Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Selective activation of the dentate gyrus can reduce anxiety without affecting learning

Columbia University Medical Center (CUMC) researchers have found the first evidence that selective activation of the dentate gyrus, a portion of the hippocampus, can reduce anxiety without affecting learning.

7 Mar 2013

Schizophrenic people with MIR137 tend to develop illness at younger age

Some of the dramatic differences seen among patients with schizophrenia may be explained by a single gene that regulates a group of other schizophrenia risk genes. These findings appear in a new imaging-genetics study from the Centre for Addiction and Mental Health (CAMH).

5 Mar 2013

Study opens possibility for creating animal models of memory disorders

If you ask a rat whether it knows how it came to acquire a certain coveted piece of chocolate, Indiana University neuroscientists conclude, the answer is a resounding, "Yes." A study newly published in the journal Current Biology offers the first evidence of source memory in a nonhuman animal.

27 Feb 2013

Loss of Dickopf-1 restores neurogenesis and memory in animal model

Loss of the molecule Dickopf-1 in the hippocampus in older animals increases neurogenesis, research shows.

26 Feb 2013

Harmful effects of stress may be key to managing chronic pain

For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition.

25 Feb 2013

New research offers clues for chemotherapy-induced cognitive impairment

It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint - often referred to as chemo-brain - is common. The scientific cause, however, has been difficult to pinpoint.

22 Feb 2013

Tiny microscope can help scientists observe neuronal firings in the brain

If you want to read a mouse's mind, it takes some fluorescent protein and a tiny microscope implanted in the rodent's head.

20 Feb 2013

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, and its accumulation using a mouse model of Alzheimer's disease.

16 Feb 2013

Prions may be crucial in brain development during childhood

A molecule that is not only dangerous, but can help the brain grow. A few years ago it was found that certain proteins, the prions, when defective are dangerous, as they are involved in neurodegenerative syndromes such as the Creutzfeldt-Jakob and the Alzheimer diseases.

16 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

A group of Portuguese researchers from IBMC and FMUP at the University of Porto has found the reason why patients with chronic pain often suffer from impaired short -term memory.

9 Feb 2013

Location of altered brain metabolite levels found in bipolar I patients

Bipolar I disorder patients have increased phospholipid levels in the thalami and increased N-acetyl-aspartate levels in the left hippocampus compared with healthy individuals, a team of investigators has discovered.

5 Feb 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

Excessive alcohol use accounts for 4% of the global burden of disease, and binge drinking particularly is becoming an increasing health issue. A new review article published Cortex highlights the significant changes in brain function and structure that can be caused by alcohol misuse in young people.

2 Feb 2013

Review article highlights growing evidence for lasting impact of alcohol on the brain

31 Jan 2013

Scientists discover clear link between poor sleep, memory loss and brain deterioration of old age

The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory.

28 Jan 2013

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

Using a brain-imaging technique that examines the entire infant brain, researchers have found that the anatomy of certain brain areas - the hippocampus and cerebellum - can predict children's language abilities at 1 year of age.

22 Jan 2013

Family members with rare gene mutation at high risk of developing schizophrenia

Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.

22 Jan 2013

New model of tau pathology spread

Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised of pathological tau filaments.

19 Jan 2013

Dentate gyrus, fimbria volumes reduced in bipolar II disorder

Results from a Norwegian study suggest that the dentate gyrus and fimbria may play an important role in the pathophysiology of bipolar II disorder.

17 Jan 2013

Pannexin1 channel protein critical for memory and orientation

The channel protein Pannexin1 keeps nerve cells flexible and thus the brain receptive for new knowledge. Together with colleagues from Canada and the U.S., researchers at the Ruhr-Universit-t Bochum led by the junior professor Dr. Nora Prochnow from the Department of Molecular Brain Research describe these results in PLoS ONE.

10 Jan 2013

Hippocampus News and Research

Further Reading

Selective activation of the dentate gyrus can reduce anxiety without affecting learning

Schizophrenic people with MIR137 tend to develop illness at younger age

Study opens possibility for creating animal models of memory disorders

Loss of Dickopf-1 restores neurogenesis and memory in animal model

Harmful effects of stress may be key to managing chronic pain

New research offers clues for chemotherapy-induced cognitive impairment

Tiny microscope can help scientists observe neuronal firings in the brain

TSG might be novel compound for treatment of Alzheimer's and dementia with Lewy body

Prions may be crucial in brain development during childhood

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Study finds reason why patients with chronic pain often suffer from impaired short -term memory

Location of altered brain metabolite levels found in bipolar I patients

Review article highlights growing evidence for lasting impact of alcohol on the brain

Review article highlights growing evidence for lasting impact of alcohol on the brain

Scientists discover clear link between poor sleep, memory loss and brain deterioration of old age

Anatomy of certain brain areas can predict children's language abilities at 1 year of age

Family members with rare gene mutation at high risk of developing schizophrenia

New model of tau pathology spread

Dentate gyrus, fimbria volumes reduced in bipolar II disorder

Pannexin1 channel protein critical for memory and orientation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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