Fallopian Tube News and Research

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Cancer cells hijack communication between fallopian tube and ovary to drive tumor growth

New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule hormone, from the ovary.

10 Oct 2018

Scientists unravel the mystery behind ovarian cancer with high-grade serous carcinoma

More than two-thirds of women with ovarian cancer have high-grade serous carcinoma. Up to 90 percent of HGSCs are not detected until they are beyond the ovaries or fallopian tubes, at which point it may not be possible to fully remove the tumor.

14 Aug 2018

PMDA approves use of LYNPARZA in patients with BRCA-mutated breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that Japan's Pharmaceuticals and Medical Devices Agency has approved LYNPARZA tablets for use in patients with unresectable or recurrent BRCA-mutated, human epidermal growth factor receptor 2 -negative breast cancer who have received prior chemotherapy.

2 Jul 2018

Ovarian cancer therapy may help treat patients with aggressive pancreatic cancer

A targeted therapy that has shown its power in fighting ovarian cancer in women including those with BRCA1 and BRCA2 mutations may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options.

18 May 2018

California lawmakers seek reparations for people sterilized by the state

Rosie Zaballos liked to host playtime tea parties and was sweet to everyone she met. But her older brother worried that the 16-year-old, whom her family described as “a little slow,” might someday become pregnant.

25 Apr 2018

FDA grants approval for first drug to treat inherited breast cancer

The U.S. Food and Drug Administration today expanded the approved use of Lynparza (olaparib tablets) to include the treatment of patients with certain types of breast cancer that have spread (metastasized) and whose tumors have a specific inherited (germline) genetic mutation, making it the first drug in its class (PARP inhibitor) approved to treat breast cancer, and it is the first time any drug has been approved to treat certain patients with metastatic breast cancer who have a "BRCA" gene mutation.

15 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Pregnancies after failed outpatient sterilization procedures more likely to result in live births

While the risk of pregnancy is low after female sterilization procedures, 60 percent of pregnancies that do occur result in a live birth, according to a new study.

11 Jan 2018

Genomic roots of ovarian tumors may arise in fallopian tubes, study suggests

Some scientists have suspected that the most common form of ovarian cancer may originate in the fallopian tubes, the thin fibrous tunnels that connect the ovaries to the uterus.

24 Oct 2017

Trial confirms standard three-week dosing of chemotherapy as first line treatment in ovarian cancer

European women with ovarian cancer can safely stick to the standard three-week dosing schedule for paclitaxel rather than boosting up to a weekly dose-dense regimen, according to results of the phase III ICON8 trial to be presented at the ESMO 2017 Congress in Madrid.

4 Sep 2017

Researchers identify new gene mutation that leads to infertility in women

It has been estimated that more than 80 million people in the world have an unfulfilled desire to have children. But for every 10th couple, the reasons therefor remain unclear.

28 Mar 2017

FDA approves new maintenance therapy for recurrent cancers

The U.S. Food and Drug Administration today approved Zejula (niraparib) for the maintenance treatment (intended to delay cancer growth) of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer, whose tumors have completely or partially shrunk (complete or partial response, respectively) in response to platinum-based chemotherapy.

27 Mar 2017

Immobilisation after intrauterine insemination has no beneficial effect on pregnancy rates in women

Despite the positive results of small studies and a widely held belief in its benefit, the practice of keeping female patients immobilised after intrauterine insemination has no beneficial effect on pregnancy rates, according to results of a large randomised study presented here at the Annual Meeting of ESHRE in Helsinki.

5 Jul 2016

Study examines role of HOX genes in ovarian cancer resistance

A new UK study has identified a gene signature that predicts poor survival from ovarian cancer. The study also identified genes which help the cancer develop resistance to chemotherapy - offering a new route to help tackle the disease.

28 Jun 2016

Scientists find tiny organisms in upper female reproductive tract once thought to be sterile

They're inside our gut, on the skin, and in the mouth. Thousands of different types of micro-organisms live in and on the body, playing helpful roles in digestion or in aiding the body's natural defense system.

6 Jun 2016

New research reveals advances that could change gynecologic cancer standard-of-care treatments

Advances that could change gynecologic cancer standard-of-care treatments are the centerpiece of key studies being presented by researchers from The University of Texas MD Anderson Cancer Center's Department of Gynecologic Oncology and Reproductive Medicine at the 2016 Annual Meeting of the American Society of Clinical Oncology.

6 Jun 2016

UA researcher aims to identify imaging biomarkers for effective screening of ovarian cancer

University of Arizona researcher Jennifer Barton is leading a two-year, $1 million project funded by the National Cancer Institute to identify imaging biomarkers of ovarian cancer, the most deadly gynecological cancer in the United States.

1 Jun 2016

Oregon's new birth control law could improve access to all forms of contraception

Researchers at Oregon Health & Science University, University of Minnesota School of Public Health and George Mason University applaud Oregon's new birth control law which allows women age 18 or older to obtain some methods of hormonal contraception directly from pharmacies, without having to visit a prescribing clinician, yet note how the law could go even further to improve access to all forms of contraception, according to a viewpoint article published in the Journal of the American Medical Association today.

29 Mar 2016

Researchers reveal inherited genetic mutations associated with ovarian cancer risk

Previous research has established a link between genetic mutations in the BRCA1 and BRCA2 genes to an increased risk of developing ovarian, fallopian tube or peritoneal cancer in women.

11 Feb 2016

Children conceived through infertility treatments no more likely to have developmental delays

Children conceived via infertility treatments are no more likely to have a developmental delay than children conceived without such treatments, according to a study by researchers at the National Institutes of Health, the New York State Department of Health and other institutions.

5 Jan 2016