Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Popular painkiller Nurofen Plus in danger of becoming a prescription only drug

Australia's National Drugs and Poisons Scheduling Committee (NDPSC) is apparently considering making one of the most commonly used over-the-counter (OTC) drugs available only with a prescription.

15 Apr 2008

Ibuprofen and acetaminophen shown to increase muscle mass and muscle strength

Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University.

7 Apr 2008

Poison prevention starts with respecting, inspecting medicines

Between tots' cough and cold medicines being pulled from store shelves, and a New York teenager dying from a muscle-cream overdose, the past year's scares are grounds for renewing a healthy fear for the products stowed in your medicine cabinet.

19 Mar 2008

Aspirin/NSAID interaction in treatment for second stroke

Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin's ability to act as an anti-platelet agent, researchers at the University at Buffalo have shown.

13 Mar 2008

Aspirin reduces the risk of breast cancer

According to a new British report, taking drugs such as Aspirin can reduce the risk of breast cancer by as much as 20 percent.

10 Mar 2008

Guidelines for von Willebrand disease diagnosis and management

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health today issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

4 Mar 2008

New guidelines for von Willebrand disease

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, has issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

1 Mar 2008

Risks of CVD for COX-2 inhibitors lower than previously reported

In an article published in the March issue of the Journal of Cardiovascular Pharmacology and Therapeutics, researchers from Florida Atlantic University (FAU) assess the totality of evidence, including strengths and limitations of different types of evidence contributing to the debate about cardiovascular disease (CVD) risks of cyclooxygenase-2 (COX-2) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

27 Feb 2008

Less waste in the synthesis of anti-inflammatory drugs

Dr Francesca Paradisi of the Centre for Synthesis and Chemical Biology (CSCB) at University College Dublin, and Professor Daria Giacomini and co-workers at the University of Bologna, Italy, have developed a highly efficient enzyme-driven process which could be applied to the synthesis of drugs such as Ibuprofen, avoiding the 50% waste of the undesired byproduct generated by current processes.

4 Feb 2008

NSAIDs are effective for short-term relief of low-back pain

Non steroidal anti-inflammatory drugs (NSAIDs; such as aspirin and ibuprofen) can help reduce symptoms of low back pain that doesn't involve sciatica, a Cochrane Systematic Review has found.

24 Jan 2008

Blacks, Hispanics less likely to get strong pain drugs in emergency rooms

Despite increases in the overall use of opioid drugs to relieve severe pain, black and Hispanic patients remain significantly less likely than whites to receive these pain-relievers in emergency rooms, according to a new national study.

2 Jan 2008

Benefits of ibuprofen shown to outweigh risks of gastrointestinal bleeding in children with cystic fibrosis

Treatment with ibuprofen is associated with a significantly slower rate of decline in lung function in children and adolescents with cystic fibrosis, according to a new study.

3 Dec 2007

Watson Pharmaceuticals receives FDA approval for generic Combunox

Watson Pharmaceuticals, Inc. has announced that it has received final approval from the United States (U.S.) Food and Drug Administration (FDA) on its Abbreviated New Drug Application (ANDA) for Oxycodone Hydrochloride and Ibuprofen Tablets (CII) in the 5 mg/400 mg strength.

27 Nov 2007

Common painkillers may prevent Parkinson's disease

Researchers in the U.S. are suggesting that painkillers such as ibuprofen and naproxen can cut the risk of Parkinson's disease by as much as 60%.

6 Nov 2007

NSAIDs may lower risk of Parkinson's disease

Over-the-counter pain medications known as non-steroidal anti-inflammatory drugs (NSAIDs) may reduce a person's risk of Parkinson's disease, according to a study published in the November 6, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.

6 Nov 2007

Long-term high-dose ibuprofen slows the rate of decline in lung function in children with cystic fibrosis

The most important clinical problem for people with cystic fibrosis (CF) is inflammation of their lungs.

17 Oct 2007

Chili peppers and pain relief

Purified capsaicin, a drug derived from chili peppers, reduced pain for at least three days following groin hernia surgery, according to a new study.

15 Oct 2007

Taking antidepressants with painkillers dangerous

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

9 Oct 2007

Mutation of the COX2 gene can double or treble a woman's risk of ovarian cancer

Researchers in Portugal have discovered that a specific mutation of the COX2 gene seems to play a role in the onset of ovarian cancer, increasing women's susceptibility to developing the disease.

26 Sep 2007

Ibuprofen effective in slowing down lung disease in children with cystic fibrosis

The results of a clinical trial, published in late August in the Journal of Pediatrics, indicates that, when used as part of routine therapy, high-dose ibuprofen is safe, and effective in slowing down lung disease in children with cystic fibrosis (CF).

5 Sep 2007