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Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

A Phase III study of Afinitor (everolimus) tablets in patients with non-cancerous kidney tumors, or angiomyolipomas, associated with tuberous sclerosis complex (TSC) met its primary endpoint of best overall angiomyolipoma response rate, which includes reduction in kidney tumor size and absence of new tumors.

26 Sep 2011

Combination of Afinitor, exemestane reduces risk of breast cancer progression in women

A pivotal Phase III study shows Afinitor (everolimus) tablets plus exemestane, a hormonal therapy, more than doubled the time women lived without tumor growth (progression-free survival; PFS) and significantly reduced the risk of cancer progression by 57% versus exemestane alone in patients with advanced breast cancer.

26 Sep 2011

Sodium Stibogluconate & Paromomycin combination treatment for Kala azar

East Africa is fighting the worst kala azar outbreak in a decade. Collaboration across the region through the Leishmaniasis East Africa Platform (LEAP) has resulted in the development of a new combination therapy (SSG&PM) which is cheaper and nearly halves the length of treatment from a 30 day course of injections to 17 days.

26 Sep 2011

Janssen Biotech receives FDA approval for Remicade to treat UC in children

The U.S. Food and Drug Administration today approved Remicade (infliximab) to treat moderately to severely active ulcerative colitis (UC) in children older than 6 years who have had inadequate response to conventional therapy.

26 Sep 2011

E.U. CHMP issues positive opinion for use of Celgene's REVLIMID/dexamethasone MM drug

Celgene International Sàrl was notified today that the E.U. Committee for Medicinal Products for Human Use (CHMP), on behalf of the European Medicines Agency (EMA) has concluded an Article 20 review of REVLIMID and issued a positive opinion for the use of REVLIMID in combination with dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy.

23 Sep 2011

HealthWell Foundation introduces new lupus fund

The HealthWell Foundation, a nonprofit organization providing financial assistance to insured patients facing a variety of chronic and life-altering illnesses, announces the launch of a new fund supporting treatment for Systemic Lupus Erythematosus (SLE), the most common form of lupus.

22 Sep 2011

Test to properly diagnose fever in children needed 'desperately'

"[F]ar too many children in Kenya and other African countries continue to suffer unnecessarily each year due to the misdiagnosis of fever, which contributes to the deaths of nearly three million children of less than five years of age from malaria and pneumonia," Willis Akhwale, head of Kenya's Department of Disease Prevention and Control in the Ministry of Public Health and Sanitation, writes in a Daily Nation opinion piece.

21 Sep 2011

African Americans more likely than Caucasians to develop and die from lung cancer

Lung cancer, the leading cause of cancer death in the U.S., takes a particularly heavy toll on African Americans. Despite their lower smoking rates, African Americans are more likely than Caucasians to develop and die from lung cancer.

21 Sep 2011

Two IGB faculty members recognized as University Scholars

Paul Kenis and James Slauch have been named as University Scholars, a program created to recognize the university's most talented teachers, scholars and researchers.

21 Sep 2011

Yoghurt consumption whilst pregnant linked to asthma and hay fever in offsping

Women who eat low-fat yoghurt while pregnant increase their chances of having children who develop asthma and hay fever, a study has found. Belief till now was completely the opposite.

21 Sep 2011

Bird flu strikes Eastern India yet again as culling operations begin

On Tuesday, the federal government in India announced that it had ordered poultry farms in the eastern part of the country to cull chickens and destroy eggs to rein in an new outbreak of bird flu.

21 Sep 2011

Antivirals from shark cartilage compound squalamine

A unique compound originally isolated from sharks could prove to be a promising treatment for hepatitis B and C and other viral diseases, researchers say. Known as squalamine, the drug has not yet been tested as an antiviral agent in humans, but it has been given to hundreds of people enrolled in clinical trials designed to test its usefulness for other conditions. Researchers say they hope to begin human trials to test the compound’s antiviral activity within the next year.

