Glucocorticoid News and Research

RSS

Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

A new paper published in JAMA Network Open discusses the relationship between caffeine consumption in pregnancy and the future growth of the offspring.

1 Nov 2022

Does maternal obesity impact fetal brain development?

In a new study, researchers assessed the impact of maternal obesity on brain development in the fetus.

31 Oct 2022

Exploring SARS-CoV-2-associated endothelial dysfunction

A new study described the evidence, mechanisms, and therapies for endothelial dysfunction in coronavirus disease 2019 (COVID-19).

21 Oct 2022

Study uses pluripotent stem cell models to investigate stress response in PTSD patients

Stem cell-derived neurons from combat veterans with post-traumatic stress disorder (PTSD) react differently to a stress hormone than those from veterans without PTSD, a finding that could provide insights into how genetics can make someone more susceptible to developing PTSD following trauma exposure.

20 Oct 2022

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

A new study evaluated the current research on incidences of hypertension, new-onset diabetes mellitus, and dyslipidemia as possible sequelae of coronavirus disease 2019 (COVID-19).

18 Oct 2022

Two cases of acute abdominal pain in patients with COVID-19 in their second week of illness

Researchers described two cases of acute pain in the abdomen of patients with COVID-19.

17 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

Does maternal psychological and biological stress affect the composition of human breast milk?

Researchers investigated the influence of biological and psychological postpartum maternal stress on human milk fatty acid composition through a prospective cohort study in Amsterdam.

30 Sep 2022

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Researchers explored SARS-CoV-2 variants of concern/interest (VOC/VOI) kinetics and variations among non-hospitalized acute COVID-19 patients.

29 Sep 2022

How effective is vitamin D supplementation in COVID-19?

The current paper addresses the considerable evidence now supporting the efficacy of vitamin D in COVID-19, as well as its safety.

13 Sep 2022

Inhaled glucocorticoids linked to changes in brain matter

A recent BMJ Open study conducted a cross-sectional analysis to test the hypothesis that the usage of systemic and inhaled glucocorticoids was associated with alterations in grey matter volume (GMV) and white matter microstructure.

5 Sep 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Temporal changes in CD4 T-lymphocyte dynamics upon immunization against SARS-CoV-2 spike protein

Researchers assessed changes in CD4 T-lymphocyte temporal dynamics by evaluating T-lymphocyte responses to SARS-CoV-2 S using Foxp3-Tocky mice and Nr4a3-Tocky mice.

27 Jul 2022

$31 million PCORI funding for AAFP and Penn State to study the effectiveness of asthma treatments

The American Academy of Family Physicians, in partnership with Penn State College of Medicine, has been approved for a $31 million funding award by the Patient-Centered Outcomes Research Institute to study the comparative effectiveness of asthma treatments.

26 Jul 2022

The impact of glucocorticoid therapy on immune responses to COVID-19 vaccination or infection in rituximab-treated patients with autoimmune disorders

Researchers examined immune reactions to SARS-CoV-2)among B cell-depleted autoimmune patients who concomitantly administered glucocorticoids.

18 Jul 2022

Carbohydrates and polyphenols in prunes act as prebiotics to help reverse bone loss in mice

New research published in Nutrients provides evidence that prunes are a prebiotic food that reverses bone loss in mice.

13 Jul 2022

Study examines IMPACC trial results to understand clinical phenotypes of disease severity in hospitalized COVID-19 patients

In a recent article, longitudinal clinical phenotypes were described based on respiratory ordinal scales.

7 Jul 2022

Nonsurgical approach for treatment of children with rare skull tumor

Surgery can usually be avoided in children with a rare tumor of the skull, based on new research by investigators from Weill Cornell Medicine, NewYork-Presbyterian, Nicklaus Children's Hospital, the University of Texas Southwestern, the University of British Columbia and McGovern Medical School.

30 Jun 2022

Acute illness increases cortisol levels in children and adolescents

A new study reports that in children and adolescents without glucocorticoid deficiency, circulating cortisol levels were higher during acute illnesses.

28 Jun 2022

Brain motor and fear circuits orchestrate the immune response to acute stress

A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.

2 Jun 2022