Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Managing menopause: The 2023 toolkit for healthcare practitioners

The authors of the revised 2023 Toolkit extracted key recommendations from professional guidelines and positions as well as consensus statements on menopause and related conditions that have emerged since 2014.

1 Nov 2023

Study shows high prevalence of thyroid cancer among transgender female veterans

A new study by UC Davis Health endocrinology researchers has shown a high prevalence of thyroid cancer among transgender female veterans.

25 Oct 2023

Ketogenic diet boosts IVF success for women with PCOS, study reveals

A recent study in the journal "Nutrients" investigated the effects of dietary interventions, including the Mediterranean diet (MD) and a very low-calorie ketogenic diet (VLCKD), on overweight or obese women with polycystic ovarian syndrome (PCOS) undergoing in vitro fertilization (IVF).

24 Oct 2023

Study explores sex-specific effects in Alzheimers disease pathology

The role of biological sex in the development and progression of Alzheimer's Disease (AD).

19 Oct 2023

Female sex hormones play significant role in Alzheimer's disease

Alzheimer's disease disproportionately affects women, who represent about two-thirds of those diagnosed with the late-onset type of the disease.

17 Oct 2023

Study links physiologically assessed hot flashes with heightened systemic inflammation

Hot flashes have long been known to be linked to a number of adverse health effects. Emerging data suggests an association between them and cardiovascular disease.

27 Sep 2023

Can fluctuating reproductive hormone levels cause mental health conditions?

The association between mental health and fluctuations in reproductive hormone levels.

11 Sep 2023

Rethinking menopause: Experts call for individualized treatment and more research

A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. The article also discusses various therapeutic interventions, from hormone therapy to alternative medicines, and their efficacy in managing menopausal symptoms.

7 Sep 2023

The efficacy and safety of anti-androgens in the management of hormonal and clinical features of PCOS

The safety and efficacy of anti-androgens in managing polycystic ovary syndrome (PCOS).

1 Sep 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Medi-Cal covers gender-transition treatment, but getting it isn’t easy

From an early age, Pasha Wrangell felt different. Societal expectations of boys, and many characteristics of masculinity, did not match how Wrangell felt inside.

10 Aug 2023

High-level BPA exposure may affect male fertility

Scientists discuss the effect of bisphenol A on human male fertility.

9 Aug 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Could alpha lipoic acid treat polycystic ovary syndrome?

Authors analyzed the efficacy of alpha lipoic acid (ALA) in treating polycystic ovary syndrome (PCOS).

24 Jul 2023

How does physical activity impact fertility?

Researchers reviewed existing literature to understand the effect of exercise on fertility.

6 Jul 2023

Transgender adolescents rarely chose to discontinue gender-affirming hormone therapy, finds study

A three-year-long retrospective cohort study of a single Atlanta hospital's patient population found transgender and gender-diverse teenagers rarely chose to discontinue gender-affirming hormone therapy, according to a study being presented Sunday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

18 Jun 2023

Study offers a new perspective on the reproductive toxicity of phthalates

Prenatal exposure to chemicals called phthalates, which are used in hundreds of products, may lead to hormonal changes in females that could affect their future fertility, suggests a study in mice being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2023

Women taking oral estrogen therapy more likely to develop high blood pressure

Women ages 45 years and older taking estrogen hormone therapy in pill form were more likely to develop high blood pressure than those using transdermal (topical, applied to the skin) or vaginal formulations, according to new research published today in Hypertension, a peer-reviewed American Heart Association journal.

5 Jun 2023

Obesity strikes below the belt: Study reveals link between obesity and male infertility

The influence of obesity on male fertility is still under debate. In the present investigation, researchers scrutinized semen samples from both obese individuals and those of normal weight. The aim was to explore the relationship between obesity, the length of sperm telomeres, levels of mRNA associated with autophagy, and diverse semen characteristics.

29 May 2023

How estrogens and progesterone present in human milk impact infants' health

Review examines the presence of estrogens and progesterone in human milk and their potential impact on infant growth and health. It explores factors influencing hormone levels and provides insights for effective intervention strategies.

18 May 2023