Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Researchers investigate SARS-CoV-2 specific inflammatory response

New research can confirm that while some of the response from monocytes to SARS-CoV-2 is generic to virus infection, most of it SARS-CoV-2 specific, especially proinflammatory responses.

7 Jan 2022

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Memory B cells never forget recurrent viral exposures and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is no exception, according to a new medRxiv* preprint study.

5 Jan 2022

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Now in new research, scientists from the University of Leicester have been investigating how these mutations alter the affinities of RBDs to ACE2.

28 Dec 2021

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Infection-fighting B cells retain better memory of the coronavirus spike protein in University Hospital patients who recover from less-severe cases of COVID-19 than in those recovering from severe COVID-19, a new study suggests.

24 Dec 2021

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

A new study shows that although the Omicron variant exhibits significant immune escape compared to other SARS-CoV-2 variants, antibody neutralization can be largely restored with booster doses of mRNA vaccines.

22 Dec 2021

Defensosomes can act as decoys to protect against SARS-CoV-2

In a new study, researchers from New York University have been examining the ability of defensosomes to combat SARS-CoV-2 infection.

22 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Researchers discuss the sensitivity of the SARS-CoV-2 Omicron variant towards various monoclonal antibodies.

20 Dec 2021

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Researchers demonstrated the unexpected roles of nucleocapsid protein in innate and adaptive immunity to SARS-CoV-2.

15 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Novel immunotherapy shows promise for children, young adults with recurrent AML

An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return.

12 Dec 2021

Infant immune system beats the adult immune system at fighting off new pathogens

As any parent knows, infants are prone to getting respiratory infections.

12 Dec 2021

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Researchers from Sorbonne Universite have been investigating the effect of the BNT162b2 mRNA vaccine on HIV-positive individuals.

9 Dec 2021

Exploring SARS-CoV-2 vaccine responsiveness in immunosuppressed patients

A new study indicates an immunological response to SARS-CoV-2 vaccines in immunosuppressed patients that were comparable to healthy patients.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

New marker could lead to better diagnoses of Covid-19

Biomedical scientists at LMU have found a new marker in the blood of Covid-19 patients. It furnishes insights into the course and development of the disease and could lead to better diagnoses.

6 Dec 2021

New approach to COVID-19 immune profiling using blood-based machine learning

A new study discusses the application of a novel deconvolution model AImmune to predict moderate and severe cases of COVID-19.

5 Dec 2021

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Flow Cytometry News and Research

Further Reading

Researchers investigate SARS-CoV-2 specific inflammatory response

After SARS-CoV-2 booster dose memory B cells adapt to Omicron

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Study hints subtle differences in the quality of immune response based on COVID-19 severity

Importance of booster vaccine doses for maintaining protection against the SARS-CoV-2 Omicron variant

Defensosomes can act as decoys to protect against SARS-CoV-2

Molecular mechanism of SARS-Cov-2-induced thrombosis

Reduced antibody-mediated neutralization by the SARS-CoV-2 Omicron variant

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Novel immunotherapy shows promise for children, young adults with recurrent AML

Infant immune system beats the adult immune system at fighting off new pathogens

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Exploring SARS-CoV-2 vaccine responsiveness in immunosuppressed patients

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

New marker could lead to better diagnoses of Covid-19

New approach to COVID-19 immune profiling using blood-based machine learning

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

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Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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