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Replication timing assays may allow much earlier cancer detection

Scientists have discovered a DNA sequence that is involved in controlling the timing of DNA replication. Because alterations in DNA replication timing are associated with cancer, this discovery may lead to improved methods for cancer detection.

26 Sep 2004

Allow genomic information to be freely available on the internet

This week’s lead editorial in THE LANCET discusses the benefits and potential risks of allowing genomic information to be freely available on the internet

23 Sep 2004

Research may lead to alternatives to antibiotic drugs for treating bacterial diseases

UCLA microbiologists report the discovery of a new class of genetic elements, similar to retroviruses, that operate in bacteria, allowing them to diversify their proteins to bind to a large variety of receptors.

23 Sep 2004

Potential new way to control drug-resistant bacteria

The researchers, who encountered this genetic property while working on an unrelated project, believe that this discovery could lead to the use of genetically engineered phages to treat bacterial infections that have become resistant to antibiotics.

23 Sep 2004

Scientists decipher genetic code of ancient pathogen that causes the horse disease

More than 2,400 years after Hippocrates, the Greek physician born in 460 BC first described the symptoms of glanders, scientists have deciphered the genetic code of the ancient pathogen that causes the horse disease: Burkholderia mallei.

20 Sep 2004

Genome researchers to look at 1918 Spanish flu

University of Washington researchers will be taking part in a multi-site project examining a portion of the genome of the strain of influenza responsible for the "Spanish Flu" outbreak in 1918.

20 Sep 2004

New insights into ancient mating and migration patterns in humans

Men have been tomcatting around since time immemorial, and some traveled far from home to do it, new research suggests.

20 Sep 2004

Newly completed Chromosome 5 sequence will be a powerful tool for scientists trying to understand human disease

Four years after publicly revealing the official draft human genetic sequence, researchers have reached the halfway point in dotting the i's and crossing the t's of the genetic sentences describing how to build a human.

16 Sep 2004

Suprising new information on the HOX genes

Researchers at the University of Bergen are now able to present new information on the HOX genes – the “software” to design animals. The findings are published in today’s issue of Nature.

10 Sep 2004

New view of chromatin and gene activity

A genome - the DNA instructions for an organism - does not act alone. DNA is packaged with proteins into 'chromatin', which may be more or less tightly condensed. A popular proposal is that active genes are in 'open' chromatin (to allow access to them) and inactive genes are in tightly packed 'compact' chromatin.

10 Sep 2004

Missing genes may help explain why plague bacteria are so deadly

What makes the germ that causes plague so fearsomely lethal, while a close relative only produces digestive disorders and is rarely fatal?

10 Sep 2004

Studies of human genetic variation have found strong evidence for the action of natural selection

One of the most comprehensive studies of the forces that have shaped patterns of human genetic variation has found strong evidence for the action of natural selection, which may help explain why certain people are at risk for a variety of conditions and others are not.

8 Sep 2004

Genomic researchers and Canadian cancer treatment specialists meet in Halifax in order to improve cancer treatment outcomes

The Canadian Association of Radiation Oncologists and leading genomic cancer researchers will meet, Thursday, September 9 to 12th, 2004 at the Westin Nova Scotian Hotel in Halifax, to present research studies' results and to confer on methods to zero in on how to begin to utilize genomics, proteomics, and radiation, to improve cancer treatment outcomes for patients.

8 Sep 2004

Researchers uncover how HIV causes abnormalities in antibody-producing cells

HIV wreaks much of its damage by targeting the “orchestra conductor” of the immune system, a key class of T cells—CD4+ T cells—whose destructive relationship with HIV has been well-studied by AIDS researchers.

8 Sep 2004

Japanese research lab to use an IBM supercomputer for protein research

IBM announced today that AIST, a leading Japanese research laboratory, will use an IBM BlueGene/L supercomputer to advance their research in proteins, potentially accelerating breakthroughs in drug design. The BlueGene/L supercomputer has been ranked as the fourth largest supercomputer in the world.

8 Sep 2004