Dysplasia News and Research

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Dysplasia is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

Bexarotene shows promise in cancer treatment.

Researchers at Washington University School of Medicine in St. Louis now report that a compound related to vitamin A shows promise in preventing or slowing tumor growth in mice prone to lung cancer. The compound, called bexarotene, doesn't cause the severe skin irritations that have limited the use of other vitamin A derivatives in cancer therapies.

18 Jan 2006

University of Alberta researchers pioneer gene therapy to restore alveoli and lung capillaries in damaged rat lungs

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.

13 Nov 2005

Cervical cancer control program increases rate of follow-up

Low-income women with abnormal Pap tests who participated in a program that combines screening and treatment in one visit had a higher rate of treatment and follow-up than women who did not participate, according to a study in the November 2 issue of JAMA: The Journal of the American Medical Association.

3 Nov 2005

Research on cartilage erosion and bone abnormalities

While characteristic of osteoarthritis (OA), a degenerative joint disease that affects some 20 million Americans, cartilage erosion and bone abnormalities are also associated with many rare hereditary conditions.

3 Oct 2005

Helix receives approval to conduct a clinical trial of Topical Interferon Alpha-2b in Sweden

Helix BioPharma today announced that it has received approval from Sweden's drug regulatory authority, the Medical Products Agency (MPA), to conduct a Phase II clinical trial of Topical Interferon Alpha-2b in patients with ano-genital warts (condylomata acuminata), who are positive for infection with the human papilloma virus (HPV).

12 Sep 2005

Toluidine blue dye reveals oral cancers

A team of Canadian scientists may have discovered a way to use a simple dye as a litmus test to identify abnormal areas of the mouth that may become cancers.

1 Sep 2005

MDCT arthrography is an accurate method for assessing cartilage loss in patients with hip dysplasia

MDCT arthrography is an accurate method for assessing cartilage loss in patients with hip dysplasia and may be more reliable than MRI in such instances, says a new study by researchers from Osaka University Medical School in Japan.

4 Aug 2005

Helix opens additional sites for its Topical Interferon Alpha-2b Phase II clinical study

Helix BioPharma announced today the opening of two additional German sites for the Phase II clinical trial of its Topical Interferon Alpha-2b product at the Charité Berlin, one of the largest university hospitals in Europe.

2 Jun 2005

Reconstruction of the lower jaw with a fibula autotrasplant

The University Hospital of the University of Navarra has carried out a complicated surgical operation on a child who had a particularly large benign tumour located in the mandibular region. The procedure involved the extraction of the lower jaw and its substitution by a bone transplant from the fibula of the patient.

10 May 2005

A shallow hip socket predicts osteoarthritis of the hip

Long-term study suggests moderate acetabular dysplasia, a developmental condition of hip instability, as an independent risk factor for the disease.

2 Mar 2005

Researchers attack cervical cancer

As more and more promising results of clinical trials on vaccination against human papillomaviruses are published, the more likely it becomes that an HPV vaccine will be the first licensed immunization against a sexually transmitted disease.

17 Jan 2005

Premature infants with lung disease may continue to require replacement substance to ease breathing

Physicians have known for decades that many premature babies suffer respiratory problems stemming from insufficiency of a lung substance called surfactant during their first few weeks of life.

20 Nov 2004

Obese women at greater risk of colorectal cancer

New study findings show a high body mass index (BMI) among women is a more significant risk factor for colorectal neoplasia than for men.

1 Nov 2004

Pacemakers and defibrillators can be safe for use in magnetic resonance imaging machines

In animal and laboratory studies, scientists at Johns Hopkins have shown that modern, implanted heart assist devices - such as pacemakers and defibrillators - can be safe for use in magnetic resonance imaging (MRI) machines

3 Aug 2004

Method of producing exact models of skull defects which enable technicians to create exactly matching titanium plates

The work of a student at the University of Ulster has had a direct effect on the treatment of patients requiring head and facial surgery.

1 Jul 2004

Scientists believe that the dog genome holds a wealth of information that will benefit human health

Recently completed genetic analysis reveals that half of the more than 300 inherited canine disorders — including a number of cancers — resemble specific diseases of man; many scientists believe that the dog genome holds a wealth of information that will benefit human health.

20 May 2004

Cervical Dysplasia treatment linked to water breaking too early

Two treatments for removing precancerous tissue from the cervix are associated with an increased risk of preterm delivery (delivery before 37 weeks gestation) caused by the pregnancy complication known as preterm premature rupture of membranes (PPROM).

5 May 2004

Researchers tap modified plant viruses to ward off cervical cancer-causing infections

New vaccinations to prevent infections that lead to cervical cancer and targeted therapeutics aimed at breast cancer were examples of research highlights presented by scientists today at the 95th Annual Meeting of the American Association for Cancer Research. Scientists described advances that feed into the drug development 'pipeline,' and show strong promise for controlling existing tumors or addressing the pathogen that causes tumors.

29 Mar 2004