Encephalomyelitis News and Research

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AI and synthetic patients could make early diagnosis of chronic fatigue syndrome more feasible

Between 17 and 24 million people worldwide suffer from chronic fatigue syndrome, a deeply debilitating and difficult-to-diagnose condition.

21 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Decoding long COVID, pathophysiology, epidemiology, diagnosis, and management

Comprehensive review unravels the complexities of long COVID, spanning pathophysiology to management strategies, and underscores the need for targeted therapies and early diagnosis.

5 Nov 2023

Brain clues in the battle against long COVID: study pinpoints neuroinflammation

The relationship between circulating markers of vascular dysfunction and neuroinflammation.

25 Oct 2023

Aureane-type sesquiterpene tetraketides hold great promise in treating IL-17A-mediated immune diseases

This new article publication from Acta Pharmaceutica Sinica B, discusses aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity.

15 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Researchers use cryo-EM and molecular dynamics to reveal conformational changes in the spike proteins of human coronavirus HKU1 upon binding with a receptor. Findings unveil the complexity of beta coronavirus attachment, suggesting a more intricate mechanism of host cell invasion than previously understood.

8 Oct 2023

Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.

28 Sep 2023

Long COVID's biological blueprint: new study offers promising insights

Researchers designed a cross-sectional study to investigate the biological underpinnings of “Long COVID”, the post-acute infection syndrome triggered by SARS-CoV-2.

27 Sep 2023

How does long covid impact the school experiences of children and young people?

The impact of long covid on school experiences.

26 Sep 2023

Could creatine supplementation be the answer to post-COVID-19 fatigue?

In a recent study published in the journal Food Science & Nutrition, researchers investigated creatine supplementations as a potential intervention strategy to attenuate the clinical symptoms of post-COVID-19 fatigue syndrome.

22 Sep 2023

Mount Sinai secures $6.2 million grant to expand the Cohen Center for Recovery From Complex Chronic Illnesses

Mount Sinai's Department of Rehabilitation and Human Performance has announced a $6.2 million grant from the Steven & Alexandra Cohen Foundation.

20 Sep 2023

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Tiziana Life Sciences Ltd. (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced acceptance of a publication, “Nasal Administration of anti-CD3 monoclonal antibody (mAb) ameliorates disease in a mouse model of Alzheimer’s disease”, in the preeminent journal, Proceedings of the National Academy of Sciences (PNAS), that supports foralumab’s mechanism as a potential treatment for Alzheimer’s disease (AD), a difficult-to-treat neuroinflammatory disease.

9 Sep 2023

Biomarkers unveil insights into post-COVID-19 syndrome variability

Researchers studied a prospective observation cohort of patients with post-coronavirus disease 2019 syndrome.

1 Sep 2023

ME/CFS and Long COVID: A closer look at the similarities and differences

While myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are not the same disease, they appear to have features of overlapping biological and symptomatic presentations.

23 Aug 2023

Research focuses on Long Covid patient's legs turning blue after 10 minutes of standing

An unusual case of a Long Covid patient's legs turning blue after 10 minutes of standing highlights the need for greater awareness of this symptom among people with the condition, according to new research published in the Lancet.

11 Aug 2023

The long-term effects of SARS-CoV-2 infection on T cell activation: autoimmune disorders and endothelial cell dysfunction

Authors explored the impact of SARS-CoV-2 on thymus (T) cell activation.

1 Aug 2023

RSV vaccines for older adults: 2023 ACIP recommendations

A recent report published in Morbidity and Mortality Weekly Report provided clinical guidance on Respiratory syncytial virus (RSV) vaccines for adults ≥60 years.

1 Aug 2023

NIAID funds research to better understand Post-treatment Lyme Disease Syndrome

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded five projects for research to better understand Post-treatment Lyme Disease Syndrome (PTLDS), which is a collection of symptoms, such as pain, fatigue, and difficulty thinking or "brain fog," which linger following standard treatment for Lyme disease.

21 Jul 2023

m6A modification as a potential therapeutic target for autoimmune diseases

N6-methyladenosine (m6A) is the most extensive studied RNA modification across various species, and the important effect of m6A modification in immune system has been revealed in distinct contexts, including mRNA metabolism, cell differentiation, proliferation and response to stimulation.

14 Jul 2023