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Combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission

Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world.

29 Jul 2005

Beta-blockers 'blot out memories' for sufferers with post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) affects around one in three of people caught up in such events, as the London bombings, and memories can be triggered just by a sound or smell.

29 Jul 2005

Amazing 'smart bomb' drug zaps cancer cells in mice without damaging healthy cells

Scientists say they have developed an anti-cancer 'bomb' which has a similar behavior to a Trojan horse.

28 Jul 2005

Key step in the entry of anthrax toxin into human cells

The work, which grew out of an ongoing effort to produce a better anthrax therapeutic, shows that the protective antigen component of the bacterial toxin plays an active role in transferring the other two components of the toxin through the cell membrane.

28 Jul 2005

Action of dopamine may be particularly important for understanding psychiatric conditions

Duke University Medical Center researchers have discovered a new mechanism by which chronically high levels of the neurotransmitter dopamine exert their effects on the brain.

28 Jul 2005

Valuable clues for rational antimalarial drug design and vaccine development

By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. The findings are reported in the July 29 issue of the journal Cell.

28 Jul 2005

Discovery sheds light on how a low-calorie diet extends lifespan

Mice, rats, worms, flies, and yeast all live longer on a low-calorie diet, which also seems to protect mammals against cancer and other aging-related diseases.

28 Jul 2005

New insight into how protein E75 may control circadian rhythms and metabolic processes

University of Toronto researchers have gained new insight into how a specific protein may control circadian rhythms and metabolic processes, which has implications for treating cholesterol-related diseases.

28 Jul 2005

Anti-inflammatory function of Alzheimer's disease drugs revealed

The mechanism in anti-Alzheimer's disease drugs that inhibits the production of a destructive, inflammation-causing protein in the brain has been revealed by researchers at the Hebrew university of Jerusalem.

28 Jul 2005

Study raises concern about the use of beta blockers for all heart patients

Doubt has been cast on the popular practice of giving most heart patients drugs that reduce the heart's workload before and after major surgery, after new research has raised concerns about it.

28 Jul 2005

Scientists discover genes linked to spread of breast cancer

In new research scientists have identified genes which enable breast cancer cells to spread to the lungs, and the discovery could very well improve diagnosis and treatment of the disease.

28 Jul 2005

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Carbon monoxide, a poisonous gas that kills thousands of Americans every year, could turn out to be a life-saver for patients recovering from organ transplants, strokes or heart attacks, according to new research from the University of Michigan Cardiovascular Center.

28 Jul 2005

Bone marrow may be source of new egg-cell generation

Last year a group of Massachusetts General Hospital (MGH) researchers announced surprising findings that female mice - contrary to longstanding theories of mammalian reproductive physiology - retained the ability to make new egg cells or oocytes into adulthood.

27 Jul 2005

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Imagine a cancer drug that can burrow into a tumor, seal the exits and detonate a lethal dose of anti-cancer toxins, all while leaving healthy cells unscathed.

27 Jul 2005

Infectious diseases pose a serious threat to the nation's public health

Infectious diseases pose a serious threat to the nation's public health. Today, experts addressed key developments to the current and future outlook of infectious diseases, highlighting adolescent immunizations, outbreaks and epidemics of infectious diseases, antimicrobial resistance and new developments in HIV medicine, at a press conference sponsored by the National Foundation for Infectious Diseases (NFID).

27 Jul 2005

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Opiates appear to better "ameliorate the withdrawal, facilitate feeding and potentially reduce the likelihood of seizures," according to two new systematic reviews done by David Osborn, a neonatologist at the Royal Prince Alfred Hospital in Sydney, Australia, and colleagues.

26 Jul 2005

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

The effectiveness of chemotherapy in patients with advanced breast cancer can be evaluated earlier by using 18F-FDG positron emission tomography (PET) imaging over other conventional imaging procedures, according to an article in the July issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

26 Jul 2005

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

In research published in the August issue of Free Radical Biology and Medicine, U of T pharmacy and pharmacology professor Peter Wells and his colleagues determined that exposing pregnant mice only once to methamphetamine led to delivery of offspring with long-term neurodevelopmental problems, including reduced motor co-ordination.

26 Jul 2005

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

The study found that almost three fourths of those 80 years and older have hypertension -- blood pressure greater than 140 systolic over greater than 90 diastolic. Fewer than 10 percent have "normal" blood pressure levels -- less than 120 systolic over less than 80 diastolic.

26 Jul 2005

GenoMed submits 50th provisional patent application

GenoMed announced today that the Company has submitted its 50th provisional patent application, a major milestone in any development stage company. GenoMed has so far been awarded two patents, one for treating acute kidney failure without dialysis, and another for hastening lung maturation in prematurely born infants.

26 Jul 2005

Drugs News and Research

Combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission

Beta-blockers 'blot out memories' for sufferers with post-traumatic stress disorder

Amazing 'smart bomb' drug zaps cancer cells in mice without damaging healthy cells

Key step in the entry of anthrax toxin into human cells

Action of dopamine may be particularly important for understanding psychiatric conditions

Valuable clues for rational antimalarial drug design and vaccine development

Discovery sheds light on how a low-calorie diet extends lifespan

New insight into how protein E75 may control circadian rhythms and metabolic processes

Anti-inflammatory function of Alzheimer's disease drugs revealed

Study raises concern about the use of beta blockers for all heart patients

Scientists discover genes linked to spread of breast cancer

Carbon monoxide could turn out to be a life-saver for patients recovering from organ transplants

Bone marrow may be source of new egg-cell generation

Cancer biology, pharmacology and engineering combine to create cancer smart bomb

Infectious diseases pose a serious threat to the nation's public health

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

Single prenatal dose of methamphetamine enough to cause long-term neurodevelopmental problems in babies

Controlling high blood pressure in individuals age 80 years and older has become a major national health problem

GenoMed submits 50th provisional patent application

Drug Discovery - Second Edition eBook

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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