Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Newborn neurons in the adult brain can settle in the wrong neighborhood

A new study published in this week's PLoS Biology could have significant consequences for neural tissue transplantation to treat brain injuries or neural degeneration.

11 Nov 2008

Newborn neurons in the adult brain can settle in the wrong neighborhood

In a study that could have significant consequences for neural tissue transplantation strategies, researchers at the Salk Institute for Biological Studies report that inactivating a specific gene in adult neural stem cells makes nerve cells emerging from those precursors form connections in the wrong part of the adult brain.

11 Nov 2008

Memory function varies after damage to key area of the brain

Scientists at the University of Liverpool have discovered dramatic differences in the memory performance of patients with damage to the hippocampus, an area of the human brain key to memory.

23 Oct 2008

Fatty acids may be the culprit in Alzheimer's

According to new research from the U.S. controlling the level of a fatty acid in the brain could help treat Alzheimer's disease (AD).

21 Oct 2008

The underdevelopment of a specific brain region may cause schizophrenia

The underdevelopment of a specific region in the brain may lead to schizophrenia in individuals. According to research published today in BioMed Central's open access journal Molecular Brain, dentate gyrus, which is located in the hippocampus in the brain and thought to be responsible for working memory and mood regulation, remained immature in an animal model of schizophrenia.

10 Sep 2008

Exercise reduces damage after therapeutic irradiation to the brain

Researchers at the Sahlgrenska Academy in Gothenburg show for the first time that exercise helps restore stem cell growth and improves behavior in young mice that suffered damage to the brain induced by a clinically relevant dose of radiation. The researchers believe that these results are also applicable to children that have suffered damage due to radiotherapy of brain tumors.

3 Sep 2008

Vitamin B deficiency may cause vascular cognitive impairment

A deficiency of B-vitamins may cause vascular cognitive impairment, according to a new study. Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University used an experimental model to examine the metabolic, cognitive, and microvascular effects of dietary B-vitamin deficiency.

2 Sep 2008

Molecular switch provides insights into a form of altered brain activity occurring in schizophrenia

People with schizophrenia have an alteration in a pattern of brain electrical activity associated with learning and memory. Now, researchers from the National Institutes of Health and Sweden's Karolinska Institute have identified in mouse brain tissue a molecular switch that, when thrown, increases the strength of this electrical pattern. The researchers found that adding the brain chemical Neuregulin-1 to the brain tissue boosted the electrical signals that the tissue generated.

13 Aug 2008

Estrogen treatments may sharpen mental performance in some women

Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear cognitive cobwebs.

29 Jul 2008

Healthy children of Alzheimer's patients show early brain changes

Medical College of Wisconsin researchers in Milwaukee have reported that children of Alzheimer's patients who are carriers of a genetic risk factor for Alzheimer's disease have neurological changes that are detectable long before clinical symptoms may appear.

29 Jul 2008

Aging impairs the consolidation of memories during sleep

Aging impairs the consolidation of memories during sleep, a process important in converting new memories into long-term ones, according to new animal research in the July 30 issue of The Journal of Neuroscience. The findings shed light on normal memory mechanisms and how they are disrupted by aging.

29 Jul 2008

Exercise shown to slow down Alzheimer's progress

According to a new study, patients with the early signs of Alzheimer's disease had less deterioration in the areas of the brain which control memory, if they exercised regularly.

28 Jul 2008

Physical fitness levels influence brain atrophy in Alzheimer's

People with early Alzheimer's disease who had better fitness ratings had less atrophy in key brain areas associated with memory, according to research reported today at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2008) in Chicago.

27 Jul 2008

Amyloid plaques seen with conventional MRI in animal model for first time

For the first time, scientists have captured images of brain lesions similar to those found in Alzheimer's disease using clinical-grade MRI in an animal model of the disease, according to research reported at the Alzheimer's Association's 2008 International Conference on Alzheimer's Disease (ICAD 2008), in Chicago.

27 Jul 2008

Stem cells help keep the brain healthy and active

For some years, scientists have been speculating over why stem cells exist in the brain, as brain regeneration is limited. A German team of neuroscientists believe these stem cells help keep the brain healthy and active.

13 Jul 2008

Researchers discover that learning suffers if brain transcript isn't transported far out to end of neurons

Neuroscientists at Georgetown University Medical Center have solved a mystery that lies at the heart of human learning, and they say the solution may help explain some forms of mental retardation as well as provide clues to overall brain functioning.

10 Jul 2008

An analysis of food's affect on the brain

In addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders.

9 Jul 2008

Stopping drinking may lead to health problems including depression

Scientific evidence has long suggested that moderate drinking offers some protection against heart disease, certain types of stroke and some forms of cancer.

8 Jul 2008

Hydrogen sulfide significantly improves survival after extreme blood loss

For the first time, researchers have demonstrated that the administration of minute amounts of inhaled or intravenous hydrogen sulfide, or H2S - the molecule that gives rotten eggs their sulfurous stench - significantly improves survival from extreme blood loss in rats.

1 Jul 2008

Protein Ronin shown to be an alternate control for embryonic stem cells

Like the masterless samurai for whom it is named, the protein Ronin chooses an independent path, maintaining embryonic stem cells in their undifferentiated state and playing essential roles in genesis of embryos and their development, said Baylor College of Medicine researchers who reported on this novel cellular regulator in the current issue of the journal Cell.

27 Jun 2008