Estradiol News and Research

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Estradiol is a sex hormone. Mislabelled the "female" hormone, it is also present in males; it represents the major estrogen in humans. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs including the bones.

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

Vitamin B12 boosts testosterone levels in men with infertility

Research finds that higher serum vitamin B12 levels are associated with improved testosterone concentrations in men with infertility, but no impact on other reproductive hormones.

30 Sep 2024

Hormonal markers predict treatment response in alcohol use disorder

A new study reveals hormonal and biochemical factors that affect alcohol dependence (also known as Alcohol Use Disorder), suggesting that men and women with alcohol problems may benefit from different treatments.

22 Sep 2024

Research reveals only a few brain regions remain untouched by transition to motherhood

Research shows pregnancy triggers neuroanatomical changes in the brain, with decreased cortical volume and increased white matter integrity over gestation.

17 Sep 2024

Menopause linked to increased risk of cognitive issues

With more than 24 million people globally living with dementia without a cure in sight, there is a lot of focus on ways to prevent and delay cognitive impairment. A new study suggests that severe menopause symptoms such as hot flashes and depression can negatively affect cognitive function in postmenopausal women. Results of the study are published online today in Menopause, the journal of The Menopause Society.

14 Aug 2024

New AI method accurately predicts male infertility from hormone levels, bypassing need for semen analysis

Study investigates the accuracy of an AI screening method for male infertility based on serum hormone levels, offering a non-invasive alternative to traditional semen analysis.

4 Aug 2024

Breakthrough humanized mouse model offers new insights for immunotherapy development

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling.

5 Jul 2024

Effects of time-restricted eating and calorie restriction on sex hormones

The effects of time-restricted eating (TRE) and caloric restriction (CR) on sex hormones.

14 Jun 2024

Does cannabis use cause erectile dysfunction?

Study found no causal link between cannabis use and erectile dysfunction or changes in sex hormone levels using Mendelian randomization analysis.

7 Jun 2024

Cervix organ chips pave the way for next-generation studies on host-microbiome interactions

A group of researchers developed human Cervical Organ Chips to model the cervical interface.

4 Jun 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Clomiphene and dexamethasone boost fertility in PCOS patients

Combined clomiphene and dexamethasone treatment improves pregnancy and ovulation rates in PCOS patients, with minimal adverse effects. Further research is needed to optimize dosage and duration.

22 May 2024

High testosterone levels in older men associated with greater risk of atrial fibrillation

Researchers investigated whether higher endogenous testosterone levels increase atrial fibrillation (AF) risk among healthy older males.

2 May 2024

The complex relationship between obesity and male reproductive function

Authors have analyzed current evidence on the impact of obesity on the male reproduction system.

9 Apr 2024

Managing migraines and menopausal symptoms to reduce cardiovascular risks in middle-aged women

14 Feb 2024

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

Genetics of estrogen production linked to endometrial cancer risk in postmenopausal women

A study in eBioMedicine identifies genetic factors regulating blood estrone levels in postmenopausal women, linking specific genetic loci to an increased risk of endometrial cancer, highlighting the role of non-ovarian estrogen production in cancer development.

11 Feb 2024