Hydroxychloroquine News and Research

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Most DMARDs not linked with the risk of Parkinson's disease in people with rheumatoid arthritis

The autoimmune disorder rheumatoid arthritis has been associated with a lower risk of Parkinson's disease (PD) in previous studies, with antirheumatic drugs as one possible explanatio

24 Jan 2022

Antimicrobial resistance causes more deaths than HIV and malaria

Antibiotic-resistant bacterial infections resulted in more than 1.2 million deaths worldwide in 2019, exceeding the number caused by HIV/AIDS and malaria, says a study spanning 204 countries and territories.

22 Jan 2022

Meta-analysis confirms complete failure of hydroxychloroquine/chloroquine as a COVID-19 treatment

Researchers investigate the efficacy of hydroxychloroquine and chloroquine in the treatment of patients hospitalized with COVID-19.

17 Jan 2022

Researchers find a digital silver lining in failed COVID-19 drug trial

A clinical trial in which two test drugs failed to help patients with mild COVID-19 nevertheless had a silver lining: It proved the viability of a study model in which a medication's potential arrhythmic side effects are safely, effectively monitored without the participants ever setting foot in a hospital or clinic.

20 Dec 2021

Frequent cognitive impairments after 4-month follow-up in ICU COVID-19 patients

Results from a recent observational study published in the Journal Of The Neurological Sciences found that after a 4-month follow-up, ICU patients with severe COVID-19 illness were more likely to have mild cognitive impairment with features related to a diffuse encephalopathy than patients with mild infection who do not need a ventilator. Additionally, ICU patients experienced more significant impairment in executive function. All neurological deficits involve the peripheral nervous system.

14 Dec 2021

Screening FDA-approved compounds shown to possess antiviral or antimicrobial activity for SARS-CoV-2 inhibition

Researchers have screened several compounds that could show the ability to inhibit SARS-CoV-2.

10 Dec 2021

Convalescent plasma not recommended for patients with covid-19, WHO experts say

Convalescent plasma (a transfusion of blood plasma from someone who has recovered from covid-19) is not recommended for patients with covid-19, says a WHO Guideline Development Group of international experts in The BMJ today.

7 Dec 2021

Hospitals refused to give patients ivermectin. Lockdowns and political pressure followed.

One Montana hospital went into lockdown and called police after a woman threatened violence because her relative was denied her request to be treated with ivermectin.

2 Dec 2021

Natural triterpenoids in licorice found to inhibit SARS-CoV-2

In new studies, researchers concluded that licorice triterpenoids could be candidates for anti-SARS-CoV-2 drug developments.

2 Dec 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Could drugs derived from microalgae be effective against COVID-19?

Researchers discuss the ability of some microalgae metabolites to prevent cytokine storm syndrome during COVID-19.

15 Nov 2021

Current understanding of the link between COVID-19 and cardiovascular disease

A review published in Chemo-Biological Interactions has focused on the prevalence of COVID-19 in CVD patients associated with ACE2 mechanisms.

10 Nov 2021

Conspiracists during the COVID-19 pandemic

A researcher from the University of Pennsylvania has commented on how conspiracy theories misrepresent scientific data and advice.

8 Nov 2021

As constituents clamor for ivermectin, Republican politicians embrace the cause

When state senators in South Carolina held two hearings in September about covid-19 treatments, they got an earful on the benefits of ivermectin — which many of the lawmakers echoed, sharing experiences of their own loved ones.

8 Nov 2021

Automated method shows predictive power for COVID-19 in-hospital mortality

Researchers focussed on the S-learner strategy of estimating the conditional average treatment effect.

4 Nov 2021

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that higher doses, longer duration of use, chronic kidney disease and Asian race could all be independent risk factors for retinopathy in people using hydroxychloroquine, an antimalarial drug commonly used to treat lupus, rheumatoid arthritis and other diseases.

1 Nov 2021

Chlorophyll catabolite pheophorbide A shows potential against SARS-CoV-2

A new study identifies a potent SARS-CoV-2 antiviral, Pheophorbide a (PheoA), which is a compound derived from the plant Marchantia polymorpha L.

27 Oct 2021

Can targeting autophagy become a new approach to COVID-19 treatment?

In a recent review, the author discusses autophagy as a contributing mechanism of selected drugs that are currently being evaluated to treat COVID‐19.

25 Oct 2021

Public and environmental health effects of the pandemic revealed by chemical analyses of wastewater

When investigators analyzed primary sludge collected during the first wave of COVID-19 (March 19 to June 30, 2020) at a wastewater treatment plant in Connecticut, they found trends in the presence of chemicals that related directly to the pandemic-;for example, hydroxychloroquine had elevated concentrations in the week following Emergency Use Authorization of the drug for the treatment of COVID-19.

20 Oct 2021