Huntington’s Disease News and Research

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Myelin and Huntington's disease

Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease.

14 Jun 2007

Funding to upgrade stem cell research facilities at UC San Diego

The University of California, San Diego (UCSD) Human Stem Cell Core Facility, which supports multiple research projects using stem cells to advance the understanding and ultimately the treatment of disease and injury, will receive a $2.8 million Shared Research Laboratory Grant from the California Institute for Regenerative Medicine (CIRM).

8 Jun 2007

Circulating tumor cells predict how prostate cancer patients do with chemotherapy

The number of tumor cells circulating in the bloodstream of patients with metastatic, hormone-resistant, prostate cancer can predict how they will do with chemotherapy, according to results of an international trial.

5 Jun 2007

AMPAKINE drugs may provide protection from drug-induced respiratory depression

Drug-induced respiratory depression is a life-threatening condition caused by analgesic, hypnotic, and anesthesia medications.

5 Jun 2007

Common antipsychotic drug for methamphetamine overdose may damage brain cells

A common antipsychotic drug used in emergency rooms to treat methamphetamine overdose damages nerve cells in an area of the brain known to regulate movement, a new study shows.

30 May 2007

Researchers develop first images of physical changes in brain cells thought to underlie memory

University of California, Irvine researchers have developed the first images of the physical changes in brain cells thought to underlie memory, a discovery that is already uncovering clues about memory loss linked to cognitive disorders.

17 May 2007

Scientists convert the sequence of proteins into music

UCLA molecular biologists have turned protein sequences into original compositions of classical music.

17 May 2007

Researchers catch moving proteins in mid-fold

Any photographer can vouch for the difficulty of capturing a clear picture of a moving target.

17 May 2007

Subtle signs can help doctors predict that a person will develop Huntington's disease

Huntington's disease is a genetic disorder that affects movement, thinking, and some aspects of personality. There is no treatment or cure for the disease.

17 May 2007

Radically different approach to nuclear magnetic resonance

Detecting the molecular structure of a tiny protein using nuclear magnetic resonance (NMR) currently requires two things: a million-dollar machine the size of a massive SUV, and a large sample of the protein under study.

16 May 2007

Coenzyme Q10 does not improve Parkinson's disease symptoms

Small doses of the antioxidant coenzyme Q10 appear to increase blood levels of this naturally occurring compound in patients with Parkinson's disease, but does not improve Parkinson's disease symptoms, according to an article posted online today that will appear in the July 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

15 May 2007

Scientists find new proteins involved in Huntington's disease

Researchers in the United States have identified more than 200 new proteins that are involved in Huntington's disease.

14 May 2007

Identification of 200 new proteins that interact with the mutated protein that causes Huntington's disease

The identification of more than 200 new proteins that interact with the mutated protein that causes Huntington's disease opens the door to developing treatments for the fatal neurodegenerative disorder, said a Baylor College of Medicine researcher who took part in the work that appears online today in the journal Public Library of Science Genetics.

11 May 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Zorro-LNA stops genetic disorders in their tracks

A study to appear in the June 2007 issue of The FASEB Journal describes a new agent, called "Zorro-LNA," which has the potential to stop genetic disorders in their tracks.

1 May 2007

Avicena files composition of matter patent application for treatment of Huntington's disease

Avicena Group has announced day that it has filed a composition of matter patent application with the United States Patent and Trademark Office (USPTO) to cover potential treatments for Huntington's disease, a fatal neurodegenerative disease.

1 May 2007

Miscue of body's genetic repair system may cause Huntington's disease

Mayo Clinic researchers, along with collaborators from the National Institutes of Health (NIH) and University of Oslo, Norway, have discovered that a miscue of the body's genetic repair system may cause Huntington's disease, a fatal condition that affects 30,000 Americans annually by destroying their nervous system.

24 Apr 2007

New treatment possibilities for Huntington's disease

Howard Florey Institute have opened up new treatment possibilities for Huntington's disease by proving a scientific theory incorrect.

3 Apr 2007

Molecular mechanism involved in development of schizophrenia

In studying the postmortem brain tissue of adults who had been diagnosed with schizophrenia, the researchers found that levels of certain gene-regulating molecules called microRNAs were lower among schizophrenia patients than in persons who were free of psychiatric illness.

30 Mar 2007