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UConn chemists develop new antibiotic that can find and kill tuberculosis bacteria

Tuberculosis is a sneaky disease. The bacteria hide from antibiotics inside the very immune cells that are supposed to kill them, making treatment long and difficult. But in the November issue of ACS Infectious Diseases, UConn chemists report a new antibiotic that can find and kill tuberculosis bacteria where they hide.

4 Oct 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Antibiotic resistance in cystic fibrosis linked to decreased microbial diversity and pulmonary function

A defective gene causes thick, sticky mucus to build up in the lungs of patients with cystic fibrosis. There, it traps bacteria, causing patients to develop frequent lung infections that progressively damage these vital organs and impair patients' ability to breathe.

27 Sep 2018

Research reveals three-dimensional structure of membrane channel that controls blood pressure

New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure.

26 Sep 2018

Tomocube introduces new holotomography microscope for live cell imaging

A novel optical microscope utilizing diffraction tomography to generate 3D holographic images of unlabelled live cells is now available from Tomocube. Called HT-1, the new microscope delivers quantitative nanoscale, real-time, dynamic images of individual living cells quickly and simply without any sample preparation.

From Tomocube Inc. 25 Sep 2018

Salk Institute researchers uncover molecular structure of RNA-based CRISPR system

Over the past several years, CRISPR-Cas9 has moved beyond the lab bench and into the public zeitgeist. This gene-editing tool CRISPR-Cas9 holds promise for correcting defects inside individual cells and potentially healing or preventing many human ailments.

20 Sep 2018

Zika virus vaccine shows promise for treatment of fatal glioblastoma

An international team of researchers has successfully deployed a Zika virus vaccine to target and kill human glioblastoma brain cancer stem cells, which had been transplanted into mice.

18 Sep 2018

Researchers use CRISPR to identify gene that helps cells resist flavivirus infection

UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.

18 Sep 2018

New research shows evidence of soot from polluted air in placentas

Evidence of tiny particles of carbon, typically created by burning fossil fuels, has been found in placentas for the first time, in new research presented today at the European Respiratory Society International Congress.

17 Sep 2018

Research shows pollution is reaching the placenta

The evidence of air pollution – the soot and the fumes, has been seen in the lungs till date. In a new study, for the first time, the evidence of air pollution is seen in the placenta of a pregnant women.

16 Sep 2018

ZEISS launches new field emission scanning electron microscope

ZEISS introduces its new field emission scanning electron microscope ZEISS GeminiSEM 450. The instrument combines ultrahigh resolution imaging with the capability to perform advanced analytics while maintaining flexibility and ease-of-use.

From Carl Zeiss AG 14 Sep 2018

Thermo Fisher Scientific and Diamond collaborate to launch new cryo-EM capability for use in life sciences industry

An agreement to launch a new cryo-EM capability for use in the life sciences industry sector by Thermo Fisher Scientific, one of the world leaders in high-end scientific instrumentation, and Diamond Light Source, the UK’s national synchrotron and one of the most advanced scientific facilities in the world, was announced today at the official opening of the new national electron bio-imaging center at Diamond.

From Thermo Fisher Scientific – Electron Microscopy Solutions 14 Sep 2018

New discovery overturns centuries of thought about nature of kidney stones

A geologist, a microscopist and a doctor walk into a lab and, with their colleagues from across the nation, make a discovery that overturns centuries of thought about the nature and composition of kidney stones.

14 Sep 2018

Bacteria in the gut found to produce electricity

Researchers have discovered hundreds of bacterial species, including those in the human gut, that can generate electricity.

13 Sep 2018

Measuring nanocrystal length and thickness in just 40 minutes analysis time

Postnova Analytics reports on how Asymmetrical Flow Field Flow Fractionation coupled to Multi Angle Light Scattering (AF4-MALS) has been successfully used to characterize a polydisperse cellulose nanocrystal for size and thickness in just 40 minutes analysis time.

From Postnova Analytics 11 Sep 2018

New research illuminates another significant culprit of traffic-related air pollution

Everyone knows that cars contribute to air pollution. And when most people consider the source, exhaust is usually what comes to mind.

11 Sep 2018

Researchers use virtual reality goggles to study human anatomy

Tucked away in the back room of a Johns Hopkins research building, a computer hums quietly at a seemingly modest setup of a desktop and a pair of goggles.

6 Sep 2018

Scientists introduce bioinspired enzyme model with redox switch

Coupled oxygen transfer and electron transfer reactions that use cofactors are enzymatic reactions of crucial significance to all lifeforms from bacteria to vertebrates. In the European Journal of Inorganic Chemistry, scientists have introduced a model for the enzyme sulfite oxidase.

28 Aug 2018

VTCRI study may disrupt conventional understanding about how electrical activity travels in the heart

Scientists at the Virginia Tech Carilion Research Institute have found evidence that may disrupt conventional understanding about how electrical activity travels in the heart -; a discovery that potentially can lead to new insight into medical problems such as heart arrhythmia and sudden cardiac death.

27 Aug 2018

Changes in TRPV3 genes may have helped mammoths withstand lower temperatures

Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain.

25 Aug 2018