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QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

Queen Mary University of London and Barts Health NHS Trust have received £10.2m from Barts Charity for the creation of a world-class cardiovascular academic medical centre at the Trust's Barts Heart Centre, St Bartholomew's Hospital.

22 Dec 2015

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

Immune suppressor cells called MDSCs (myeloid-derived suppressor cells) may be important in developing treatments for advanced prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center.

22 Dec 2015

Scientists identify 52 genetic variations associated with age-related macular degeneration

In one of the latest examples of precision medicine, teams of geneticists from nine countries, involving more than 100 scientists, analyzed the genes of more than 33,000 individuals in the hope of finding genetic variations responsible for age-related macular degeneration (AMD), the leading cause of vision loss among people age 50 or older.

22 Dec 2015

Scientists identify genes linked to human intelligence

Scientists from Imperial College London have identified for the first time two clusters of genes linked to human intelligence.

22 Dec 2015

Mirati announces initiation of glesatinib Phase 2 clinical trial in NSCLC patients

Mirati Therapeutics, Inc. today announced that the Phase 2 clinical trial of glesatinib (MGCD265) has commenced. The Company also announced that "glesatinib" is the proposed generic name for MGCD265.

21 Dec 2015

Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

Luminex Corporation today announced that it has received FDA clearance for its NxTAG Respiratory Pathogen Panel that detects 20 clinically relevant viral and bacterial respiratory pathogens, including the atypical bacteria Chlamydophila pneumoniae and Mycoplasma pneumonia.

20 Dec 2015

Research opens door to validation studies in multiple tumor types of liquid biopsy

Pancreatic cancer tumors spill their molecular secrets into the blood stream, shedding their complete DNA and RNA wrapped inside protective lipid particles that make them ripe for analysis with a liquid biopsy, researchers at The University of Texas MD Anderson Cancer Center report online at the Annals of Oncology.

18 Dec 2015

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

Embryos require adequate amounts of energy so that they can successfully progress through each of their cell divisions.

16 Dec 2015

Discovery could pave way for targeted therapies to treat penile cancer

Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.

15 Dec 2015

New study describes a way to identify complex type of mutation in cancer genomes

New research shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients' tumors. Further, a significant percentage of these complex mutations are found in well-known cancer genes that could be targeted by existing drugs, potentially expanding the number of cancer patients who may benefit.

15 Dec 2015

WaferGen Bio-systems signs collaboration agreement with Luxembourg Institute of Health

WaferGen Bio-systems announced today that the Company has signed a collaboration agreement with the Luxembourg Institute of Health, a leading public medical research center that specializes in oncology, infectious diseases, immunology, and population health.

15 Dec 2015

Researchers trace origins of early abnormal brain overgrowth in ASD

Further underscoring the prenatal origins of Autism Spectrum Disorder (ASD), researchers at University of California, San Diego School of Medicine describe for the first time how abnormal gene activity in cell cycle networks that are known to control brain cell production may underlie abnormal early brain growth in the disorder.

14 Dec 2015

ICGC article lays foundation for the coming era of cancer genomic research

An eye-opening article from the International Cancer Genome Consortium was published today in the prestigious journal Nature Communications. It lays a foundation for the coming era of research in cancer genomics.

13 Dec 2015

Whitehead researchers create 3D map to predict how genes are regulated in normal cells

Whitehead Institute researchers have created a map of the DNA loops that comprise the three dimensional (3D) structure of the human genome and regulate gene expression in human embryonic stem (ES) cells and adult cells. The location of genes and regulatory elements within this chromosomal framework could help scientists better navigate their genomic research, establishing relationships between mutations and disease development.

13 Dec 2015

ASU-led researchers add new worldwide resource to explore genes' deep and hidden messages

After a decade-long $3 billion international effort, scientists heralded the 2001 completion of the human genome as a moon landing achievement for biology and the key to finally solving intractable diseases like cancer.

12 Dec 2015

IBD Plexus brings patients, researchers and doctors together to create IBD research initiative

For the first time, more than 40,000 IBD patients, researchers, and healthcare providers will be brought together by IBD Plexus to create the world's largest registry of IBD patients of all ages which will transform how IBD research is being conducted.

12 Dec 2015

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Oncologists are increasingly using information obtained from investigations of the tumor genome in order to find individualized therapies for patients. They specifically search the hereditary information of cancer cells for mutations that drive malignant growth. By now, targeted drugs against many of these cancer-typical cellular alterations have become available.

11 Dec 2015

Probe based qPCR assay complete solution

Integrated DNA Technologies (IDT) has introduced its latest addition to an expanding genomic applications portfolio: PrimeTime® Gene Expression Master Mix, an optimized enzyme mix for probe-based qPCR

From Integrated DNA Technologies 10 Dec 2015

Lilly, Merck announce another immuno-oncology collaboration

Eli Lilly and Company and Merck, known as MSD outside the United States and Canada, today announced another immuno-oncology collaboration that will evaluate abemaciclib (LY2835219), Lilly's cyclin-dependent kinase (CDK) 4 and 6 inhibitor, and Merck's KEYTRUDA (pembrolizumab) in a Phase I study across multiple tumor types.

10 Dec 2015

Study reveals molecular function of protein essential for replication of H5N1 flu virus

An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza virus.

10 Dec 2015

Genomic News and Research

QMUL, Barts Health NHS Trust receive £10.2m to create new cardiovascular academic medical centre

MD Anderson study reveals MDSCs as likely target for developing prostate cancer treatments

Scientists identify 52 genetic variations associated with age-related macular degeneration

Scientists identify genes linked to human intelligence

Mirati announces initiation of glesatinib Phase 2 clinical trial in NSCLC patients

Luminex's NxTAG Respiratory Pathogen Panel obtains FDA clearance

Research opens door to validation studies in multiple tumor types of liquid biopsy

Mitochondrial variation and viable pregnancy: an interview with Dr Elpida Fragouli

Discovery could pave way for targeted therapies to treat penile cancer

New study describes a way to identify complex type of mutation in cancer genomes

WaferGen Bio-systems signs collaboration agreement with Luxembourg Institute of Health

Researchers trace origins of early abnormal brain overgrowth in ASD

ICGC article lays foundation for the coming era of cancer genomic research

Whitehead researchers create 3D map to predict how genes are regulated in normal cells

ASU-led researchers add new worldwide resource to explore genes' deep and hidden messages

IBD Plexus brings patients, researchers and doctors together to create IBD research initiative

Researchers find new method to create uniform standards in search for cancer-relevant mutations

Probe based qPCR assay complete solution

Lilly, Merck announce another immuno-oncology collaboration

Study reveals molecular function of protein essential for replication of H5N1 flu virus

Genetics & Genomics - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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