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Research provides insight into how two stands of double helix separate during replication

Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated once and only once.

24 Oct 2017

Measuring biological samples using SNAP

My group is interested in host pathogen interaction and we mainly focus on how bacteria enter cells. In essence, the idea is that if you can prevent bacteria from entering cells, then you will prevent illness.

From Bruker Nano Surfaces and Metrology 24 Oct 2017

New vaccine for pneumonia holds promise to save thousands of lives

In 2004, pneumonia killed more than 2 million children worldwide, according to the World Health Organization. By 2015, the number was less than 1 million.

20 Oct 2017

Researchers use powerful X-ray beams for ‘navigational map view’ of mouse brain

If brain imaging could be compared to Google Earth, neuroscientists would already have a pretty good "satellite view" of the brain, and a great "street view" of neuron details.

17 Oct 2017

Researchers identify strategies to mitigate disturbed axonal transport in ALS patients

A team of researchers at VIB and KU Leuven used stem cell technology to generate motor neurons from ALS patients carrying mutations in FUS. They found disturbed axonal transport in these motor neurons, but also identified genetic and pharmacological strategies that mitigate this defect.

17 Oct 2017

RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

Study helps understand basic mechanisms of mitochondrial DNA maintenance

Researchers at the University of Eastern Finland have discovered a novel mechanism safeguarding mitochondrial DNA. The study, published in PNAS earlier this week, was carried out in close collaboration with research groups from CBMSO in Madrid, Spain, and Umeå University in Sweden.

13 Oct 2017

New serotypes of Zika virus could appear in near future, researcher cautions

Zika virus is mutating so fast in Brazilian patients that different serotypes of the pathogen could appear in the near future, as is already the case with dengue virus. This would hinder the production of a vaccine and impair the effectiveness of the diagnostic tests already developed.

10 Oct 2017

Researchers discover promising alternative to open fetal surgery for spina bifida repair

Researchers from Children's Hospital Colorado and the University of Colorado Anschutz Medical Campus recently discovered a promising alternative to open fetal surgery for spina bifida repair.

5 Oct 2017

ATA’s informative symposia to focus on recent advances in thyroid research

The 87th Annual Meeting of the American Thyroid Association (ATA), taking place October 18‒22, 2017, in Victoria, British Columbia, will offer informative symposia presented by pioneering investigators and key opinion leaders.

4 Oct 2017

Impairing critical partnership between brain cells can lead to Alzheimer's disease

Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration. The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

30 Sep 2017

Researchers develop new surgical screws from human bone material

To heal broken bones using medical help, the surgical method of choice for decades have been metal screws, mainly made of titanium or stainless steel. During and after the healing process, these metal screws are seen by the body as disturbing foreign bodies and often have to be removed in a further unpleasant surgical intervention.

30 Sep 2017

Surgical screws being developed from donated human bone material

Biomechanics from TU Graz, are developing surgical screws from donated human bone material for foot and jaw surgery together with surgebright, a start-up from Linz, Austria.

28 Sep 2017

Research reveals novel mechanism of ribosome dimerization using cryo-electron microscopy

Antibiotics are the most common medication used to treat microbial infections. Many antibiotics target intracellular bacterial ribosomes - cellular factories that synthesize proteins - which are essential for bacterial survival and proliferation.

28 Sep 2017

Researchers explore what happens during break down of nerve cells

A stroke is just one example of a condition when communication between nerve cells breaks down. Micro-failures in brain functioning also occur in conditions such as depression and dementia. In most cases, the lost capacity will return after a while.

27 Sep 2017

Researchers use gene therapy to restore hearing and balance in mouse model of Usher syndrome

Hearing loss, sometimes associated with other disorders such as balance defects, is the most common sensory deficit, affecting more than 280 million people worldwide, according to WHO. In France, one child in 700 is born with severe or profound hearing loss, and one in every 1,000 will lose their sense of hearing before adulthood.

22 Sep 2017

Researchers identify exosomes as missing link to insulin resistance in type 2 diabetes

Chronic tissue inflammation resulting from obesity is an underlying cause of insulin resistance and type 2 diabetes. But the mechanism by which this occurs has remained cloaked, until now.

21 Sep 2017

UTSW receives $34 million CPRIT award for cancer research and faculty recruitment

The Cancer Prevention and Research Institute of Texas has awarded UT Southwestern researchers more than $34 million for cancer research and faculty recruitment, including support for programs in pancreatic cancer, lung cancer, breast cancer, and melanoma.

19 Sep 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

Research highlights problems with titanium based nanoparticles in joint implants

A team of researchers from Mayo Clinic have found that that Titanium Dioxide (TiO2) nanoparticles that are present in bone implants may be causing harm by impairing bone formation and interfering with resorption at the site of repair. This can lead to loosening of the implants and pain.

15 Sep 2017