Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

New findings on Alzheimer's disease suggest a possible way for treatment

The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study.

7 Oct 2009

New treatment for Alzheimer's disease may be in the offing

Oleocanthal, a naturally-occurring compound found in extra-virgin olive oil, alters the structure of neurotoxic proteins believed to contribute to the debilitating effects of Alzheimer's disease. This structural change impedes the proteins' ability to damage brain nerve cells.

30 Sep 2009

DISC1 linked to proper development and migration of neurons in the brain

Scientists now have a better understanding of a perplexing gene that is associated with susceptibility for a wide spectrum of severely debilitating mental illnesses. Two independent research studies published by Cell Press in the September 24th issue of the journal Neuron provide fascinating insight into the molecular mechanisms that link disrupted-in-schizophrenia 1 (DISC1) with the proper development and migration of neurons in the hippocampus, a brain area involved in learning and memory and associated with the pathology of schizophrenia.

24 Sep 2009

Neurodegenerative disorders are the second-leading cause of early-onset dementia, says report

Neurodegenerative disorders called frontotemporal dementias (FTD) are the second-leading cause of early-onset dementia in persons under age 65 and can emerge sometimes as early as age 20.

21 Sep 2009

Molecular link between intelligence and curiosity discovered

Scientists from the Samuel Lunenfeld Research Institute of Mount Sinai Hospital in Toronto have discovered a molecular link between intelligence and curiosity, which may lead to the development of drugs to improve learning.

17 Sep 2009

UJI's current research study on early detection of Alzheimer's Disease using fMRI

The Universitat Jaume I (UJI) of Castelló is working on the early detection of Alzheimer's Disease by using functional magnetic resonance imaging (fMRI) techniques. The study is being carried out within the framework of a national project called MIND, which approaches Alzheimer's disease from a multidisciplinary perspective and involves twelve biomedicine companies and the corresponding public research organisations associated with them.

16 Sep 2009

Mechanism during sleep responsible for memory formation identified

A Rutgers University, Newark and Coll-ge de France, Paris research team has pinpointed for the first time the mechanism that takes place during sleep that causes learning and memory formation to occur.

16 Sep 2009

ADDF's grant to Abiant for developing accurate imaging diagnostic approach

The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it is providing a grant of $200,000 to Abiant, Inc. (Deerfield, IL), for the development of a highly accurate imaging diagnostic for Alzheimer's Disease.

9 Sep 2009

Prevalence of cortical gray matter atrophy may be overestimated in healthy aging brain

The belief that healthy older brains are substantially smaller than younger brains may stem from studies that did not screen out people whose undetected, slowly developing brain disease was killing off cells in key areas, according to new research. As a result, previous findings may have overestimated atrophy and underestimated normal size for the older brain.

8 Sep 2009

Early schizophrenia symptoms include unusually high CA1 subfield activity

In the first functional magnetic resonance imaging (fMRI) study of its kind, neurologists and psychiatrists at Columbia University have identified an area of the brain involved in the earliest stages of schizophrenia and related psychotic disorders.

7 Sep 2009

Studies reveal that obese people are at greater risk for developing Alzheimer's disease

Obesity is on a rampage, with the World Health Organization pegging the numbers at more than 300 million worldwide, with a billion more overweight. With obesity comes the increased risk for cardiovascular disease, Type II diabetes, and hypertension.

25 Aug 2009

MRI used as early warning system for Alzheimer's disease and dementia

When we absorb new information, the human brain reshapes itself to store this newfound knowledge. But where exactly is the new knowledge kept, and how does that capacity to adapt reflect our risk for Alzheimer's disease and other forms of senile dementia later in our lives?

12 Aug 2009

Alcoholics display abnormal brain activity when processing facial expressions

Researchers from Boston University School of Medicine (BUSM) have found that individuals who have a long history of alcoholism, but who have been abstinent for at least a month up to many years, showed abnormal brain activity when looking at facial expressions of others.

12 Aug 2009

Biological mechanisms contribute to stress resilience

It is important to understand what biological mechanisms contribute to an individual’s capacity to be resilient under conditions of extreme stress, such as those regularly experienced by soldiers, police, and firefighters.

5 Aug 2009

New clues about the roots of neurological disease

Switching off a key DNA repair system in the developing nervous system is linked to smaller brain size as well as problems in brain structures vital to movement, memory and emotion, according to new research led by St. Jude Children's Research Hospital scientists.

27 Jul 2009

Migrant neuron: New imaging studies reveal mechanics of neuron migration

The development of the brain proceeds a little like the European settlement of North America. The earliest pioneers settled on the east coast with subsequent waves of settlers forming communities further and further westward. In cortical regions of the developing brain, generations of young neurons undergo a staged migration as well, with the earliest-born cells staying relatively close to their birthplace and subsequent generations traveling further, ultimately stratifying into six neuronal layers in the mature brain. Now, for the first time, imaging studies have identified the "motors" that propel a unique form of cell migration that creates these layers that

22 Jul 2009

Scientists create new way to study brain function

Scientists at Duke University and the University of North Carolina have devised a chemical technique that promises to allow neuroscientists to discover the function of any population of neurons in an animal brain, and provide clues to treating and preventing brain disease.

15 Jul 2009

Brain imaging (MRI/PET) bring us closer to earlier detection of Alzheimer's

Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

14 Jul 2009

Topographical brain maps are new frontier to catch early schizophrenia

John Csernansky wants to take your measurements. Not the circumference of your chest, waist and hips. No, this doctor wants to stretch a tape measure around your hippocampus, thalamus and prefrontal cortex.

9 Jul 2009

Newborn brain cells improve our ability to navigate our environment

Although the fact that we generate new brain cells throughout life is no longer disputed, their purpose has been the topic of much debate. Now, an international collaboration of researchers made a big leap forward in understanding what all these newborn neurons might actually do. Their study, published in the July 10, 2009, issue of the journal Science, illustrates how these young cells improve our ability to navigate our environment.

9 Jul 2009