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Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

Novartis announced today positive results of the first pivotal Phase III trial of ACZ885 in patients with systemic juvenile idiopathic arthritis (SJIA), a rare and serious childhood auto-inflammatory disease. The results, presented at the 2011 European Pediatric Rheumatology Congress in Bruges, Belgium, showed all primary and secondary endpoints of the study were met.

17 Sep 2011

New research aims to control transmission of infectious diseases

New research aimed at controlling the transmission of diseases among humans, other animals and the environment is being made possible by grants from a collaboration among U.S. and U.K. funding agencies.

15 Sep 2011

Pakistan's Punjab province reports growing dengue outbreak

"The government in Pakistan's eastern province of Punjab is struggling to control a growing dengue fever epidemic, officials say," and they "have warned that it threatens to affect other parts of the country," BBC News reports.

15 Sep 2011

NEJM publishes data from Vertex INCIVEK Phase 3 study on genotype 1 chronic hepatitis C

Vertex Pharmaceuticals Incorporated today announced that the New England Journal of Medicine (NEJM) published data from a Phase 3 study of INCIVEK (telaprevir) tablets in people with genotype 1 chronic hepatitis C who were new to treatment.

15 Sep 2011

Positive data from Aeterna Zentaris' AEZS-108 Phase 2 study on advanced endometrial cancer

Aeterna Zentaris Inc. earlier today, presented positive final Phase 2 efficacy and safety data for its targeted cytotoxic luteinizing hormone releasing hormone (LHRH) analog, AEZS-108, in advanced endometrial cancer.

14 Sep 2011

Merck issues statement on GARDASIL human papillomavirus vaccine

Merck, known as MSD outside the United States and Canada, issued the following statement on GARDASIL, Merck's vaccine to protect against certain diseases caused by human papillomavirus (HPV) types 6, 11, 16 and 18.

14 Sep 2011

Viewpoints: Medicare bigger problem than social security; N.Y.'s long term care 'bad grade'

Sometimes they challenged Perry from the left (on Social Security and Medicare) and sometimes from the right (on immigration, taxes and mandatory vaccines), but it all came back to the same thing: The frontrunner was befuddled – seemingly stunned that his rivals would question his right to the Republican presidential nomination.

14 Sep 2011

Mosquitoes carrying West Nile virus detected

There is a recent surge in the West Nile-carrying mosquitoes after a relatively dry spell accompanied by warm temperatures last week. The health department monitors about 40 traps across the county two times per week, and last week found four traps in Wheaton alone with infected mosquitoes.

12 Sep 2011

ASTMH annual meeting to explore latest research on infectious diseases

The 60th Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH) -- the largest of its kind in the world -- will bring together in one place global experts who are battling a wide range of bacteria, viruses, parasites and other pathogens that each year kill or sicken hundreds of millions of people.

12 Sep 2011

Febrile seizures in children may be linked to respiratory alkalosis

New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity.

12 Sep 2011

Inhibition of Sab protein protects liver from acetaminophen toxicity

New research from the Keck School of Medicine of the University of Southern California (USC) may help prevent damage to the liver caused by drugs like acetaminophen and other stressors.

8 Sep 2011

First-ever comprehensive study of species origins of nature-derived drugs

In a first-ever comprehensive study of the species origins of nature-derived drugs, it is shown that drug-producing species are concentrated and clustered in a limited number of families, refuting the conventional view that as every nature species produces biologically active molecules, one can find drugs from almost any major block of species groups if one looks for them hard enough.

8 Sep 2011

Tick-borne disease in US blood supply

A tick-borne infection known as Babesiosis, which can cause severe disease and even death, is becoming a growing threat to the U.S. blood supply, government researchers said on Monday.

6 Sep 2011

Youth immunization rates encouraging: CDC report

According to a survey by the Centers for Disease Control and Prevention (CDC) out Monday, more and more American adolescents are receiving recommended vaccines.

6 Sep 2011

NanoViricides selects NV-INF-1 anti-influenza drug for FDA submission

NanoViricides, Inc. announced today that it has selected a clinical candidate, now designated NV-INF-1, for FDA submission in its highly successful FluCide anti-influenza therapeutics program.

6 Sep 2011

Positive topline data from 4SC's resminostat Phase II trial on Hodgkin's Lymphoma

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced positive topline data from its Phase II SAPHIRE trial with resminostat, its oral pan HDAC inhibitor, in patients with relapsed/refractory Hodgkin's Lymphoma.

6 Sep 2011

Three cases of novel influenza A virus now linked to agricultural fair in southwestern Pennsylvania

The Pennsylvania departments of Health and Agriculture today announced three cases of a novel influenza A virus have been identified, and are now linked to an agricultural fair in southwestern Pennsylvania.

6 Sep 2011

September issue of JACR summarizes methods for radiation dose optimization in chest CT scans

An article in the September issue of the Journal of the American College of Radiology summarizes methods for radiation dose optimization in chest computed tomography (CT) scans.

2 Sep 2011

New IDSA/PIDS guidelines can thwart pneumonia in children

Immunizations, including a yearly flu vaccine, are the best way to protect children from life-threatening pneumonia, according to new guidelines from the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America.

2 Sep 2011

Special journal edition chronicles 3-D structures of important antibacterial, bioterrorist targets

The September issue of the online scientific journal Acta Crystallographica: Structural Biology and Crystallization Communications (Acta Cryst F) will consist entirely of work done at the Seattle Structural Genomics Center for Infectious Disease (SSGCID), a consortium of researchers from Seattle BioMed, Emerald BioStructures, the University of Washington and Pacific Northwest National Laboratory.

2 Sep 2011

Fever News and Research

Novartis reports positive results from first pivotal ACZ885 Phase III trial in systemic juvenile idiopathic arthritis

New research aims to control transmission of infectious diseases

Pakistan's Punjab province reports growing dengue outbreak

NEJM publishes data from Vertex INCIVEK Phase 3 study on genotype 1 chronic hepatitis C

Positive data from Aeterna Zentaris' AEZS-108 Phase 2 study on advanced endometrial cancer

Merck issues statement on GARDASIL human papillomavirus vaccine

Viewpoints: Medicare bigger problem than social security; N.Y.'s long term care 'bad grade'

Mosquitoes carrying West Nile virus detected

ASTMH annual meeting to explore latest research on infectious diseases

Febrile seizures in children may be linked to respiratory alkalosis

Inhibition of Sab protein protects liver from acetaminophen toxicity

First-ever comprehensive study of species origins of nature-derived drugs

Tick-borne disease in US blood supply

Youth immunization rates encouraging: CDC report

NanoViricides selects NV-INF-1 anti-influenza drug for FDA submission

Positive topline data from 4SC's resminostat Phase II trial on Hodgkin's Lymphoma

Three cases of novel influenza A virus now linked to agricultural fair in southwestern Pennsylvania

September issue of JACR summarizes methods for radiation dose optimization in chest CT scans

New IDSA/PIDS guidelines can thwart pneumonia in children

Special journal edition chronicles 3-D structures of important antibacterial, bioterrorist targets

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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