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Researchers identify molecular patterns that dominate gene expression in the human brain

The human brain may be the most complex piece of organized matter in the known universe, but Allen Institute researchers have begun to unravel the genetic code underlying its function. Research published this month in Nature Neuroscience identified a surprisingly small set of molecular patterns that dominate gene expression in the human brain and appear to be common to all individuals, providing key insights into the core of the genetic code that makes our brains distinctly human.

17 Nov 2015

Improved gene therapy treatment shows promise in mice with cystic fibrosis

An improved gene therapy treatment can cure mice with cystic fibrosis (CF). Cell cultures from CF patients, too, respond well to the treatment. Those are the encouraging results of a study presented by the Laboratory for Molecular Virology and Gene Therapy at KU Leuven, Belgium.

17 Nov 2015

MedUni Vienna researchers discover genetic cause of a rare disease

Researchers at MedUni Vienna have discovered the genetic cause of a rare disease characterized by life-threatening "liver crises" in early childhood and subsequent manifestation of neurological symptoms, such as neuropathy and ataxia (a movement disorder), when they reach school age.

15 Nov 2015

UCSF-led researchers map out melanoma's genetic trajectories

An international team of scientists led by UC San Francisco researchers has mapped out the genetic trajectories taken by melanoma as it evolves from early skin lesions, known as precursors, to malignant skin cancer, which can be lethal when it invades other tissues in the body.

12 Nov 2015

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight. A recent NIH study, for example, found that adults who are obese or overweight at midlife may be at risk for earlier onset of Alzheimer's disease.

12 Nov 2015

March of Dimes scientists help fine-tune experiments to uncover unknown causes of preterm birth

A new, integrated online database of genes and other information related to pregnancy has been developed by March of Dimes Prematurity Research Center investigators to help fine-tune questions, theories, and experiments to uncover the unknown causes of preterm birth.

12 Nov 2015

Crucial change in single DNA base predisposes children to aggressive form of cancer

Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form.

12 Nov 2015

Study shows rare HER2 missense mutations do not spread breast cancer on their own

Results of a new laboratory study by Johns Hopkins Kimmel Cancer Center researchers suggests that some rare “missense” mutations in the HER2 gene are apparently not — on their own — capable of causing breast cancer growth or spread.

12 Nov 2015

Boston Children's Hospital selects Vijay G. Sankaran to receive Rising Star Award

Saluting his spectacular track record to date of innovative research on red blood cell disorders and his future promise as a physician/scientist, Boston Children's Hospital has selected Vijay G. Sankaran, MD, PhD, of Dana-Farber/Boston Children's Cancer and Blood Disorders Center to receive the Rising Star Award at the hospital's third annual Global Pediatric Innovation Summit, Taking on Tomorrow (#PedInno15).

11 Nov 2015

Research opens door for developing biomarker tests to detect cancers early

Biomarkers, which allow diseases to be diagnosed and staged based on relatively non-invasive blood tests, have been identified for several types of cancers, but for most cancers remain elusive. Now, research conducted at the RIKEN Center for Life Science Technologies in Japan and the Harry Perkins Institute of Medical Research in Australia has identified a large number of genes that are upregulated in many different types of cancer, opening the door for developing biomarker tests that could be used to detect cancers early, allowing for prompt treatment.

10 Nov 2015

Deep, uniform exome coverage in one day

Integrated DNA Technologies (IDT), introduces its new xGen® Exome Research Panel v1.0 for insightful analysis of the human exome via next generation sequencing.

From Integrated DNA Technologies 10 Nov 2015

Meat-rich diet may increase kidney cancer risk

A new study indicates that a meat-rich diet may increase the risk of developing kidney cancer through mechanisms related to particular cooking compounds. Also, these associations may be modified by genetic susceptibility to kidney cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study illustrates how diet and genetics may interact to impact cancer risk.

10 Nov 2015

UT Southwestern's Helen H. Hobbs named recipient of Breakthrough Prize in Life Sciences

UT Southwestern Medical Center geneticist Dr. Helen H. Hobbs is the 2016 recipient of the prestigious Breakthrough Prize in Life Sciences.

10 Nov 2015

First comprehensive genomic and biologic study of top skin disease-causing microbes

An international team of scientists, led by researchers from A*STAR's Genome Institute of Singapore (GIS), Institute of Medical Biology (IMB), and Bioinformatics Institute (BII), and P&G, have completed the first comprehensive genomic and biologic study of all species of Malassezia, one of the top skin disease-causing microbes.

9 Nov 2015

Utah chemists devise new way to detect DNA damage

University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.

6 Nov 2015

Researchers identify seven genetic risk loci involved in atopic march

There's a typical "career" for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, working with colleagues from several institutions, has now identified seven genetic risk loci for this course of disease.

6 Nov 2015

UM SOM Dean E. Albert Reece to be honored with 2015 David E. Rogers Award

The Association of American Medical Colleges announced today that University of Maryland School of Medicine Dean E. Albert Reece, MD, PhD, MBA, will receive the 2015 David E. Rogers Award, which honors a medical school faculty member who has made major contributions to improving the health and health care of the American people. He will be presented the Award on November 8, 2015 at the AAMC's Annual Awards Event.

6 Nov 2015

Better understanding of hibernation could help researchers develop treatments for cardiac disease

Wintry weather means hats and scarves for some mammals, and hibernation for others. Hibernation dramatically lowers body temperatures, heart rates and oxygen consumption -- things that would be fatal to other animals. A team reports in ACS' Journal of Proteome Research a study of the proteins and genes that allow squirrels' hearts to stay healthy during the winter.

5 Nov 2015

Researchers find new way to prevent inflammation, accelerate the skin's healing process

Most products on the market today that are used to treat skin problems target the effects of the disease or wound such as inflammation, which can prolong the healing process and result in scarring. However, LSU Assistant Professor Wei Xu and collaborators at Northwestern University discovered a new way to prevent inflammation and to speed up the skin's healing process.

5 Nov 2015

Researchers track re-emergence of scarlet fever-causing bacteria

An international study led by University of Queensland researchers has tracked the re-emergence of a childhood disease which had largely disappeared over the past 100 years.

4 Nov 2015

Genome News and Research

Researchers identify molecular patterns that dominate gene expression in the human brain

Improved gene therapy treatment shows promise in mice with cystic fibrosis

MedUni Vienna researchers discover genetic cause of a rare disease

UCSF-led researchers map out melanoma's genetic trajectories

Berkeley Lab scientists identify genetic factors that influence neurological disorders and body weight

March of Dimes scientists help fine-tune experiments to uncover unknown causes of preterm birth

Crucial change in single DNA base predisposes children to aggressive form of cancer

Study shows rare HER2 missense mutations do not spread breast cancer on their own

Boston Children's Hospital selects Vijay G. Sankaran to receive Rising Star Award

Research opens door for developing biomarker tests to detect cancers early

Deep, uniform exome coverage in one day

Meat-rich diet may increase kidney cancer risk

UT Southwestern's Helen H. Hobbs named recipient of Breakthrough Prize in Life Sciences

First comprehensive genomic and biologic study of top skin disease-causing microbes

Utah chemists devise new way to detect DNA damage

Researchers identify seven genetic risk loci involved in atopic march

UM SOM Dean E. Albert Reece to be honored with 2015 David E. Rogers Award

Better understanding of hibernation could help researchers develop treatments for cardiac disease

Researchers find new way to prevent inflammation, accelerate the skin's healing process

Researchers track re-emergence of scarlet fever-causing bacteria

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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