21 Sep 2011

Pakistan officials move to contain dengue epidemic that has infected thousands

"On top of a raging insurgency and devastating seasonal floods, Pakistan is reeling from a particularly acute outbreak of dengue fever that has left local authorities scrambling to contain the epidemic" and has put a strain on the health care system, the Washington Post reports, adding that the disease "has already infected thousands across the country and killed as many as two dozen people."

21 Sep 2011

Niiki Pharma announces positive data from ongoing trial of novel anti-cancer agent NKP-1339

Niiki Pharma Inc. announced interim results from the ongoing Phase I clinical trial of its lead product, NKP-1339. NKP-1339 is a first-in-class transferrin targeted small molecule that down-regulates GRP78, a key regulator of mis-folded protein processing and a tumor survival factor.

20 Sep 2011

Umeå University´s Centre for Global Health Research hosts meeting on Dengue fever

On September 21-23, researchers and specialists from 11 countries, including Thailand, Singapore, Brazil, Sri Lanka, Malaysia, and several European countries, will meet in Umeå to begin a four-year collaboration set to enable the surveillance and control of Dengue fever.

19 Sep 2011

NanoViricides acquires light industrial building for laboratory facilities and cGMP production

NanoViricides, Inc. announced that Inno-Haven LLC has completed acquisition of a light industrial building. The Company anticipates that it will be leasing a portion of this space, in the near future, for laboratory facilities and cGMP production of its nanoviricides® drug candidates against various viral diseases.

19 Sep 2011

Eating low-fat yoghurt whilst pregnant can increase risk of asthma, hay fever in children

Eating low-fat yoghurt whilst pregnant can increase the risk of your child developing asthma and allergic rhinitis (hay fever), according to recent findings.

19 Sep 2011

Congressional cuts to global health R&D spending would hinder preparations for new pandemic threats

The movie "'Contagion' is fiction, but truth closely trails behind. It tells an effective story of why we need new vaccines, tests, drugs, and other tools to prevent, diagnose, and treat diseases to address existing and emerging global health threats," Kaitlin Christenson, coalition director of the Global Health Technologies Coalition (GHTC), writes in an opinion piece in The Hill's "Congress Blog."

17 Sep 2011

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

Novartis announced today positive results of the first pivotal Phase III trial of ACZ885 in patients with systemic juvenile idiopathic arthritis (SJIA), a rare and serious childhood auto-inflammatory disease. The results, presented at the 2011 European Pediatric Rheumatology Congress in Bruges, Belgium, showed all primary and secondary endpoints of the study were met.

17 Sep 2011

New research aims to control transmission of infectious diseases

New research aimed at controlling the transmission of diseases among humans, other animals and the environment is being made possible by grants from a collaboration among U.S. and U.K. funding agencies.

15 Sep 2011

Fever News and Research

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

Combination of Afinitor, exemestane reduces risk of breast cancer progression in women

Sodium Stibogluconate & Paromomycin combination treatment for Kala azar

Janssen Biotech receives FDA approval for Remicade to treat UC in children

E.U. CHMP issues positive opinion for use of Celgene's REVLIMID/dexamethasone MM drug

HealthWell Foundation introduces new lupus fund

Test to properly diagnose fever in children needed 'desperately'

African Americans more likely than Caucasians to develop and die from lung cancer

Two IGB faculty members recognized as University Scholars

Yoghurt consumption whilst pregnant linked to asthma and hay fever in offsping

Bird flu strikes Eastern India yet again as culling operations begin

Antivirals from shark cartilage compound squalamine

Pakistan officials move to contain dengue epidemic that has infected thousands

Niiki Pharma announces positive data from ongoing trial of novel anti-cancer agent NKP-1339

Umeå University´s Centre for Global Health Research hosts meeting on Dengue fever

NanoViricides acquires light industrial building for laboratory facilities and cGMP production

Eating low-fat yoghurt whilst pregnant can increase risk of asthma, hay fever in children

Congressional cuts to global health R&D spending would hinder preparations for new pandemic threats

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

New research aims to control transmission of infectious diseases

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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