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Cancer cells grown in tumor-mimicking environment can help predict the effect of experimental drugs

Before being tested in animals or humans, most cancer drugs are evaluated in tumor cells grown in a lab dish.

17 Apr 2019

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

Understanding the interactions between alcohol and cannabis can provide researchers, clinicians and other HCPs with important information on the severity of their side effects.

10 Apr 2019

New insight into anti-malaria drug

Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries. The effectiveness was investigated by the Chinese researcher Tu Youyou.

29 Jan 2019

Weakened metabolism of immune T cells may account for serious complications in elderly

The elderly suffer more serious complications from infections and benefit less from vaccination than the general population.

14 Dec 2018

Study opens up new possibilities for designing novel medicines

A study by the Computational Biochemistry Research Group of the Universitat Jaume I of Castellón, Spain, shows that enzyme activity depends on electrostatic properties, as opposed to mechanical ones.

11 Sep 2018

Effects of cancer-causing KRAS mutations more diverse than thought, shows study

The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a new study led by the University of Eastern Finland.

11 Sep 2018

Metabolic signatures in blood may help in earlier diagnosis of autism, shows research

Metabolic signatures in the blood of children with autism spectrum disorder may lead to earlier diagnosis of the condition for some children, according to newly published research. These biochemical signatures provide insight into how the body metabolizes certain amino acids important to typical neurodevelopment.

6 Sep 2018

Research reveals new gears in the circadian clock

A long-studied factor controlling human sleep cycles actually has two forms, one that keeps a key protein stable and another that promotes its degradation.

12 Jul 2018

Scientists decipher workings of little-understood bacterial riboswitch

In a discovery that points to potential new antibiotic medicines, scientists from Rice University and the University of Michigan have deciphered the workings of a common but little-understood bacterial switch that cuts off protein production before it begins.

22 May 2018

Artificial antimicrobial peptides may help fight against drug-resistant bacteria

During the past several years, many strains of bacteria have become resistant to existing antibiotics, and very few new drugs have been added to the antibiotic arsenal.

16 Apr 2018

Biophysical mechanism involving spaghetti-like proteins helps cells avoid 'data breaches'

Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert Einstein College of Medicine have shown.

28 Mar 2018

Certain foods may assist spread of breast cancer

Researchers from Cambridge have come up with a new study that shows that some foods may influence the spread of certain cancers. Asparagine for example is a nutrient present in asparagus. If this nutrient is absent, the growth of breast cancer can be slowed, they note. The results of the study are published in the latest issue of the journal Nature.

8 Feb 2018

Unique mechanism of drug resistance found in pandemic cholera

Cholera is a devastating disease for millions worldwide, primarily in developing countries, and the dominant type of cholera today is naturally resistant to one type of antibiotic usually used as a treatment of last resort.

3 Jan 2018

Study finds potential chemical compound that initiated life on Earth

A new study conducted at The Scripps Research Institute (TSRI) has found a compound called diamidophosphate (DAP), which is expected to have played a vital role in the origins of life on Earth.

8 Nov 2017

Study finds link between increased brain glucose levels and Alzheimer's

A new study published yesterday in Alzheimer's & Dementia: the Journal of the Alzheimer's Association, found a link for the first time between abnormalities in the mechanism of glucose breakdown in the brain and the severity of tangles and amyloid plaques in the brain, as well as the commencement of visible symptoms of Alzheimer's disease.

7 Nov 2017

Nicotine alters gut microbiome differently in males and females, mice study shows

Many people who smoke or chew tobacco can't seem to escape nicotine's addictive properties. Studies show that women in particular seem to have a harder time quitting, even with assistance, when compared to men.

3 Nov 2017

Study finds brain chemical elevations in young people experiencing first episode of psychosis

A new study of young people experiencing a first episode of psychosis reports elevations in the brain chemicals glutamate and glycine. Published in Biological Psychiatry, the study led by Dr. Dost öngür of Harvard Medical School provides the first-ever measurement of glycine levels in patients with psychotic disorders.

11 Oct 2017

Researchers demonstrate potential of new PET tracer for imaging prostate cancer

In the featured translational article in the August issue of The Journal of Nuclear Medicine, researchers at the University of Michigan demonstrate the potential of a new PET tracer, Carbon-11 labeled sarcosine (11C-sarcosine), for imaging prostate cancer, and set the stage for its possible use in monitoring other cancers.

7 Aug 2017

Antiperspirants can be safely used during breast radiotherapy, study suggests

Women undergoing daily radiation therapy for breast cancer are commonly told they should not use antiperspirant for fear that it could cause greater radiation damage to the skin, but a new study from the Perelman School of Medicine at the University of Pennsylvania shows that advice is not based on sound science.

24 Jul 2017

Scientists reveal key role of excess gut calcium in C. diff infections

It lurks in hospitals and nursing homes, surviving the cleaning crew's attempt to kill it by holing up in a tiny hard shell. It preys upon patients already weak from disease or advanced age.

13 Jul 2017