Genomic News and Research

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Migration of antibiotic resistance from animal feeding operations into groundwater

The routine use of antibiotics in swine production can have unintended consequences, with antibiotic resistance genes sometimes leaking from waste lagoons into groundwater.

22 Aug 2007

Genomic factors may play a role in alcohol and tobacco use

Alcohol and smoking can be harmful, if not deadly. While the desire for these substances can be due to environmental cues, genomic factors also play an important role.

13 Aug 2007

Colon cancer may benefit from hormone replacement therapy

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have found new evidence suggesting that colon cancer is actually a disease of missing hormones that could potentially be treated by hormone replacement therapy.

2 Aug 2007

New risk genes for multiple sclerosis

Two new large-scale genomic studies have honed in on the main genetic pathway associated with multiple sclerosis (MS), while also uncovering new genetic variations in the disease and suggesting a possible link between MS and other autoimmune diseases.

1 Aug 2007

Genomics study provides insight into the evolution of unique human traits

Researchers from the University of Colorado Health Sciences Center, along with colleagues from Stanford University, report the results of a large-scale, genome-wide study to investigate gene copy number differences among ten primate species, including humans.

1 Aug 2007

Researchers track how a single molecule of RNA or DNA unwinds

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters.

27 Jul 2007

Gene expression pattern could lead to improved treatment of pediatric septic shock

A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock , still a serious public health problem despite today's potent antibiotics and pediatric intensive care units.

27 Jul 2007

New algorithm matches any tumor cells to best possible anti-cancer treatments

Cancer patients don't have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.

24 Jul 2007

Effects of aging hematopoietic stem cells

There is little disagreement that the body's maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why.

24 Jul 2007

Simple method to comb genomes

Instead of immutable proprietary software, any species, genetic information resembles open source code that is constantly tweaked and optimized to meet the users specific needs.

20 Jul 2007

Sequential and combination chemotherapy equally effective in treating advanced colorectal cancer

Many patients with incurable advanced colorectal cancer could be offered a more gentle treatment strategy starting with a single chemotherapy drug, as an alternative to current standard initial combination chemotherapy, without compromising their survival.

16 Jul 2007

Discovery of one important function of junk DNA

Scientists have only recently begun to speculate that what's referred to as junk DNA , the 96 percent of the human genome that doesn't encode for proteins and previously seemed to have no useful purpose , is present in the genome for an important reason.

13 Jul 2007

Scientists develop largest ever series of human breasts cancers grafted into mice

At the Institut Curie, Inserm researchers and physicians have established the largest ever panel of human breast cancer xenografts in animal models.

13 Jul 2007

Sigma-Aldrich launches Imprint DNA Modification kit

Sigma-Aldrich has announced the launch of the Imprint DNA Modification kit.

11 Jul 2007

Discovery of enzyme critical in DNA replication

In this week's issue of Science, researchers from the National Institute of Environmental Health Sciences (NIEHS) and Umea University in Sweden report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays in replicating DNA in higher organisms such as yeast and perhaps even humans.

9 Jul 2007

RNA molecules can orchestrate gene activity across vast portions of the human genome

Large, seemingly useless pieces of RNA - a molecule originally considered only a lowly messenger for DNA - play an important role in letting cells know where they are in the body and what they are supposed to become, researchers at Stanford University School of Medicine have discovered.

29 Jun 2007

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

Most known human genes in the genome map are still incompletely annotated, says Professor Alexandre Reymond, from the Centre for Integrative Genomics, University of Lausanne, Switzerland and the Department of Genetic Medicine, University of Geneva, Geneva, Switzerland.

19 Jun 2007

True nature of heterochromatin revealed

Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.

19 Jun 2007

Researchers use 'genomic pathway' to predict Parkinson's

A new Mayo Clinic study provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway largely explain why some persons get Parkinson's disease while others don't, and even predict with great accuracy at what age people might develop their first symptoms.

17 Jun 2007

Discovery of IKBKE gene linked to breast cancer

Using a novel three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers.

17 Jun 2007

Genomic News and Research

Migration of antibiotic resistance from animal feeding operations into groundwater

Genomic factors may play a role in alcohol and tobacco use

Colon cancer may benefit from hormone replacement therapy

New risk genes for multiple sclerosis

Genomics study provides insight into the evolution of unique human traits

Researchers track how a single molecule of RNA or DNA unwinds

Gene expression pattern could lead to improved treatment of pediatric septic shock

New algorithm matches any tumor cells to best possible anti-cancer treatments

Effects of aging hematopoietic stem cells

Simple method to comb genomes

Sequential and combination chemotherapy equally effective in treating advanced colorectal cancer

Discovery of one important function of junk DNA

Scientists develop largest ever series of human breasts cancers grafted into mice

Sigma-Aldrich launches Imprint DNA Modification kit

Discovery of enzyme critical in DNA replication

RNA molecules can orchestrate gene activity across vast portions of the human genome

Many of the areas of the human genome previously thought to be deserts are in fact teeming with life

True nature of heterochromatin revealed

Researchers use 'genomic pathway' to predict Parkinson's

Discovery of IKBKE gene linked to breast cancer

Genetics & Genomics - Second Edition eBook

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Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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