Hemoglobin News and Research

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Orexigen Therapeutics announces submission of Contrave NDA for treatment of obesity

Orexigen® Therapeutics, Inc. announced that the Company has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for Contrave® (naltrexone SR/bupropion SR), its investigational drug for the treatment of obesity. The NDA is based on a substantial body of evidence gathered through the Contrave Obesity Research (COR) clinical program, which included over 4,500 patients.

1 Apr 2010

NKF 2010 Spring Clinical Meeting: Multiple posters on Hematide/peginesatide to be presented

Affymax, Inc. and Takeda Pharmaceuticals Global Research & Development Center, Inc., U.S., today announced multiple posters on Hematide™/peginesatide have been accepted for presentation at the National Kidney Foundation (NKF) 2010 Spring Clinical Meeting taking place April 13-17, 2010 in Orlando, Florida. Hematide is an investigational agent for the treatment of anemia in chronic renal failure (also referred to as renal anemia).

31 Mar 2010

Positive data from Shire's Phase III trial of TKT-034 in Type 1 Gaucher disease patients who switched to VPRIV

Shire plc, the global specialty biopharmaceutical company, today presented positive data from a Phase III clinical trial (TKT-034) designed to evaluate the safety of switching to VPRIV (velaglucerase alfa for injection), from imiglucerase, as well as an interim analysis of safety data from an ongoing multicenter open-label treatment protocol (HGT-GCB-058) implemented to provide VPRIV to patients affected by the continuing shortage of imiglucerase.

26 Mar 2010

FDA approves OrSense's NBM-200MP non-invasive oximetry and low signal oximetry sensor

OrSense Ltd., developer of monitors for non-invasive measurements of various blood parameters, announced today it has received U.S. Food and Drug Administration (FDA) approval for NBM-200MP, a non-invasive oximetry and low signal oximetry sensor.

23 Mar 2010

Somanetics first-quarter 2010 net revenues up 18%

Somanetics Corporation reported net revenues of $13.1 million for the first quarter ended February 28, 2010, an 18 percent increase from $11.2 million in the same period of 2009.

17 Mar 2010

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Babies born to mothers with obesity and exposed to passive smoking are more likely to have health problems than others. This conclusion is based on evidence of elevated levels of nucleated red blood cells in the umbilical cord reported in the International Journal of Food Safety, Nutrition and Public Health.

17 Mar 2010

Arthritis drug could be useful for treating patients with type 2 diabetes

Clinical studies of a generic drug called salsalate, widely prescribed for arthritis, now provide early promising results that it may be useful for the treatment of patients with type 2 diabetes as well.

16 Mar 2010

Early administration of metformin can prevent long-term complications of diabetes: Study

The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association.

10 Mar 2010

Bristol-Myers Squibb, AstraZeneca commence SAVOR-TIMI 53 trial of ONGLYZA for type 2 diabetes

Bristol-Myers Squibb Company and AstraZeneca today announced the commencement of the “Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus” trial, a multicenter, randomized, double-blind, placebo-controlled Phase 4 study, to evaluate treatment with ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 inhibitor, in adult type 2 diabetes patients with cardiovascular risk factors.

10 Mar 2010

Orexigen Therapeutics reports net loss of $15.0M for three months ended December 31, 2009

Orexigen® Therapeutics, Inc., a biopharmaceutical company focused on the treatment of obesity, today announced financial results for the three months and year ended December 31, 2009.

9 Mar 2010

HbA1c levels help predict future diabetes more accurately than fasting glucose measurements

Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Mar 2010

Concordia University Professor awarded grant to study molecular mechanisms of virulence factor protein

Concordia University is pleased to announce that Dr. Peter D. Pawelek, Assistant Professor, Department of Chemistry and Biochemistry was awarded a grant from the Thalassemia Foundation of Canada to study molecular mechanisms of a virulence factor protein from an opportunistic pathogen that affects thalassemia patients.

3 Mar 2010

PointCare Technologies donates rapid PointCare NOW tests to Haitian clinics

PointCare Technologies, pioneer inventor of a portable diagnostic system that enables effective HIV/AIDS monitoring for millions of people in remote areas of developing countries, has donated 4,000 (a month's supply) of its rapid PointCare NOW tests to Haitian clinics to ensure the resumption of critical care to HIV/AIDS patients.

