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New target for muscular dystrophy drug therapy

Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment.

13 Jul 2007

Uncooked fish linked with liver cancer in Asia

An age old preference for eating uncooked fish dishes like koi-pla puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week's PLoS Medicine.

10 Jul 2007

OncoLife web-based cancer survivorhip care plan

A team of cancer specialists from OncoLink.org, the award-winning cancer Web-based resource of the Abramson Cancer Center of the University of Pennsylvania, has launched OncoLife, the first and only individualized plan-of-care based on the national Institute of Medicine's recommendations for adult cancer survivors.

4 Jul 2007

New drug resistance screening method

A growing number of drug-resistant strains of HIV are a threat to the effectiveness of current treatments despite anti-HIV drug cocktails decreasing the number of HIV-related deaths and improving the quality of life for HIV patients.

29 Jun 2007

One in 10 hospice patients are referred too late for services

The study is based on surveys completed by bereaved family members and designed to gauge the quality of hospice programs, which provide medical care with social, emotional and spiritual support for the dying.

29 Jun 2007

More common for children with complex chronic conditions to die in their home than in a hospital

It is becoming more common for children with complex chronic conditions to die in their home than in a hospital, although black and Hispanic children with these conditions are less likely to die in their home, according to a study in the June 27 issue of JAMA: The Journal of the American Medical Association, a theme issue on chronic diseases of children.

27 Jun 2007

Mild cognitive disorder often an early symptom of Alzheimer's disease

Using new MRI techniques to analyze tissue composition and structure in the brain, researchers from the University of Pennsylvania School of Medicine and the National Institute on Aging successfully detected mild cognitive disorder (MCI), a condition in which patients suffer mild memory problems and is often an early symptom of Alzheimer's disease (AD).

14 Jun 2007

COX inhibitors may weaken protective qualities of estrogen therapy

Researchers from the University of Pennsylvania School of Medicine found in a database study of women heart patients that COX inhibitors such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs) may undermine any purported protection against heart disease in participants taking estrogen therapy.

24 May 2007

Mammals have the power to regenerate

Researchers at the University of Pennsylvania School of Medicine have found that hair follicles in adult mice regenerate by re-awakening genes once active only in developing embryos.

18 May 2007

Terminally-ill patients often denied chance to die at home

Many terminally-ill patients cannot die at home because of a lack of services and training in palliative care, say researchers from the University of Warwick.

8 May 2007

New and improved techniques to treat cardiac arrest

Professor of Emergency Medicine at the University of Pennsylvania School of Medicine, has been named Director of Penn's new Center for Resuscitation Science.

4 Apr 2007

NYT examines 'gray market' for in-home long-term care aides

Many middle-class families facing the "crushing burden of indefinite home-care expenses" have begun to hire in-home long-term care aides through the "gray market," an "over-the-back-fence network of women," although the practice "is fraught with risks," the New York Times reports.

4 Mar 2007

State proposals for universal health insurance unlikely to succeed

Democratic presidential candidate and former Sen. John Edwards (N.C.) recently released a universal health care proposal that incorporates "the bad idea of raising taxes on employers and forcing individuals to purchase insurance," but before "others get carried away with this model, they should take a look at its most recent manifestation in Massachusetts," Sally Pipes, president and CEO of the Pacific Research Institute, writes in a Wall Street Journal opinion piece.

27 Feb 2007

More insurers, programs offer 'open access' hospice care

Increasing numbers of hospice programs and private insurance companies are allowing patients to receive medical treatments while participating in hospice care, the New York Times reports.

13 Feb 2007

Health officials accused over cover up in deaths from vCJD

A cover up on the part of British health authorities meant a man who had been infected with CJD from contaminated blood during a transfusion was not told until he was dying what was really wrong with him.

11 Dec 2006

Terminally ill cancer patients continue to receive aggressive treatment at end of life

The increasing use of chemotherapy and intensive hospital treatment for cancer patients in their last two weeks of life continued at least into the late 1990s despite the growth of the hospice movement that emphasizes comforting personal bonds and controlling pain and discomfort

9 Jun 2006

Religious orientation influences elderly's fear of death

As they approach death, the churchgoing elderly are likely to find little solace in religion if they had little personal commitment to God during the rest of their lives, a new University of Florida study finds.

20 Apr 2006

HHS announces grants of $579.7 million to fund HIV/AIDS primary care

HHS Secretary Mike Leavitt has announced grants of $579.7 million to fund HIV/AIDS primary care and support services for low-income residents living in major metropolitan areas hit hardest by the HIV/AIDS epidemic.

17 Mar 2006

New guidelines to battle heart failure

Early diagnosis and new treatments can help battle heart failure -- a growing national problem that causes 1 million hospital admissions each year, according to new guidelines released by the American College of Cardiology (ACC) and the American Heart Association (AHA).

22 Aug 2005

Asian American and Pacific Island women less likely to receive breast-conserving surgery

Asian American and Pacific Island women, particularly those born abroad, are less likely to receive breast-conserving surgery for early-stage breast cancer than non-Hispanic white women, according to a study published in the online Journal of General Internal Medicine.

17 Jul 2005