Immune Response News and Research

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New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Are people with HIV at a higher risk of severe COVID-19 outcomes?

The research review indicates that people with HIV, especially those with low CD4 cell counts, face greater risks of severe COVID-19 outcomes and have suboptimal immune responses to SARS-CoV-2. Antiretroviral therapy aids in clearing infections, and a third vaccine dose reduces the risk of breakthrough infections among this population.

15 Oct 2023

Newly discovered synthetic adjuvant materials could make vaccines more accessible, sustainable

New raw vaccine materials that could make vaccines more accessible, sustainable, and ethical have been discovered.

14 Oct 2023

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

New research helps explain why young children have lower rates of severe COVID-19 than adults. A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.

13 Oct 2023

Scientists discover feedback loop that controls itch and inflammation

It can be a relief to scratch the occasional itch, but when itch gets out of control, it can become a serious health problem. How does the body know when to stop?

13 Oct 2023

New study finds host strategy to cope with sleeping sickness

A new study led by Luísa Figueiredo, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), and published today in the scientific journal Nature Microbiology found a new strategy by the host to cope with Trypanosoma brucei infection.

12 Oct 2023

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

The oral manifestations of CD.

12 Oct 2023

Maternal pertussis vaccination boosts infant protection up to eight months

In a large-scale Australian study, maternal vaccination during pregnancy significantly increased pertussis resistance in infants up to eight months. While it slightly reduced the effectiveness of infants' routine vaccinations, it did not increase infection risk.

11 Oct 2023

Study sheds light on how the immune system differentiates between self and non-self antigens

A groundbreaking study, led by Professor Kyemyung Park and his research team in the Graduate School of Health Science and Technology and the Department of Biomedical Engineering at UNIST has shed light on the intricate mechanism behind the immune system's ability to differentiate between self and non-self antigens.

11 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

New nanocapsule treatment boosts immune response against solid tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

11 Oct 2023

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

The intricate interactions between gut microbiota and drugs.

11 Oct 2023

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

Genes may be responsible for third of complex regional pain syndrome cases. But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

10 Oct 2023

New method produces highly pure mRNA vaccines with less inflammation risk

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

10 Oct 2023

COVID-19 vaccine response lower in patients with lung conditions, study finds

Clinicians and researchers at National Jewish Health studied COVID vaccine effectiveness in patients with underlying lung conditions such as asthma, chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD).

10 Oct 2023

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

9 Oct 2023

FDA approves the use of sound waves to break down tumors in humans for liver treatment

The U.S. Food and Drug Administration has approved the use of sound waves to break down tumors—a technique called histotripsy—in humans for liver treatment.

9 Oct 2023

Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Researchers from Cima and the Clínica Universidad de Navarra, together with the international cooperative group Diffuse Midline Glioma (DMG-ACT), have confirmed that blocking an immune checkpoint molecule reduces the tumor and prolongs survival in animal models of the most aggressive childhood cancer. This research, carried out at the Cancer Center Clínica Universidad de Navarra, shows that inhibition of TIM-3 promotes the immune memory of diffuse intrinsic stem glioma (DIPG) and improves the prognosis of the disease.

9 Oct 2023

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Researchers use cryo-EM and molecular dynamics to reveal conformational changes in the spike proteins of human coronavirus HKU1 upon binding with a receptor. Findings unveil the complexity of beta coronavirus attachment, suggesting a more intricate mechanism of host cell invasion than previously understood.

8 Oct 2023

Immune Response News and Research

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

Are people with HIV at a higher risk of severe COVID-19 outcomes?

Newly discovered synthetic adjuvant materials could make vaccines more accessible, sustainable

Strong antibody response and nasal cytokines may protect young children from severe COVID-19

Scientists discover feedback loop that controls itch and inflammation

New study finds host strategy to cope with sleeping sickness

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

Maternal pertussis vaccination boosts infant protection up to eight months

Study sheds light on how the immune system differentiates between self and non-self antigens

Pitt scientists develop new approach to reduce side effects of organ transplants

New nanocapsule treatment boosts immune response against solid tumors

Exploring the link between drugs and microbiota: a growing imperative in precision medicine

Study supports genetic predisposition to chronic regional pain syndrome in a third of cases

New method produces highly pure mRNA vaccines with less inflammation risk

COVID-19 vaccine response lower in patients with lung conditions, study finds

Bio-inspired drug restores the effectiveness of immune cells in fighting cancer

FDA approves the use of sound waves to break down tumors in humans for liver treatment

Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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