Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Drug reviparin reduces the risk of death after heart attack

The drug reviparin (a low molecular weight heparin anticoagulant), when administered to patients with a heart attack, is effective in reducing the risk of death and the risk of a subsequent heart attack, according to a study in the January 26 issue of JAMA.

26 Jan 2005

Medicine alone may not offer best quality of life for patients with moderate heart attack risk

Routine angiography and revascularization procedures, if indicated, appear to offer better quality of life than conservative medical treatment for patients with chest pain and evidence of coronary artery disease, according to a new study (PDF file) in the Jan. 18, 2005 issue of the Journal of the American College of Cardiology.

19 Jan 2005

Physicians should avoid prescribing Bextra altogether

Physicians should avoid prescribing Bextra altogether, or use it only as a drug of last resort, says a researcher from Wake Forest University Baptist Medical Center and colleagues in an editorial published on-line Jan. 17 in Circulation, a publication of the American Heart Association.

19 Jan 2005

Animal study on vascular effects of COX-2 inhibition

In an article by Egan et al, titled, "Cyclooxygenases, Thromboxane, and Atherosclerosis," published in the Jan 17 issue of Circulation: Journal of the American Heart Association researchers examined some of the molecular mechanisms of drugs affecting prostaglandin and thromboxane production.

17 Jan 2005

Further evidence for the role of cyclooxygenases (COX) in heart-disease risk

In two articles, published in Circulation, researchers from the University of Pennsylvania School of Medicine provide further evidence for the role of cyclooxygenases (COX) in heart-disease risk.

17 Jan 2005

Patient drawings important diagnostic tool for heart attack recovery

Simple drawings by heart attack victims of what they believe has happened to their heart may be an important diagnostic tool to aid their recovery, research at The University of Auckland has shown.

17 Jan 2005

Millions of Canadians at risk because of avoidable delays in diagnosis and treatment of high blood pressure

New guidelines released by the Canadian Heart and Stroke Foundation reveal the health of millions of Canadians is being placed at risk because of avoidable delays in diagnosis and treatment of high blood pressure (hypertension).

17 Jan 2005

Heart attacks in women not being picked up

Women are still less likely than men to be correctly identified as having had a heart attack, despite the publication of new guidance designed to lower the index of suspicion, reveals research in Heart.

16 Jan 2005

Reducing levels of smoking, cholesterol and blood pressure will halve current CHD mortality

A new Health Development Agency briefing paper, ‘Relative contributions of changes in risk factors and treatment to the reduction in coronary heart disease mortality’ highlights that even a small reduction in the current levels of cholesterol, smoking and blood pressure, could save approximately 50,000 lives annually in England and Wales.

12 Jan 2005

Recent study correlates human cord blood cells with reduced animal heart attack damage

Researchers from the University of South Florida (USF) and James A. Haley Veterans Hospital have reported in the journal "Cell Transplantation" that stem cells from umbilical cord blood effectively treated heart attacks in an animal study.

12 Jan 2005

Scientists identify a protein that regulates alcohol-withdrawal seizures

Seizures are the most life-threatening, as well as disconcerting, symptoms of withdrawal in people who are alcoholics and who abruptly stop drinking. Heavy consumption of alcohol, or ethanol, the substance in beer, wine and liquor that is addictive, leads to changes in the brain.

10 Jan 2005

Statins lower C-reactive protein (CRP), a major new risk factor for heart disease marked by inflammation

For years, doctors have believed that statin therapy lowers the risk of heart disease solely by lowering levels of cholesterol.

9 Jan 2005

Trial of naproxen and celecoxib suspended

Use of study drugs in a large, federally funded Alzheimer prevention trial has been suspended following a decision by the study's leadership on Dec. 17, 2004.

9 Jan 2005

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

5 Jan 2005

Metabolic syndrome linked to carbohydrate-rich diet

Metabolic Syndrome, a health condition characterized by obesity, high cholesterol levels, elevated blood pressure and pre-diabetes, presently affects nearly 47 million Americans.

5 Jan 2005

Stem cells from umbilical cord blood effectively treated heart attacks

When injected into rats' hearts soon after a heart attack, stem cells taken from human umbilical cord blood (HUCB) greatly reduced the size of heart damage and restored pumping function to near normal. This improvement occurred without the need for drugs to prevent the rats' immune system from rejecting the human cells.

5 Jan 2005

Depression can double the risk of death or repeat heart disease in heart attack patients

Depression can double the risk of death or repeat heart disease in heart attack patients, according to two reviews of more than 40 studies that examine the link between depression and heart disease. The reviews are published in the journal Psychosomatic Medicine.

5 Jan 2005

Study to compare traditional and spiritual post-heart attack recovery approaches

Surviving a heart attack is a frightening experience, one that can change a person for life. Even having severe heart-related chest pain can wake a person up to his or her mortality.

4 Jan 2005

Angioplasty may replace bypass for more patients who are also receiving a new heart valve

The death rate during combination surgery to bypass clogged coronary arteries and simultaneously replace a heart valve in very sick patients can be as high as one in five, but a review of records of very sick patients who underwent balloon angioplasty, followed by heart valve replacement surgery, found only one death among 26 patients.

4 Jan 2005

3 or more alcoholic drinks increases risk of ischemic stroke by 45%

A new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and the Harvard School of Public Health (HSPH) has found that heavy drinkers -- men who consume an average of three or more alcoholic beverages per day -- are nearly 45 percent more likely to suffer an ischemic stroke compared with nondrinkers.

4 Jan 2005

Heart Attack (Myocardial Infarction) News and Research

Further Reading

Drug reviparin reduces the risk of death after heart attack

Medicine alone may not offer best quality of life for patients with moderate heart attack risk

Physicians should avoid prescribing Bextra altogether

Animal study on vascular effects of COX-2 inhibition

Further evidence for the role of cyclooxygenases (COX) in heart-disease risk

Patient drawings important diagnostic tool for heart attack recovery

Millions of Canadians at risk because of avoidable delays in diagnosis and treatment of high blood pressure

Heart attacks in women not being picked up

Reducing levels of smoking, cholesterol and blood pressure will halve current CHD mortality

Recent study correlates human cord blood cells with reduced animal heart attack damage

Scientists identify a protein that regulates alcohol-withdrawal seizures

Statins lower C-reactive protein (CRP), a major new risk factor for heart disease marked by inflammation

Trial of naproxen and celecoxib suspended

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Metabolic syndrome linked to carbohydrate-rich diet

Stem cells from umbilical cord blood effectively treated heart attacks

Depression can double the risk of death or repeat heart disease in heart attack patients

Study to compare traditional and spiritual post-heart attack recovery approaches

Angioplasty may replace bypass for more patients who are also receiving a new heart valve

3 or more alcoholic drinks increases risk of ischemic stroke by 45%

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