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Epigenetic changes from stress exposure can be passed from traumatized parent to offspring

The children of traumatized people have long been known to be at increased risk for posttraumatic stress disorder (PTSD), and mood and anxiety disorders.

1 Sep 2016

New research sheds light on underlying genetic basis of heart arrhythmias

In the August 31 issue of Science Translational Medicine, new research from the University of Chicago shows how deficits in a specific pathway of genes can lead to the development of atrial fibrillation, a common irregular heartbeat, which poses a significant health risk.

31 Aug 2016

UTHealth scientists discover powerful predictors of congestive heart failure

A team of scientists at The University of Texas Health Science Center at Houston and Baylor College of Medicine, led by Eric Boerwinkle, Ph.D., Richard Gibbs, Ph.D., and Bing Yu, Ph.D., have identified powerful predictors of congestive heart failure, a major cause of hospitalization and death in the United States.

31 Aug 2016

Researchers identify new gene for type 2 diabetes at well-established genomic location

Gene researchers have used sophisticated scientific tools to reveal a new gene for type 2 diabetes at a well-established genomic location.

31 Aug 2016

Research findings could lead to new biomarker for early stages of tumor development

To treat or not to treat? That is the question researchers at the Department of Energy's Lawrence Berkeley National Laboratory hope to answer with a new advance that could help doctors and their cancer patients decide if a particular therapy would be worth pursuing.

31 Aug 2016

MRSA correlated to eczema? An interview with Dr Bjorn Herpers

There is a lot of evidence that Staphylococcus aureus (S. aureus) is involved in eczema. Eczema is now thought to be caused by a barrier dysfunction of the skin that allows external triggers to cause an overshoot of inflammation.

31 Aug 2016

Scientists find way to use CRISPR/Cas9 technology to diagnose and inactivate cancer mutations

As for many other biomedical and biotechnology disciplines, the genome scissor "CRISPR/Cas9" also opens up completely new possibilities for cancer research.

31 Aug 2016

New study shows variation in junk DNA can affect health

All humans are 99.9 percent identical, genetically speaking. But that tiny 0.1 percent variation has big consequences, influencing the color of your eyes, the span of your hips, your risk of getting sick and in some ways even your earning potential.

30 Aug 2016

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool.

30 Aug 2016

Researchers find better way to purify liver cells made from induced pluripotent stem cells

A research team including developmental biologist Stephen A. Duncan, D. Phil., SmartState Chair of Regenerative Medicine at the Medical University of South Carolina, has found a better way to purify liver cells made from induced pluripotent stem cells (iPSCs).

30 Aug 2016

Studying mutant peptides may help detect weaknesses in tumor cells

Researchers from MIPT, the Institute of Biomedical Chemistry, the Institute for Energy Problems of Chemical Physics, and the Research Institute of Physico-Chemical Medicine have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing.

29 Aug 2016

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Although the current practice of analysing defined gene panels for a specific disease has great utility, it is of limited benefit when a condition is not well defined.

29 Aug 2016

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH.

29 Aug 2016

NEJM publishes MINDACT trial results

Agendia, Inc., a world leader in personalized medicine and molecular cancer diagnostics, announces the peer-reviewed publication of the primary outcome results of the Microarray In Node-negative and 1 to 3 positive lymph node Disease may Avoid ChemoTherapy (MINDACT) clinical trial in the prestigious New England Journal of Medicine (NEJM). (i, iii, iv) The publication demonstrates that 46% of breast cancer patients considered for chemotherapy, whose tumors are classified MammaPrint Low Risk, have excellent survival without chemotherapy, and can thus be candidates to avoid this toxic therapy.

29 Aug 2016

Skin cells derived from autistic donors grow faster than those from control subjects

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, chair of the department of genetics and genome sciences at Case Western Reserve University School of Medicine.

28 Aug 2016

Genome News and Research

Epigenetic changes from stress exposure can be passed from traumatized parent to offspring

New research sheds light on underlying genetic basis of heart arrhythmias

UTHealth scientists discover powerful predictors of congestive heart failure

Researchers identify new gene for type 2 diabetes at well-established genomic location

Research findings could lead to new biomarker for early stages of tumor development

MRSA correlated to eczema? An interview with Dr Bjorn Herpers

Scientists find way to use CRISPR/Cas9 technology to diagnose and inactivate cancer mutations

New study shows variation in junk DNA can affect health

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Researchers find better way to purify liver cells made from induced pluripotent stem cells

Studying mutant peptides may help detect weaknesses in tumor cells

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Leading Chikungunya vaccine in clinical trial phase 2

NEJM publishes MINDACT trial results

Skin cells derived from autistic donors grow faster than those from control subjects

Kobe University researchers develop new technique for high-level genome editing operation

Chromatrap develops new range of optimised ChIP assay kits for genetic research

Scientists isolate new multicomponent virus from mosquitoes

Gene fusions in esophageal adenocarcinomas offer new molecular insights into lethal cancer

New study looks to saliva of humans and primates to gain insights into evolution

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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