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High-resolution imaging with elastography could accurately spot breast cancer in surgical margins

A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer within the resected margins of surgical specimens taken from patients undergoing breast-conserving surgery.

15 Apr 2020

New AI system can evaluate endoscopic findings of ulcerative colitis with accuracy

Assessments of patients with ulcerative colitis, which is a type of inflammatory bowel disease, are usually conducted via endoscopy and histology. But now, researchers from Japan have developed a system that may be more accurate than existing methods and may reduce the need for these patients to undergo invasive medical procedures.

6 Mar 2020

New collapsible basket technology has big advantages for drug discovery, personalized medicine

A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples.

4 Mar 2020

New label-free microscopic techniques provide better visualization of extracellular vesicles

The Biophotonics Imaging Lab at the Beckman Institute for Advanced Science and Technology has developed imaging techniques that investigate tissues without using any staining or labels.

21 Feb 2020

Increased risk of uterine cancer linked to 24 gene variants

The risk of uterine endometrial cancer is increased by 24 gene variants that code for different cellular processes such as cell growth and death, gene regulation, and estrogen metabolism, according to a comprehensive review published in the Journal of Medical Genetics.

17 Feb 2020

'Watch-and-Wait' strategy may help rectal cancer patients to safely evade surgery

A team of doctors and scientists from the Champalimaud Clinical Centre in Lisbon, Portugal, and the Netherlands Cancer Institute in Amsterdam, has shown that patients with "low" rectal cancer (that is, very close to the anus) who show no sign of their tumors after a course of radio- and chemotherapy can safely choose to postpone invasive and complication-prone surgical procedures.

6 Feb 2020

Editor's Pick: Life Science Interviews from 2019

In this article, our editors look back at their favorite life science interviews from 2019.

17 Jan 2020

How SpatialOMx is Delivering New Insights into Disease Research

An interview with Shannon Cornett Ph.D, discussing the use of MALDI-guided spatial molecular analysis for biomarker discovery.

From Bruker Life Sciences Mass Spectrometry 14 Jan 2020

Novel artificial intelligence algorithm helps detect brain tumor

Researchers have developed a new imaging technique and artificial intelligence algorithm that can help identify brain tumors.

7 Jan 2020

Novel imaging technique produces accurate, real-time intraoperative diagnosis of brain tumors

A novel method of combining advanced optical imaging with an artificial intelligence algorithm produces accurate, real-time intraoperative diagnosis of brain tumors, a new study finds.

6 Jan 2020

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Final results are published from an evaluation of 42 patients treated with the immune checkpoint inhibitor nivolumab in the large multi-arm precision medicine trial, NCI-Molecular Analysis for Therapy Choice (NCI-MATCH or EAY131).

20 Dec 2019

Imaging technique and machine learning may provide accurate diagnosis of colorectal cancer

Colorectal cancer is the second most common type of cancer worldwide, with about 90% of cases occurring in people 50 or older.

5 Dec 2019

Stem cells do help restore heart function – but in a different way

A new study published in the journal Nature shows that stem cells do work well to repair the damaged heart – but in an entirely different manner than was originally supposed. The study shows that stem cells, whether living or dead, when injected into the area of damage in the heart in mice, activate an intense acute inflammation. This triggers the classic wound healing response which finally results in the partial or complete recovery of mechanical function of the injured area.

28 Nov 2019

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

The University of Barcelona and Hospital Clínic de Barcelona collaborate with Boehringer Ingelheim Inc. to improve the efficiency of nintedanib, an antiangiogenic and antifibrotic drug, for the treatment of lung cancer.

19 Nov 2019

TSU researchers develop new approach to diagnose adenocarcinoma

Scientists have developed a new approach to the diagnosis of adenocarcinoma - a malignant tumor of the prostate gland. Artificial intelligence is used to determine oncopathology and determine the stage of the disease with this approach.

13 Nov 2019

Does Parkinson's disease start in the brain or gut?

Does Parkinson's disease start in the brain or the gut? In a new contribution published in the Journal of Parkinson's Disease, scientists hypothesize that PD can be divided into two subtypes: gut-first, originating in the peripheral nervous system of the gut and spreading to the brain; and brain-first, originating in the brain, or entering the brain via the olfactory system, and spreading to the brainstem and peripheral nervous system.

7 Nov 2019

Histology News and Research

High-resolution imaging with elastography could accurately spot breast cancer in surgical margins

New AI system can evaluate endoscopic findings of ulcerative colitis with accuracy

New collapsible basket technology has big advantages for drug discovery, personalized medicine

New label-free microscopic techniques provide better visualization of extracellular vesicles

Increased risk of uterine cancer linked to 24 gene variants

'Watch-and-Wait' strategy may help rectal cancer patients to safely evade surgery

Editor's Pick: Life Science Interviews from 2019

How SpatialOMx is Delivering New Insights into Disease Research

Novel artificial intelligence algorithm helps detect brain tumor

Novel imaging technique produces accurate, real-time intraoperative diagnosis of brain tumors

Data results of NCI-MATCH trial in tumors with DNA mismatch repair deficiencies

Imaging technique and machine learning may provide accurate diagnosis of colorectal cancer

Stem cells do help restore heart function – but in a different way

Improving the efficiency of antiangiogenic and antifibrotic drug for treatment of lung cancer

TSU researchers develop new approach to diagnose adenocarcinoma

Does Parkinson's disease start in the brain or gut?

Study identifies a kinase as potential target to treat heart failure

NSU study points to another potential connection between sleep and overall good health

Shape of lung tissue fibers influences respiratory elasticity

Development and assessment of NGS-based microsatellite instability assay

Life Science Microscopy eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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