Glucocorticoid is a compound that belongs to the family of compounds called corticosteroids (steroids). Glucocorticoids affect metabolism and have anti-inflammatory and immunosuppressive effects. They may be naturally produced (hormones) or synthetic (drugs).
A recent BMJ Open study conducted a cross-sectional analysis to test the hypothesis that the usage of systemic and inhaled glucocorticoids was associated with alterations in grey matter volume (GMV) and white matter microstructure.
Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.
Researchers assessed changes in CD4 T-lymphocyte temporal dynamics by evaluating T-lymphocyte responses to SARS-CoV-2 S using Foxp3-Tocky mice and Nr4a3-Tocky mice.
The American Academy of Family Physicians, in partnership with Penn State College of Medicine, has been approved for a $31 million funding award by the Patient-Centered Outcomes Research Institute to study the comparative effectiveness of asthma treatments.
Researchers examined immune reactions to SARS-CoV-2)among B cell-depleted autoimmune patients who concomitantly administered glucocorticoids.
New research published in Nutrients provides evidence that prunes are a prebiotic food that reverses bone loss in mice.
In a recent article, longitudinal clinical phenotypes were described based on respiratory ordinal scales.
Surgery can usually be avoided in children with a rare tumor of the skull, based on new research by investigators from Weill Cornell Medicine, NewYork-Presbyterian, Nicklaus Children's Hospital, the University of Texas Southwestern, the University of British Columbia and McGovern Medical School.
A new study reports that in children and adolescents without glucocorticoid deficiency, circulating cortisol levels were higher during acute illnesses.
A new study explores how acute stressors affected mice in terms of their immune responses in specific regions of the brain.
Isabella Salamone is an eighth-year student in the Driskill Graduate Program in Life Sciences (DGP) who is studying sexual dysmorphism in mice in the laboratory of Elizabeth McNally, MD, PhD, the Elizabeth J. Ward Professor of Genetic Medicine and director of the Center for Genetic Medicine.
There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.
Researchers assess the impact of interval administration of LD-IL-2 was examined in 18 T1D patients who received a three-day dosing interval.
A recent study by the TU Dresden and the University of Zurich in cooperation with the Max Planck Institute for the Science of Light establishes for the first time a link between depressive disorders and mechanical characteristics of all major blood cell types.
Obese mice that were fed a high-fat diet and that received prednisone one time per week had improved exercise endurance, got stronger, increased their lean body mass and lost weight, reports a new Northwestern Medicine study published in The Journal of Experimental Medicine.
Researchers reported the association of a single nucleotide polymorphism rs9984273 in the interferon-alpha/beta receptor gene with outcomes of acute respiratory distress syndrome and COVID-19.
Glucocorticoid steroids improved muscle performance through distinct, sex-specific molecular mechanisms in mice, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.
A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.
Voluntary fasting, for example interval fasting, is beneficial to health for many people, depending on their individual condition. For example, controlled periods of starvation can prevent and improve diseases such as diabetes and obesity.