancer.

16 Apr 2010

Findings strengthen promise of SCYNEXIS' SCY-635 for HCV treatment

Drug discovery company SCYNEXIS, Inc. today presented data supporting an impressive resistance profile for SCY-635—a novel, oral cyclophilin inhibitor being studied for the treatment of hepatitis C virus (HCV) infection. In the study, SCYNEXIS demonstrated that the hepatitis C virus required multiple mutations across two separate proteins in order to establish resistance to SCY-635. The majority of HCV drugs on the market and in development require only one targeted viral mutation to establish resistance.

16 Apr 2010

Scientists grow cultured neurons to investigate basic mechanisms of memory

In order to be able to understand complex organs such as the brain or the nervous system, simplified model systems are required. A group of scientists led by the Frankfurt brain researcher Erin Schuman has successfully developed a novel method to grow cultured neurons in order to investigate basic mechanisms of memory.

16 Apr 2010

Promising pharmacokinetic data from Idenix Pharmaceuticals' Phase I study of IDX320 for HCV

Idenix Pharmaceuticals, Inc., a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today reported promising in vitro data for IDX320, an HCV protease inhibitor, demonstrating potent and selective antiviral activity in multiple genotypes, or strains, of the virus.

16 Apr 2010

CombinatoRx's synergistic drug combinations for cancer treatment to be highlighted at AACR 2010

CombinatoRx, Incorporated today announced that preclinical data on its discovery of novel synergistic drug combinations for the treatment of cancer will be highlighted at the 101st Annual meeting of the American Association for Cancer Research 2010, April 17-21, in Washington, DC.

16 Apr 2010

Study: Circadian’s anti-cancer therapy reduces tumour growth in animal models

Circadian Technologies Limited today released data demonstrating that its lead anti-cancer therapeutic, VGX-100, significantly inhibits tumour growth in a variety of different animal models (tumour xenografts) of human cancer.

16 Apr 2010

Researchers say exclusive licensing on genes could hurt patients

The Wall Street Journal reports that Duke University researchers have found in a study published Wednesday that granting "exclusive licenses on individual genes" could hurt patients' chances of pinpointing their risks to develop disease.

16 Apr 2010

Drugs News and Research

Ocera Therapeutics presents data on prevalence of neurocognitive impairment in cirrhotic patients

MiRNA-21 interferes with Herceptin therapy, says study

Federal cancer research is 'at a breaking point,' IOM study finds

Endra Life Sciences launches Nexus 128 preclinical photoacoustic CT scanner

Research reveals TRPV3 protein as potential new drug target for cancer and skin disorders

Cancer Research UK announces launch of new team to co-ordinate children's cancer trials

International study evaluates new class of drugs for treating primary biliary cirrhosis

Serametrix announces commercial launch of serum test for measuring serum antibodies

Survey investigates procurement procedures, expenditures and consumption of medical devices

Investment report on Idenix Pharmaceuticals

Pharmacyclics to present on Btk and HDAC programs at AACR 2010

Preclinical results of Avila Therapeutics' AVL-181 and AVL-192 presented at EASL Annual Meeting

Number of organizations to join in a briefing on health care reform

New study may help devise better treatment strategies for cancer and heart disease

Findings strengthen promise of SCYNEXIS' SCY-635 for HCV treatment

Scientists grow cultured neurons to investigate basic mechanisms of memory

Promising pharmacokinetic data from Idenix Pharmaceuticals' Phase I study of IDX320 for HCV

CombinatoRx's synergistic drug combinations for cancer treatment to be highlighted at AACR 2010

Study: Circadian’s anti-cancer therapy reduces tumour growth in animal models

Researchers say exclusive licensing on genes could hurt patients

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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