Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Women with a history of hypothyroidism at greater risk of developing liver cancer

Women with a history of hypothyroidism face a significantly higher risk of developing liver cancer, according to a new study in the May issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience.

4 May 2009

Study examines radiation dose estimates for pregnant women undergoing therapeutic ERCP

Pregnant women with gallstone disease may require immediate endoscopic intervention because of potentially life-threatening cholangitis (infection in the bile ducts) or gallstone pancreatitis (inflammation of the pancreas).

30 Apr 2009

Roche and Pharmasset start phase IIb clinical trial of R7128 nucleoside polymerase inhibitor for chronic hepatitis C

Pharmasset, Inc. and Roche have announced that the first patient has been dosed in a Phase IIb study of R7128, the nucleoside polymerase inhibitor most advanced in development for the treatment of chronic hepatitis C (HCV).

26 Apr 2009

Transplant physicians express serious concern about organ procurement practices in China

The globalization of health care and the growth of "transplant tourism" (traveling abroad to purchase donor organs and undergo organ transplantation) have outpaced the implementation of internationally accepted ethical standards for procurement of organs for transplantation.

22 Apr 2009

Early treatment for hepatitis C offers a good chance of a cure

Australian researchers say as many as 70% of hepatitis C carriers can possibly be cured of the disease with early treatment - this is excellent news as hepatitis C, if left untreated can lead to serious liver disease.

22 Apr 2009

Possible increase in colon cancer after start of folic acid fortification

The rate of colorectal cancer in Chile may have increased since that country began fortifying wheat flour with folic acid, reports a study in the European Journal of Gastroenterology & Hepatology.

5 Apr 2009

Varicella zoster infection causes severe autoimmune hepatitis

Autoimmune hepatitis (AIH) is a chronic liver inflammation of unknown etiology that is characterized by the presence of circulatory autoantibodies and ongoing liver tissue damage.

2 Apr 2009

Colonoscopy versus virtual colonoscopy

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

2 Apr 2009

Research looks at the elimination of hepatitis B and C

Two new studies in the April issue of Hepatology explore the ways that hepatitis B virus (HBV) and hepatitis C virus (HCV) can be cleared from patients' bodies.

1 Apr 2009

Sorafenib may help patients suffering from advanced portal hypertension

In a new study, a therapeutic agent called sorafenib dramatically improved the condition of rats with portal hypertension.

1 Apr 2009

How fat is stored may explain lower rate of liver disease in African-Americans

Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty liver disease, researchers at UT Southwestern Medical Center have found.

29 Mar 2009

Difference in fat storage may explain lower rate of liver disease in African-Americans

29 Mar 2009

Researchers investigate new way to block reproduction of the hepatitis C virus

Massachusetts General Hospital (MGH) researchers are investigating a new way to block reproduction of the hepatitis C virus (HCV) - targeting not the virus itself but the human genes the virus exploits in its life cycle.

20 Mar 2009

Colonoscopy and virtual colonoscopy, either way get screened!

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

3 Mar 2009

Link between, bacteria, cancer explored with funding from American Cancer Society

The role of bacteria in the development of colorectal cancer is coming under scrutiny at the University of Rochester Medical Center, thanks to an $840,000 research award from the American Cancer Society.

3 Mar 2009

Liver tumors associated with metabolic syndrome differ from other tumors

Liver cancer in patients whose only risk factor is metabolic syndrome has distinct forms and structures compared to other liver tumors.

25 Feb 2009

Ethnic differences found for fatty liver disease and insulin resistance

A new study suggests that the metabolic response to obesity and insulin resistance, particularly as it pertains to the liver, differs among ethnic groups in the U.S. African-Americans are more resistant to the buildup of fat in the abdominal adipose tissue and liver, and to high triglyceride levels associated with insulin resistance.

25 Feb 2009

Discovery of 'obesity gene' involved in weight gain response to high-fat diet

Scientists have determined that a specific gene plays a role in the weight-gain response to a high-fat diet.

24 Feb 2009

Researchers show how immune system reacts to a hepatitis B infection

Researchers at the Helmholtz Centre in Braunschweig demonstrate how the immune system reacts to a hepatitis B infection.

17 Feb 2009

Weight loss improves nonalcoholic steatohepatitis

In a recent study, Saint Louis University researchers found that weight loss of at least 9 percent helped patients reverse a type of liver disease known as nonalcoholic steatohepatitis (NASH), a finding that will allow doctors to give patients specific weight-loss goals that are likely to improve their livers.

17 Feb 2009