Hypersensitivity News and Research

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Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.

FDA approves Enablex for the treatment of overactive bladder

Novartis Pharmaceuticals Corporation today announced that the U.S. Food and Drug Administration (FDA) has approved Enablex® (darifenacin) extended-release tablets (7.5mg and 15mg) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency.

22 Dec 2004

Detrol LA significantly reduces symptoms of overactive bladder

Pfizer today announced results of a comprehensive six-year review of efficacy and safety data for Detrol LA (tolterodine tartrate extended release capsules) indicating that Detrol LA significantly reduces symptoms of overactive bladder (OAB) with a low occurrence of side effects, and should be considered first-line therapy.

13 Dec 2004

FDA approval of cream to treat bacterial vaginosis

KV Pharmaceutical Company has announced that it has received approval from the United States Food and Drug Administration (FDA) to market Clindesse (clindamycin phosphate) Vaginal Cream, 2%, a single-dose prescription cream therapy indicated to treat bacterial vaginosis ("BV").

3 Dec 2004

FDA approval of Tysabri, for the treatment of multiple sclerosis

Biogen and Elan Corporation have announced that the U.S. Food and Drug Administration (FDA) has approved Tysabri (natalizumab), as treatment for relapsing forms of multiple sclerosis (MS) to reduce the frequency of clinical relapses.

24 Nov 2004

Wyeth gets approval for needle-less syringe for the treatment of hemophilia

Wyeth Pharmaceuticals has announced that it has received approval from the U.S. Food and Drug Administration (FDA) for the ReFacto Antihemophilic Factor (Recombinant) R2 Kit, the first needle-less reconstitution device with a prefilled diluent syringe for hemophilia.

14 Sep 2004

Regular exercise boosts immune system in older men

As it turns out, judging by the reaction strength of their immune system to an unknown, but harmless, protein antigen, it’s possible for men over 70 to mount an immune response similar to that produced by much younger men -- if they get regular moderate physical activity of about six hours a week.

25 Aug 2004

Pfizer drug effectively treats overactive bladder symptoms

Women with mixed incontinence, a combination of overactive bladder and stress incontinence, reported a greater treatment benefit for overactive bladder symptoms from DETROL® LA (tolterodine tartrate extended release capsules) than placebo, according to new study results published in the August issue of Urology.

21 Aug 2004

Methods using preventive analgesia to treat pain after surgery before it develops

York University Professor Joel Katz is studying methods of preventing or significantly reducing pain after surgery by employing preemptive or preventive analgesia to treat pain before it develops.

17 Aug 2004

Misfiring proteins linked to sick feeling of type 2 diabetics

After a series of studies in the laboratory of Dr. Gregory Freund, a clearer picture is emerging: A disruption of signaling proteins in the immune system may be responsible for the inflammation that makes someone with type 2 diabetes feel sick and increases the risk of serious complications.

29 Jul 2004

Plan B has been shown to reduce the risk of pregnancy by 89 percent

Barr Pharmaceuticals has announced that its subsidiary, Duramed Pharmaceuticals has submitted a formal response in support of its Supplemental New Drug Application (sNDA) for an Over-the-Counter (OTC) Plan B(R) emergency contraceptive product.

23 Jul 2004

Women with a condition called vulvodynia process pain differently

The researchers tested 17 women with vulvodynia and 23 similar women without pain at 23 sites throughout the vulva and at the deltoid muscle, the shin and the thumbnail to assess pain tolerance. They found the women with vulvodynia had lower tolerance at all sites than the women without vulvodynia.

13 Jul 2004

Unique project to find out if mobile phone masts, have an adverse effect on our health

Researchers at the University of Essex, England are embarking on the first phase of a unique project to find out if mobile phone masts, have an adverse effect on our health.

29 Jun 2004

Investigational drug Abraxane is active and well tolerated in women with metastatic breast cancer

Investigational drug Abraxane™ (albumin nanoparticle paclitaxel), administered weekly without steroid premedication, is active and well tolerated in women with metastatic breast cancer whose disease had progressed while they were treated with paclitaxel (Taxol®) and/or docetaxel (Taxotere®).

15 Jun 2004

Microbes in your gut could be cause of allergies

Allergies making your life miserable? Tired of popping antihistamines like candy? Can't go anywhere without your inhaler? The real problem may not be your stuffed-up head. It could be the microbes in your gut.

1 Jun 2004

Antibiotics could be the cause of many allergies

27 May 2004

Scientific evidence links mold in homes and buildings to people with chronic asthma symptoms

Scientific evidence links mold and other factors related to damp conditions in homes and buildings to asthma symptoms in some people with the chronic disorder, as well as to coughing, wheezing, and upper respiratory tract symptoms in otherwise healthy people, says a new report from the Institute of Medicine of the National Academies.

25 May 2004

Clinical use of immunoassays not recommended as a primary means of assessing environmental fungal exposure

Routine clinical use of immunoassays, a type of blood test for measuring antigen-specific IgE or IgG antibodies, is not recommended as a primary means of assessing environmental fungal exposure or its harmful effects according to a report published this month in Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

24 May 2004

Physicians perceive overactive bladder as a normal part of aging when in fact it is a treatable medical condition

Nearly half of people with symptoms of overactive bladder had to initiate multiple conversations with their doctor before receiving a diagnosis or treatment, according to a national survey of more than 500 people with symptoms of overactive bladder. Furthermore, only 15 percent of those surveyed said their doctors had ever initiated a discussion about overactive bladder symptoms.

12 May 2004

Intranasal influenza vaccine may help induce broader immunity in children than the traditional flu shot

MedImmune, Inc. has announced clinical data showing that a live, attenuated intranasal influenza vaccine (LAIV) may help induce broader immunity in children against drifted influenza strains when compared to the traditional flu shot (TIV).

2 May 2004

$Untreated postmenopausal women with osteoporosis are at risk for first spinal fracture within one year$

Untreated postmenopausal women with osteoporosis are at risk for first spinal fracture within one year

Results of a new analysis found that, without treatment, one out of 13 postmenopausal osteoporotic women who were initially fracture-free were likely to experience a spinal fracture within one year.

28 Apr 2004