24 Feb 2010

A1C lab test can help in combating diabetes

Approximately 57 million Americans are on the brink of diabetes. Yet research tells us that there is much we can do to keep it from progressing to full-blown diabetes. Lab tests can help us get a grip on the disease, says the American Clinical Laboratory Association President Alan Mertz.

24 Feb 2010

Study to restrict hemoglobin-based oxygen carriers

study published in the March 2010 issue of the journal Anesthesiology gives researchers new insights in how to better understand and control a severe side effect of hemoglobin-based oxygen carriers (HBOCs), often referred to as "artificial blood."

23 Feb 2010

Two genetic alterations linked to benign enzyme condition keep hepatitis C patients anemia-free

Many people who undergo treatment for hepatitis C develop hemolytic anemia, a disorder that destroys red blood cells. In some cases, it is so severe they have to reduce their medication or stop therapy altogether. But now, scientists in Duke University's Institute for Genome Sciences & Policy have discovered two genetic alterations linked to a benign enzyme condition that keep some patients anemia-free.

21 Feb 2010

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Today the National Business Coalition on Health issued its annual report on how America's health plans are doing to improve care and control costs for diabetes. The analysis is based on health plan survey data from NBCH's eValue8™ program, the nation's leading Request for Information (RFI) tool used by employers, coalitions and their purchaser members to set expectations and measure health plan performance.

19 Feb 2010

Blood transfusions based on single low hematocrit measurement questioned

A comparison study of nearly 1,900 patients published in Perfusion, a peer-reviewed academic journal, questions the long-standing practice of basing blood transfusion decisions on a single low hematocrit measurement result. In the study, titled Is it the Patient or the Physician who Cannot Tolerate Anemia?, researchers showed that a single measure of hematocrit is not a reliable indicator of transfusion need and that lower-than-normal hemoglobin levels have no adverse impact on patients.

19 Feb 2010

Six states to study sickle cell disease and thalassemias in national pilot project

Medical researchers are developing a new surveillance system to determine the number of patients diagnosed with a family of inherited blood disorders known as hemoglobinopathies, including sickle cell disease, thalassemias, and hemoglobin E disease.

19 Feb 2010

Special issue reviews current state of science in fetal therapy

Repairing birth defects in the womb. Inserting a tiny laser into the mother's uterus to seal off an abnormal blood flow and save fetal twins. Advancing the science that may allow doctors to deliver cells or DNA to treat sickle cell anemia and other genetic diseases before birth.

17 Feb 2010

Hemoglobin News and Research

Orexigen Therapeutics announces submission of Contrave NDA for treatment of obesity

NKF 2010 Spring Clinical Meeting: Multiple posters on Hematide/peginesatide to be presented

Positive data from Shire's Phase III trial of TKT-034 in Type 1 Gaucher disease patients who switched to VPRIV

FDA approves OrSense's NBM-200MP non-invasive oximetry and low signal oximetry sensor

Somanetics first-quarter 2010 net revenues up 18%

Obesity and passive smoking are risk factors for elevated umbilical cord neonatal immature

Arthritis drug could be useful for treating patients with type 2 diabetes

Early administration of metformin can prevent long-term complications of diabetes: Study

Bristol-Myers Squibb, AstraZeneca commence SAVOR-TIMI 53 trial of ONGLYZA for type 2 diabetes

Orexigen Therapeutics reports net loss of $15.0M for three months ended December 31, 2009

HbA1c levels help predict future diabetes more accurately than fasting glucose measurements

Concordia University Professor awarded grant to study molecular mechanisms of virulence factor protein

PointCare Technologies donates rapid PointCare NOW tests to Haitian clinics

A1C lab test can help in combating diabetes

Study to restrict hemoglobin-based oxygen carriers

Two genetic alterations linked to benign enzyme condition keep hepatitis C patients anemia-free

NBCH's annual report: How America's health plans are doing to improve care and control costs for diabetes

Blood transfusions based on single low hematocrit measurement questioned

Six states to study sickle cell disease and thalassemias in national pilot project

Special issue reviews current state of science in fetal therapy

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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