Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

High levels of a blood protein called mannose-binding lectin (MBL) are associated with lower risk of heart attack, particularly among diabetics, report Saevardottir and colleagues.

28 Dec 2004

Public health advisory for the use of non-steroidal anti-inflammatory drug products

The Food and Drug Administration (FDA) has issued a Public Health Advisory summarizing the agency's recent recommendations concerning the use of non-steroidal anti-inflammatory drug products (NSAIDs), including those known as COX-2 selective agents.

23 Dec 2004

May soon be possible to identify people at risk and even to treat a heart problem with a drug that works on the brain

Sudden cardiac death from emotional stress may be triggered by uneven signals from the brain to the heart, according to a study by University College London (UCL) scientists published in the January issue of Brain.

23 Dec 2004

Arthritis drug caution advised by New Zealand experts

An expert New Zealand committee reviewing the safety of a group of arthritis drugs called COX-2 inhibitors has reinforced UK advice cautioning against their routine use where safe and effective alternatives are available.

21 Dec 2004

New advice on anti-inflammatory drugs called Cox-2 Inhibitors, including Celebrex

Patients who are taking Celebrex, Bextra and Arcoxia should make a non-urgent appointment with their GP to review their treatment. Patients who have established heart disease or who are at high risk of stroke will have their treatment changed.

21 Dec 2004

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Cardiovascular disease risk is extremely high in adults with diabetes. Yet women as well as people under 50 who have diabetes do not use aspirin, despite the fact that aspirin has been found an effective and inexpensive means to reduce risk of first and subsequent heart attack.

20 Dec 2004

Size of myocardial infarct measured using MRI

In animal studies, researchers at Johns Hopkins have effectively used magnetic resonance imaging (MRI) to measure with 94 percent accuracy the size and amount of heart muscle damaged by a heart attack, known in medical terms as a myocardial infarct, or m.i., for short.

20 Dec 2004

Advice for patients who have been taking Celebrex or Bextra

The recent announcement that Celebrex, a popular pain drug in the same family as Vioxx, has been found to pose an increased risk of heart problems is bound to leave many pain patients stunned, confused and worried.

20 Dec 2004

Celebrex suspension

The National Institutes of Health (NIH) announced that it has suspended the use of COX-2 inhibitor celecoxib (Celebrex™ Pfizer, Inc.) for all participants in a large colorectal cancer prevention clinical trial conducted by the National Cancer Institute (NCI).

19 Dec 2004

High pressure work deadlines boost heart attack risk six-fold

A high pressure work deadline boosts the chances of a heart attack within the next 24 hours by a factor of six, reveals research in the Journal of Epidemiology and Community Health.

13 Dec 2004

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

The risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs, according to an article in the December issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

13 Dec 2004

Greater risk of heart attack associated with Vioxx than Celebrex

In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a greater risk of heart attack associated with Vioxx than Celebrex, although neither of the two drugs showed a statistically significant elevated risk of heart attack relative to people who did not use the drugs.

8 Dec 2004

New insight into anticoagulation therapies

Anticoagulation therapies, or treatments that reduce the amount of clotting factors in the blood, are quite common and used for a variety of reasons.

6 Dec 2004

Heart Hospital begins experimental cell therapy

Physicians at the Heart Hospital became the first team in the UK to treat a patient with an experimental new therapy designed to repair damage to cardiac muscle resulting from a heart attack. If successful, this treatment would give doctors the ability to improve the hearts of people with heart failure, rather than just treating the symptoms.

6 Dec 2004

Heart researchers have used gene therapy to bring failing rat hearts back to normal

Scientists led by Walter Koch, Ph.D., director of the Center for Translational Medicine in the Department of Medicine in Jefferson Medical College of Thomas Jefferson University in Philadelphia, used a virus to insert the gene for a protein called S100A1 into failing rat hearts.

4 Dec 2004

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Type 1 diabetes could be prevented by a new nasal insulin vaccine

A world-leading medical trial conducted in Melbourne suggests that the onset of type 1 diabetes could be prevented in many at-risk people by a new nasal insulin vaccine.

29 Nov 2004

Elevated BMI may not increase risk of death among men with heart attack or stroke

BMI, or body mass index, is considered an indicator of both mortality and heart attack risk among middle-aged and older men free of major diseases. However, the impact of BMI on mortality in men who have already had a heart attack or stroke has not been clearly established.

29 Nov 2004

Weight gain beginning in childhood can lead to an enlarged heart

Weight gain beginning in childhood can lead to an enlarged heart by early adulthood, researchers reported in Circulation: Journal of the American Heart Association.

24 Nov 2004

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries, according to a study in Circulation: Journal of the American Heart Association.

24 Nov 2004

Heart Attack (Myocardial Infarction) News and Research

Further Reading

High levels of a blood protein called mannose-binding lectin associated with lower risk of heart attack

Public health advisory for the use of non-steroidal anti-inflammatory drug products

May soon be possible to identify people at risk and even to treat a heart problem with a drug that works on the brain

Arthritis drug caution advised by New Zealand experts

New advice on anti-inflammatory drugs called Cox-2 Inhibitors, including Celebrex

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Size of myocardial infarct measured using MRI

Advice for patients who have been taking Celebrex or Bextra

Celebrex suspension

High pressure work deadlines boost heart attack risk six-fold

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

Greater risk of heart attack associated with Vioxx than Celebrex

New insight into anticoagulation therapies

Heart Hospital begins experimental cell therapy

Heart researchers have used gene therapy to bring failing rat hearts back to normal

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Type 1 diabetes could be prevented by a new nasal insulin vaccine

Elevated BMI may not increase risk of death among men with heart attack or stroke

Weight gain beginning in childhood can lead to an enlarged heart

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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