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Lipid-peptide nanocomplexes offer new mRNA platform

A new paper reports the methodical development of lipid-peptide nanocomplexes as a delivery vehicle for messenger ribonucleic acid molecules to the tumor cell, in vitro and in vivo.

27 Jun 2022

Study unveils a precise model for the stinging organelle of starlet sea anemone

Summertime beachgoers are all too familiar with the painful reality of a jellyfish sting. But how do the stinging cells of jellyfish and their coral and sea anemone cousins actually work? New research from the Stowers Institute for Medical Research unveils a precise operational model for the stinging organelle of the starlet sea anemone, Nematostella vectensis.

23 Jun 2022

SARS-CoV-2 evades natural killer cell cytotoxic responses

In a recent study posted to the bioRxiv* preprint server, researchers at Stanford University School of Medicine revealed the mechanism via severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escapes natural killer (NK) cell cytotoxic reactions.

22 Jun 2022

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

In a recent study posted to the bioRxiv* preprint server, researchers at Weill Cornell Medical College assessed the cleavability of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and related coronaviruses by several proteases of the host.

19 Jun 2022

New sensor accurately determines the human saliva pH

Chemists at the Ural Federal University have created a sensor for determining the human saliva pH. This is a fluorophore with strong and stable emission, which picks up the smallest fluctuations in the pH(tenths) in biological fluids.

16 Jun 2022

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

Bruker Corporation today announced the release of the NeuraLight 3D Ultra™ module to support advanced neuroscience and optogenetics research applications on Bruker’s Ultima multiphoton microscopes.

From Bruker Nano Surfaces and Metrology 16 Jun 2022

UIC scientists identify a dynamic duo of cells in lung blood vessels

Scientists at the University of Illinois Chicago have analyzed gene expression data from more than 35,000 blood vessel cells from the lungs of mice and identified two subtypes.

14 Jun 2022

New near-infrared probe may aid in early diagnosis of Alzheimer's disease

Inside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amyloid-beta (Aβ) protein, which is vital for brain growth, can become tainted and destroy cells, which leads to forgetfulness and memory loss.

14 Jun 2022

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States demonstrated that the acidic milieu of the nasal cavity is critical for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tropism.

14 Jun 2022

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

Researchers have successfully treated type 1 diabetes in mice using pancreatic beta-cell, target-specific, chimeric antigen-receptor (CAR) regulatory T cells (Tregs), and demonstrated the feasibility of their approach to treat the human condition according to data being presented Monday, June 13 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

New fluorogenic probe could quickly detect the presence of influenza A virus

The influenza A virus, which is responsible for seasonal flu outbreaks, is also the only influenza virus that has previously caused flu pandemics.

6 Jun 2022

CRISPR-based diagnostics for SARS-CoV-2 detection

In a recent study posted to the Journal of Biochemical and Molecular Toxicology, researchers reviewed clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jun 2022

Scientists develop new technology to solve common surgical problem of nerve damage

A research collaboration including scientists from Oregon State University has developed a new technology to help surgeons know where a patient's nerves are, lessening the chance of nerve damage.

1 Jun 2022

Novel photonic technology could enable fluorescent sensors to track molecules deep inside the body

Fluorescent sensors, which can be used to label and image a wide variety of molecules, offer a unique glimpse inside living cells.

30 May 2022

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Researchers compared the polymer-nanoparticle hydrogel system and standard routes of delivery of broadly neutralizing antibodies against SARS-CoV-2 in a mouse model.

27 May 2022

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Researchers differentiated between SARS-CoV-2 variants using nanotechnology.

26 May 2022

Mucosal COVID vaccine candidate powerfully protective in macaques

A recent research paper posted to the bioRxiv* preprint server illustrated the protective efficacy of the intranasal pediatric parainfluenza virus-vectored coronavirus disease 2019 (COVID-19) vaccine prospect, B/HPIV3/S-6P, in macaques.

26 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Researcher from The University of Colorado Anschutz Medical Campus to receive DeNovix Platinum Edition CellDrop

DeNovix Inc. is pleased to announce the winner of the Platinum Edition CellDrop Giveaway: Dr. Christina Roark from The University of Colorado Anschutz Medical Campus, USA! Selected at random from thousands of entries from scientists worldwide, the CellDrop will be housed in Dr. Roark’s lab in the Allergy and Clinical Immunology Division in the Department of Medicine.

From DeNovix Inc. 24 May 2022

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.

24 May 2022

Fluorescence News and Research

Lipid-peptide nanocomplexes offer new mRNA platform

Study unveils a precise model for the stinging organelle of starlet sea anemone

SARS-CoV-2 evades natural killer cell cytotoxic responses

SARS-CoV-2 variants of concern exhibit divergent interactions with host proteases

New sensor accurately determines the human saliva pH

Bruker introduces enhanced 3D holographic stimulation for optogenetics on its Ultima 2Pplus multiphoton microscope

UIC scientists identify a dynamic duo of cells in lung blood vessels

New near-infrared probe may aid in early diagnosis of Alzheimer's disease

Molecular snapshots of the productive infectious entry pathway of SARS-CoV-2 into cells

Researchers demonstrate the feasibility of pancreatic beta-cell, target-specific CAR-Treg treatment for T1D

New fluorogenic probe could quickly detect the presence of influenza A virus

CRISPR-based diagnostics for SARS-CoV-2 detection

Scientists develop new technology to solve common surgical problem of nerve damage

Novel photonic technology could enable fluorescent sensors to track molecules deep inside the body

A polymer-nanoparticle hydrogel to subcutaneously deliver broadly neutralizing antibodies against SARS-CoV-2

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Mucosal COVID vaccine candidate powerfully protective in macaques

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Researcher from The University of Colorado Anschutz Medical Campus to receive DeNovix Platinum Edition CellDrop

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

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Expanding research and clinical options for children with cancer

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