Gastroesophageal Reflux Disease News and Research

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Gastroesophageal reflux disease (GERD) is a more serious form of gastroesophageal reflux (GER), which is common. GER occurs when the lower esophageal sphincter (LES) opens spontaneously, for varying periods of time, or does not close properly and stomach contents rise up into the esophagus. GER is also called acid reflux or acid regurgitation, because digestive juices—called acids—rise up with the food. The esophagus is the tube that carries food from the mouth to the stomach. The LES is a ring of muscle at the bottom of the esophagus that acts like a valve between the esophagus and stomach.

Index endoscopy results are crucial for assessment of Barrett's patients

A new study indicates that both high-grade abnormal cellular changes (dysplasia) and esophageal adenocarcinoma (a form of cancer) have increased in the last 25 years among people with a digestive condition known as Barrett's esophagus.

15 Feb 2019

MUSC researchers uncover a new cause for laryngeal symptoms

While a sudden coughing fit is a protective reflex to clear the airway, chronic cough can be caused by multiple factors that must be investigated to determine treatment. Cough is just one of several laryngeal symptoms including hoarseness and dysphoric breathing that can become debilitating.

4 Jan 2019

Change in genome of Caucasians could explain higher rates of esophageal cancer

A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds.

21 Dec 2018

Determining acid-neutralizing capacity for OTC antacids

USP<301> describes a back-titration to determine the acid-neutralizing capacity (ANC).

From Metrohm USA Inc. 17 Oct 2018

NYU Langone Hospital–Brooklyn offers advanced robot-assisted surgery to treat complex hernias

Most people refrain from calling attention to the unusual bulge in their lower abdomen. But it could be a potentially dangerous condition that needs to be discussed with your doctor right away.

28 Aug 2018

Researchers find distinct microbiomes in airway, gastrointestinal systems of children with chronic cough

Different respiratory diseases associated with chronic cough create distinct microbial imbalances in the lower airways of children, according to a study led by researchers at NYU School of Medicine.

26 Jul 2018

PENTAX Medical launches new C2 CryoBalloon Ablation System for treatment of Barretts esophagus

PENTAX Medical Company, a healthcare industry leader in diagnostic and therapeutic endoscopy, announces the introduction of the C2 CryoBalloon Ablation System for the treatment of Barrett’s esophagus, a condition in which the lining of the esophagus develops abnormal lesions primarily as a result of chronic gastroesophageal reflux disease.

From PENTAX Medical Company 8 Jun 2018

Esophageal cancer risk could be reduced by esomeprazole and low dose aspirin

According to the results of a phase III trial presented at the 2018 ASCO Annual Meeting, two simple over-the-counter medicines – high dose esomeprazole and low dose aspirin when taken regularly can moderately lessen the risk of high grade esophageal cancer in patients who are diagnosed with Barrett’s esophagus when taken for at least 7 years.

5 Jun 2018

Invasive surgery should be done for select patients with acid reflux, says study

As the number of Americans with acid reflux grows, a study by researchers at the University of Colorado Anschutz Medical Campus says invasive procedures to treat those who don't respond to medication should be done for select patients.

8 May 2018

New guideline on use of endoscopic eradication therapy in Barrett's esophagus

The latest issue of GIE: Gastrointestinal Endoscopy, the official journal of the American Society for Gastrointestinal Endoscopy, includes a new society guideline on use of endoscopic eradication therapy Barrett's esophagus.

6 Apr 2018

$Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients$

Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients

Long-term proton pump inhibitor (PPI) use does not increase the risk of hip fracture among persons with Alzheimer's disease, according to a new study from the University of Eastern Finland.

13 Mar 2018

Acid reflux linked to cancer of respiratory and upper digestive tracts in older adults

Acid reflux was associated with cancer of the respiratory and upper digestive tracts in older adults.

21 Dec 2017

PPI use not linked to increased risk of developing dementia

Proton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD).

21 Nov 2017

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S.

11 Oct 2017

Common acid reflux drugs linked to progression of chronic liver disease

Approximately 10 percent of the general population take a proton pump inhibitor (PPI) drug to block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux and gastroesophageal reflux disease.

10 Oct 2017

New studies provide insight into treatments for Barrett's esophagus

The October issue of GIE: Gastrointestinal Endoscopy features several new studies evaluating various treatments for Barrett's esophagus (BE). Two of these studies are highlighted below. BE is a condition in which there are unusual changes to the cells lining the esophagus. It is believed to be most commonly due to inflammation from gastroesophageal reflux disease (GERD).

6 Oct 2017

Study finds no convincing evidence to support link between PPI use and dementia risk

Several studies have reported associations between proton-pump inhibitor (PPI) use and dementia. New research published on July 18 in Gastroenterology, the official journal of the American Gastroenterological Association, puts these claims to rest.

20 Jul 2017

Longtime use of heartburn drugs linked to increased risk of death

Popular heartburn drugs called proton pump inhibitors (PPIs) have been linked to a variety of health problems, including serious kidney damage, bone fractures and dementia.

4 Jul 2017

Researchers identify mechanisms involved in acid pump

Researchers at Aarhus University, Denmark, have succeeded in identifying the mechanisms involved in what is known as the acid pump, which at the cellular level pumps acid into the stomach - in some cases leading to gastric ulcers and gastroesophageal reflux disease.

7 Mar 2017

AGA creates Obesity Practice Guide for effective weight management in obese patients

Patients with obesity need a multidisciplinary approach to achieve a healthy weight, and the American Gastroenterological Association (AGA) believes that gastroenterologists are in a unique position to lead the care team.

28 Feb 2017