Immune System News and Research

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IRX Therapeutics and Japan's NCRC collaborate to evaluate peptide-based cancer vaccines

IRX Therapeutics, a developer of novel immunomodulators to treat cancer and viral diseases, today announced that it has established a strategic collaboration with Japan's National Cancer Research Center (NCRC) to evaluate next-generation peptide-based cancer vaccines. Clinical research will be conducted at NCRC. IRX Therapeutics will provide its proprietary IRX-2 immunomodulatory regimen, clinical trial design and technical support. This is the first collaboration of its kind between the NCRC and a U.S.-based biotechnology firm.

30 Apr 2010

TenX Biopharma signs Clinical Trial Agreement with NCI

TenX Biopharma, Inc., announced today it has signed a Clinical Trial Agreement with the National Cancer Institute to conduct an investigator sponsored Phase II clinical trial.

30 Apr 2010

PROVENGE receives FDA approval for treatment of CRPC

Dendreon Corporation today announced that the U.S. Food and Drug Administration has approved PROVENGE (sipuleucel-T), an autologous cellular immunotherapy for the treatment of asymptomatic or minimally symptomatic metastatic, castrate-resistant (hormone-refractory) prostate cancer.

30 Apr 2010

Summer born babies more at risk of multiple sclerosis, says research

A recent study in Australia has found a link between low exposure to sunlight during the first three months of pregnancy and development of multiple sclerosis (MS) later in life of the baby.

30 Apr 2010

Dietary changes may help alleviate celiac disease, says study

New research published in the Journal of Leukocyte Biology suggests that striking a balance of intestinal microbiota could play a role in early stages of celiac disease-related immune responses

30 Apr 2010

FDA approves new treatment option for prostate cancer

Today is an exciting day for men with advanced prostate cancer and the millions of families and loved ones who are profoundly affected. Today a new prostate cancer treatment option, Provenge, was approved by the Food and Drug Administration.

30 Apr 2010

Tel Aviv scientist uncovers a new way of detecting multiple sclerosis

Multiple sclerosis (MS) is an equal opportunity destroyer. It attacks the central nervous system and eventually renders most patients disabled. Among its high-profile victims are celebrated cellist Jacqueline du Pre, whose career was ended by MS, and Joan Didion, one of America's greatest writers - but they are far from alone.

30 Apr 2010

Provenge cellular immunotherapy for men with advanced prostate cancer receives FDA approval

The U.S. Food and Drug Administration today approved Provenge (sipuleucel-T), a new therapy for certain men with advanced prostate cancer that uses their own immune system to fight the disease.

30 Apr 2010

Researchers identify key protein that regulates innate immune system

A team of researchers led by Baylor College of Medicine has identified a protein called NLRC5, a member of the NOD-like protein family, that is involved in inhibition of protein complexes key to critical pathways of innate immunity called NF-κB and type I interferon signaling. A report on their work appears in the current issue of the journal Cell.

30 Apr 2010

Canadian researchers identify new therapeutic target for lung cancer

Lung cancer patients whose tumors over-express a cell surface molecule called CXCR4 do significantly worse than those who do not, Canadian researchers have found. Their work, reported at the 2nd European Lung Cancer Conference in Geneva, highlights the exciting possibility that the molecule could soon become a new target for personalized cancer therapy.

30 Apr 2010

FDA approves Provenge prostate cancer vaccine

Cancer may now be fought with a vaccine. The FDA has finally approved an immune boosting vaccine which is said to extend survival of patients at an advanced stage of prostate cancer by four months. This is twice as long as what could be expected with regular chemotherapy. There is also an increase of three years survival after detection in initial stage by 38% thanks to the vaccine.

30 Apr 2010

Research initiative to study impact of microbes on human health, disease

The human species is dependent for its survival on the billions of microorganisms that inhabit multiple environmental niches within and on the human body. While microbes are commonly associated with diseases and infections, they are also vital in essential, beneficial roles such as digestion, where they help synthesize vitamins and ferment complex indigestible carbohydrates.

29 Apr 2010

Nanotechnology for study of individual molecule interaction in live cells

A University of Alberta-led research team has taken a major step forward in understanding how T cells are activated in the course of an immune response by combining nanotechnology and cell biology. T cells are the all important trigger that starts the human body's response to infection.

29 Apr 2010

OMT beneficial as adjunctive treatment in elderly people with pneumonia

A clinical trial of 406 subjects 50 years of age and older who were hospitalized with pneumonia showed a one-day reduction in the length of hospital stay in those patients who received osteopathic manipulative treatment (OMT) in addition to conventional medical care when compared to patients who received only conventional medical care. A per protocol analysis also showed a significant reduction in the duration of intravenous antibiotics and in respiratory failure or death in the group that received OMT when compare to the conventional care only group.

29 Apr 2010

Preventing HPV infection could slow HIV epidemic, say researchers

Men infected with human papillomavirus are at greater risk of becoming infected with human immunodeficiency virus than men who are not HPV positive, according to researchers at the University of North Carolina at Chapel Hill.

29 Apr 2010

Majority of women feel expectations on careers, appearances and healthy lifestyles are more magnified than ever

Today's women juggle many roles from the elusive work-life balance, to aspiring careers to even the 'yummy mummy' phenomenon. In fact, according to a new international women's poll conducted by Environics Research - commissioned by Multibionta(TM) - women across the globe agree career pressures, expectations for maintaining appearances and a healthy lifestyle are more magnified today versus 20 years ago.

29 Apr 2010

CD8+T cells may aid in developing AIDS vaccine: New Journal of Physics

Limited success in modelling the behaviour of the complex, unusual and unpredictable HIV virus has slowed efforts to develop an effective vaccine to prevent AIDS.

29 Apr 2010

Higher the blood cholesterol level, greater the risk of atherosclerosis: Study

In addition to crystallized cholesterol, atherosclerotic plaques always contain large quantities of immune cells but, surprisingly, no bacteria or viruses. It was previously unclear just how the body's own defence forces are called into action. Even animals that are kept in an absolutely sterile environment can suffer from "clogging" or "furring" of the arteries when their food contains high levels of cholesterol.

29 Apr 2010

Study examines lifestyle-related causes of death in AIDS patients

The study, by researchers from the University of Bristol and a large group of international collaborators, examined data from the Antiretroviral Therapy Cohort Collaboration (ART-CC) which involved nearly 40,000 patients who started ART between 1996 and 2006 in Europe and North America.

29 Apr 2010