Glycoprotein News and Research

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Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Researchers assessed the ability of spike proteins from 24 animal or human coronaviruses to utilize angiotensin-converting enzyme 2.

5 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Epigenome reprogramming after SARS-CoV-2 infection

Researchers performed a 3D evaluation of SARS-CoV-2 infected human cells.

27 Mar 2023

Researchers discover a new switching point that regulates hemostasis and thrombosis

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential.

24 Mar 2023

Candidate hepatitis C mRNA vaccine induces protective immunity in animal model

In a recent study published in the npj vaccines journal, researchers assessed the immune protection elicited by messenger ribonucleic acid (mRNA) vaccines delivering Hepatitis C virus (HCV) E1 and modified E2.

23 Mar 2023

Emergence and persistency of SARS-CoV-2 Omicron BA.2.3.7 in Taiwan

Researchers utilize whole-genome surveillance to monitor community transmission and evolution of SARS-CoV-2 in Taiwan.

22 Mar 2023

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Researchers assess SARS-CoV-2 spike protein-specific immunological memory among unvaccinated and vaccinated convalescents.

22 Mar 2023

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

In a recent study published in the journal Nutrients, researchers at Johns Hopkins Medicine reviewed the beneficial properties of green tea in alleviating symptoms of benign gynecological disorders.

21 Mar 2023

Playing tackle football at an early age increases risk for brain decline later

The degenerative brain disease known as CTE, or chronic traumatic encephalopathy, has become a specter haunting football.

20 Mar 2023

Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

What is the effect of low Anti-Müllerian hormone on semen quality?

A recent BMC Medicine study investigated the relationship between Vitamin D and serum Anti-Müllerian hormone (AMH) in infertile men. This study was based on secondary analysis of a randomized clinical trial, which assessed the effect of high-dose Vitamin D plus calcium and placebo on semen quality in Vitamin D deficient infertile men.

10 Mar 2023

Early safety and efficacy results on a contraceptive vaginal film that inactivates sperm

The current study aimed to explore the contraceptive potential of the human contraceptive antibody-containing vaginal film called ZB-06.

7 Mar 2023

Roadmap outlines a framework for moving COVID-19 vaccines forward

Researchers presented the coronavirus vaccines research and development roadmap to promote the development of broadly protective COVID-19 vaccines.

24 Feb 2023

How effective has the bivalent booster COVID vaccination been?

In a recent study published in the journal Eurosurveillance, researchers estimated the effectiveness of bivalent messenger ribonucleic acid (mRNA) vaccines targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 subvariant and the original Wuhan-Hu1 strain against Omicron infections in the vaccinated population of the Netherlands between 26 September and 19 December 2022.

19 Feb 2023

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Researchers determined the prevalence of antibodies against the SARS-CoV-2 spike glycoprotein following three or more doses of COVID-19 vaccines among immunocompromised individuals.

17 Feb 2023

Whole-genome CRISPR activation for the identification of host factors controlling cellular interactions with SARS-CoV-2

Researchers found that LRRC15, a TLR-related cell surface receptor, blocked SARS-CoV-2 spike binding.

13 Feb 2023

Study demonstrates antiviral effects of vinegar against SARS-CoV-2

A study published in the journal PLOS ONE demonstrates the effectiveness of acetic acid, the main component of vinegar, in inactivating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.