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Study offers new insights for vaccine development to prevent RSV disease

In healthy adults, RSV, or respiratory syncytial virus, feels like the common cold with a runny nose, chest congestion and cough.

27 Mar 2019

Shaping new treatments for tuberculosis

To commemorate World TB Day, a Special Collection has been released by PLOS Medicine containing a series of articles that articulate the essential new steps in clinical research that will pave the way for the development of tomorrow's optimal treatment for all forms of tuberculosis.

25 Mar 2019

Hidden differences between pathology of CTE and Alzheimer's disease discovered

An international team of scientists at Indiana University School of Medicine, University of Kansas and the U.K. Medical Research Council have dismantled the belief that Alzheimer's disease and Chronic Traumatic Encephalopathy have identical pathology.

22 Mar 2019

Study finds previously unknown mechanism for microbes to save energy in lean times

In favorable conditions, many bacteria propel themselves to food sources and other sites of interest using whip-like molecular propellers known as flagella.

20 Mar 2019

New chromatography technique may improve our understanding of retroviral infections

Researchers have devised a two-step chromatography method that can isolate enveloped virus-like particles (VLPs) and extracellular vesicles (EVs) for analysis.

11 Mar 2019

Electroceutical bandages can help heal wounds faster

Bandages infused with electricity can help heal wounds faster than typical bandages or antibiotics--but for years, researchers have not really understood why.

7 Mar 2019

Biophysicists visualize atomic-level dynamics of largest protein-degrading machine

Protein dynamics are essential for their functions. Protein nanomachines made of multiple protein molecules are highly dynamics during their actions on their functional targets, sometime called substrates.

26 Feb 2019

New green, economical way achieves key organic synthesis via catalyst synergy

In organic chemistry, discovering new reactions is one thing, but to carry them off efficiently is quite another. Carbon-carbon bond-forming is at the heart of organic synthesis, allowing us to stitch together diverse functional groups into an endless array of useful compounds.

26 Feb 2019

Scientists discover trigger that turns strep infections into devastating disease

Houston Methodist infectious disease scientists have discovered a previously unknown trigger that turns a relatively run-of-the-mill infection into a devastatingly ravenous, flesh-eating disease.

18 Feb 2019

MUSC researchers discover new mechanism for a class of anti-cancer drugs

Researchers at the Medical University of South Carolina reveal a novel binding site for a class of anti-cancer drugs known as E1 inhibitors. This finding could lead to the design of more efficient E1 inhibitors.

15 Feb 2019

Blood clot discovery could lead to development of better treatments for blood diseases

Scientists have discovered new ways in which the body regulates blood clots, in a discovery which could one day lead to the development of better treatments that could help prevent and treat conditions including heart diseases, stroke and vascular dementia.

15 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

A new step in decoding cell-to-cell communication

Cells in our bodies have the ability to speak with one another much like humans do. This communication allows organs in our bodies to work synchronously, which in turn, enables us to perform the remarkable range of tasks we meet on a daily basis.

1 Feb 2019

Scientists create visual guide to help identify and control Asian longhorned ticks

Rutgers researchers and other scientists have created a visual guide to help identify and control the Asian longhorned tick, which transmits a fatal human disease in its native countries and threatens livestock in the United States.

30 Jan 2019

NIH researchers discover that anti-flu antibodies can inhibit two different viral proteins

Researchers from the National Institutes of Health have discovered that antibodies that may form the basis of a universal flu vaccine inhibit a second viral protein in addition to the one that they bind.

25 Jan 2019

Excessive suppression of GSK3 enzyme can trigger renal failure, finds study

Scientists have identified an enzyme that is a "master regulator" of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals.

24 Jan 2019

Clinical testing begins for temperature-stable experimental tuberculosis vaccine

Vaccinations have begun in a Phase 1 human clinical trial testing a freeze-dried, temperature-stable formulation of an experimental tuberculosis vaccine candidate.

23 Jan 2019

New fabric can harvest body heat to power small wearable microelectronics

Many wearable biosensors, data transmitters and similar tech advances for personalized health monitoring have now been "creatively miniaturized," says materials chemist Trisha Andrew at the University of Massachusetts Amherst, but they require a lot of energy, and power sources can be bulky and heavy.